cadherin 13

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Synonym

Cdh13, 4932416G01Rik, Heart-cadherin, cadherin 13, T-cad, Cadherin-13 precursor, Cdht, Truncated-cadherin, H-cadherin, T-cadherin, Tcad

Expression Pattern

Choropleth map on BodyParts3D

Choropleth maps on 3D human body images were generated by the relative gene expression values measured by GeneChip.

Classification in 40 Organs

brain blood connective
EST cerebrum:114.60 cerebellum:165.80 brain stem:158.90 corpus callosum/glia:- pineal gland:- peripheral nerve:38.20 spine:331 retina:- eye:53.20 artery/aorta:843.90 vein:- lymphnode:- peripheral blood:28.80 spleen:13.20 thymus:69.20 bone marrow:- adipose:425.40 bone:25 skin:110.80
GeneChip cerebrum:5.80 cerebellum:3.98 brain stem:- corpus callosum/glia:- pineal gland:- peripheral nerve:3.99 spine:5.46 retina:3.68 eye:3.67 artery/aorta:- vein:4.23 lymphnode:3.72 peripheral blood:- spleen:3.72 thymus:- bone marrow:3.53 adipose:5.73 bone:3.72 skin:5.54
CAGE cerebrum:2.73 cerebellum:- brain stem:4.03 corpus callosum/glia:- pineal gland:- peripheral nerve:- spine:3.80 retina:- eye:- artery/aorta:4.70 vein:- lymphnode:2.11 peripheral blood:- spleen:0 thymus:0.95 bone marrow:- adipose:- bone:3.10 skin:4.36
RNA-seq cerebrum:11.13 cerebellum:- brain stem:- corpus callosum/glia:- pineal gland:- peripheral nerve:- spine:- retina:- eye:- artery/aorta:- vein:- lymphnode:- peripheral blood:- spleen:- thymus:- bone marrow:- adipose:- bone:- skin:-
reproductive muscular alimentary liver lung urinary endo/exo-crine
EST uterus:- placenta:- prostate:30.90 ovary:- testis:- heart:241.80 muscle:284.10 esophagus:- stomach:- intestine:- colon:17.60     liver/hepato:-        lung:40.20    bladder:198.50 kidney:- pituitary:38.80 thyroid/parathyroid:- adrenal gland:- pancreas:- breast:45.70 salivary:54
GeneChip uterus:4.27 placenta:4.58 prostate:4.48 ovary:4.25 testis:4.44 heart:7.04 muscle:8.11 esophagus:- stomach:4.38 intestine:4.14 colon:- liver/hepato:3.91 lung:5.47 bladder:5.32 kidney:4.09 pituitary:3.86 thyroid/parathyroid:- adrenal gland:3.71 pancreas:4.06 breast:6.53 salivary:3.71
CAGE uterus:2.91 placenta:3.15 prostate:3.06 ovary:2.47 testis:0 heart:- muscle:- esophagus:- stomach:2.60 intestine:1.43 colon:1.63     liver/hepato:1.75    lung:3.88 bladder:3.81 kidney:- pituitary:1.92 thyroid/parathyroid:- adrenal gland:2.20 pancreas:1.30 breast:3.92 salivary:-
RNA-seq uterus:- placenta:- prostate:- ovary:- testis:- heart:- muscle:6.58 esophagus:- stomach:- intestine:- colon:-     liver/hepato:1.32        lung:-    bladder:- kidney:- pituitary:- thyroid/parathyroid:- adrenal gland:- pancreas:- breast:- salivary:-

Gene Information

IDs

Refseq ID NM_019707
Gene ID 12554
Unigene ID Mm.334841
Probe set ID 1454015_a_at  [Mouse430_2]
Ensembl ID ENSMUSG00000031841

Orthologous Gene

Human[1]  NM_001220488, NM_001220489, NM_001220490, NM_001220491, NM_001220492, NM_001257
Rat[1]  NM_138889, NM_001220489, NM_001220490, NM_001220491, NM_001220492, NM_001257

Chromosomal Region

-

Gene Family (Interpro ID)

IPR002126  Cadherin
IPR015919  Cadherin-like

Link to Pubmed  (Pubmed ID)

8620560
8889548
9521872
10349636
10737605
11042159
11076861
11217851
12060406
12466851
12477932
12509455
12559965
14610273
14681479
15210937
15664173
16141072
16141073
16284245
16873731
17278136
17486418
17500595
17953485
18077674
18316604
18635739
19463088
19554387
19915153
20711475
20873143
21041950
21267068
21766307
21975561
22036570
22156343
22334647
22815927
23684624
23755285
23824191

Gene Ontology  (GO ID)

Biological Process

GO:0016339  calcium-dependent cell-cell adhesion
GO:0007155  cell adhesion
GO:0043542  endothelial cell migration
GO:0007156  homophilic cell adhesion
GO:0043616  keratinocyte proliferation
GO:0030032  lamellipodium assembly
GO:0051668  localization within membrane
GO:0055096  low-density lipoprotein mediated signaling
GO:0007162  negative regulation of cell adhesion
GO:0008285  negative regulation of cell proliferation
GO:0050850  positive regulation of calcium-mediated signaling
GO:0030335  positive regulation of cell migration
GO:0001954  positive regulation of cell-matrix adhesion
GO:0001938  positive regulation of endothelial cell proliferation
GO:0050927  positive regulation of positive chemotaxis
GO:0048661  positive regulation of smooth muscle cell proliferation
GO:0045944  positive regulation of transcription from RNA polymerase II promoter
GO:0016601  Rac protein signal transduction
GO:0001558  regulation of cell growth
GO:0030100  regulation of endocytosis
GO:0042058  regulation of epidermal growth factor receptor signaling pathway
GO:0007266  Rho protein signal transduction
GO:0002040  sprouting angiogenesis

Cellular Component

GO:0031225  anchored to membrane
GO:0005901  caveola
GO:0005737  cytoplasm
GO:0009897  external side of plasma membrane
GO:0005615  extracellular space
GO:0016021  integral to membrane
GO:0016020  membrane
GO:0043005  neuron projection
GO:0048471  perinuclear region of cytoplasm
GO:0005886  plasma membrane

Molecular Function

GO:0055100  adiponectin binding
GO:0045296  cadherin binding
GO:0005509  calcium ion binding
GO:0030169  low-density lipoprotein binding
GO:0046872  metal ion binding
GO:0005515  protein binding
GO:0042803  protein homodimerization activity