calcium channel, voltage-dependent, L type, alpha 1C subunit

Synonym

Cacna1c, Cacn2, L-type Cav1.2, MBC, (alpha)1 subunit, Voltage-gated calcium channel subunit alpha Cav1.2, Mouse brain class C, Cach2, Cchl1a1, Cav1.2, MELC-CC, Cacnl1a1

normal 40 tissues
developmental tissues and primary cells（FANTOM5 CAGE）

Choropleth map on BodyParts3D

Choropleth maps on 3D human body images were generated by the relative gene expression values measured by GeneChip.

Classification in 40 Organs

brain

blood

connective

EST

cerebrum:12.20

cerebellum:-

brain stem:-

corpus callosum/glia:-

pineal gland:-

peripheral nerve:38.20

spine:-

retina:32.10

eye:-

artery/aorta:-

vein:-

lymphnode:-

peripheral blood:-

spleen:-

thymus:-

bone marrow:-

adipose:-

bone:-

skin:-

GeneChip

cerebrum:7.49

cerebellum:6.79

brain stem:-

corpus callosum/glia:-

pineal gland:-

peripheral nerve:7.29

spine:6.25

retina:6.19

eye:5.37

artery/aorta:-

vein:6.32

lymphnode:5.26

peripheral blood:-

spleen:5.31

thymus:-

bone marrow:4.98

adipose:5.35

bone:5.22

skin:5.27

CAGE

cerebrum:4.13

cerebellum:-

brain stem:3.43

corpus callosum/glia:-

pineal gland:-

peripheral nerve:-

spine:2.89

retina:-

eye:-

artery/aorta:2.50

vein:-

lymphnode:1.69

peripheral blood:-

spleen:0.93

thymus:0.49

bone marrow:-

adipose:-

bone:1.02

skin:1.96

RNA-seq

cerebrum:3.77

cerebellum:-

brain stem:-

corpus callosum/glia:-

pineal gland:-

peripheral nerve:-

spine:-

retina:-

eye:-

artery/aorta:-

vein:-

lymphnode:-

peripheral blood:-

spleen:-

thymus:-

bone marrow:-

adipose:-

bone:-

skin:-

reproductive

muscular

alimentary

liver

lung

urinary

endo/exo-crine

EST

uterus:-

placenta:27.60

prostate:-

ovary:-

testis:7.40

heart:74.40

muscle:-

esophagus:-

stomach:-

intestine:-

colon:-

liver/hepato:-

lung:-

bladder:66.20

kidney:-

pituitary:-

thyroid/parathyroid:-

adrenal gland:-

pancreas:9.40

breast:-

salivary:-

GeneChip

uterus:7.74

placenta:5.29

prostate:5.38

ovary:6.85

testis:5.05

heart:10.80

muscle:5.19

esophagus:-

stomach:6.01

intestine:6.03

colon:-

liver/hepato:4.94

lung:7.16

bladder:8.03

kidney:5.09

pituitary:6.17

thyroid/parathyroid:-

adrenal gland:8.91

pancreas:4.93

breast:5.48

salivary:5.43

CAGE

uterus:3.83

placenta:1.29

prostate:2.11

ovary:3.39

testis:0

heart:-

muscle:-

esophagus:-

stomach:1.07

intestine:1.55

colon:1.93

liver/hepato:0.26

lung:3.23

bladder:4.01

kidney:-

pituitary:2.98

thyroid/parathyroid:-

adrenal gland:4.56

pancreas:1.30

breast:2.05

salivary:-

RNA-seq

uterus:-

placenta:-

prostate:-

ovary:-

testis:-

heart:-

muscle:16.47

esophagus:-

stomach:-

intestine:-

colon:-

liver/hepato:0

lung:-

bladder:-

kidney:-

pituitary:-

thyroid/parathyroid:-

adrenal gland:-

pancreas:-

breast:-

salivary:-

IDs

Refseq ID	NM_001159535
Gene ID	12288
Unigene ID	Mm.436656
Probe set ID	1421297_a_at [Mouse430_2]
Ensembl ID	ENSMUSG00000051331

Orthologous Gene

Human[31]	NM_000719, NM_001129827, NM_001129829, NM_001129830, NM_001129831, NM_001129832, NM_001129833, NM_001129834, NM_001129835, NM_001129836, NM_001129837, NM_001129838, NM_001129839, NM_001129840, NM_001129841, NM_001129842, NM_001129843, NM_001129844, NM_001129846, NM_001167623, NM_001167624, NM_001167625
Rat [0]

Chromosomal Region

6F1 [118,542,314 - 119,146,249]

Search genes near this gene
- Between -5kb and +5kb
- Between -10kb and +10kb

Gene Family (Interpro ID)

IPR002077	Voltage-dependent calcium channel, alpha-1 subunit
IPR005446	Voltage-dependent calcium channel, L-type, alpha-1 subunit
IPR005451	Voltage-dependent calcium channel, L-type, alpha-1C subunit

Gene Ontology (GO ID)

Biological Process

GO:0007628	adult walking behavior
GO:0070509	calcium ion import
GO:0070588	calcium ion transmembrane transport
GO:0006816	calcium ion transport
GO:0017156	calcium ion-dependent exocytosis
GO:0006874	cellular calcium ion homeostasis
GO:0007204	elevation of cytosolic calcium ion concentration
GO:0042593	glucose homeostasis
GO:0030252	growth hormone secretion
GO:0030073	insulin secretion
GO:0006811	ion transport
GO:0008217	regulation of blood pressure
GO:0034765	regulation of ion transmembrane transport
GO:0046620	regulation of organ growth
GO:0019229	regulation of vasoconstriction
GO:0006939	smooth muscle contraction
GO:0060083	smooth muscle contraction involved in micturition
GO:0007268	synaptic transmission
GO:0055085	transmembrane transport
GO:0006810	transport
GO:0008542	visual learning

Cellular Component

GO:0002095	caveolar macromolecular signaling complex
GO:0043025	cell soma
GO:0005737	cytoplasm
GO:0030425	dendrite
GO:0043198	dendritic shaft
GO:0016021	integral to membrane
GO:0016020	membrane
GO:0005634	nucleus
GO:0005886	plasma membrane
GO:0014069	postsynaptic density
GO:0042734	presynaptic membrane
GO:0043234	protein complex
GO:0042383	sarcolemma
GO:0030315	T-tubule
GO:0005891	voltage-gated calcium channel complex
GO:0030018	Z disc

Molecular Function

GO:0051393	alpha-actinin binding
GO:0005262	calcium channel activity
GO:0005516	calmodulin binding
GO:0008331	high voltage-gated calcium channel activity
GO:0005216	ion channel activity
GO:0046872	metal ion binding
GO:0005515	protein binding
GO:0019904	protein domain specific binding
GO:0051721	protein phosphatase 2A binding
GO:0005245	voltage-gated calcium channel activity
GO:0005244	voltage-gated ion channel activity

calcium channel, voltage-dependent, L type, alpha 1C subunit

Synonym

Expression Pattern

Choropleth map on BodyParts3D

Classification in 40 Organs

Gene Information

IDs

Orthologous Gene

Chromosomal Region

Gene Family (Interpro ID)

Link to Pubmed (Pubmed ID)

Gene Ontology (GO ID)

Biological Process

Cellular Component

Molecular Function