cyclin-dependent kinase inhibitor 1C (P57)

Synonym

Kip2, Cyclin-dependent kinase inhibitor 1C, p57KIP2, Cyclin-dependent kinase inhibitor p57, p57Kip2, p57(kip2), Cdkn1c, cyclin-dependent kinase inhibitor 1C (P57), CDKI, AL024410

normal 40 tissues
developmental tissues and primary cells（FANTOM5 CAGE）

Choropleth map on BodyParts3D

Choropleth maps on 3D human body images were generated by the relative gene expression values measured by GeneChip.

Classification in 40 Organs

brain

blood

connective

EST

cerebrum:69.50

cerebellum:-

brain stem:31.80

corpus callosum/glia:-

pineal gland:-

peripheral nerve:152.90

spine:283.70

retina:64.30

eye:91.20

artery/aorta:-

vein:-

lymphnode:-

peripheral blood:-

spleen:-

thymus:9.90

bone marrow:12.80

adipose:-

bone:325.60

skin:55.40

GeneChip

cerebrum:6.53

cerebellum:6.33

brain stem:-

corpus callosum/glia:-

pineal gland:-

peripheral nerve:7.18

spine:8.03

retina:7.98

eye:9.65

artery/aorta:-

vein:13.53

lymphnode:6.32

peripheral blood:-

spleen:5.70

thymus:-

bone marrow:6.33

adipose:8.66

bone:7.18

skin:7.64

CAGE

cerebrum:2.00

cerebellum:-

brain stem:1.59

corpus callosum/glia:-

pineal gland:-

peripheral nerve:-

spine:2.57

retina:-

eye:-

artery/aorta:2.76

vein:-

lymphnode:0.23

peripheral blood:-

spleen:0.16

thymus:1.26

bone marrow:-

adipose:-

bone:2.09

skin:1.81

RNA-seq

cerebrum:6.37

cerebellum:-

brain stem:-

corpus callosum/glia:-

pineal gland:-

peripheral nerve:-

spine:-

retina:-

eye:-

artery/aorta:-

vein:-

lymphnode:-

peripheral blood:-

spleen:-

thymus:-

bone marrow:-

adipose:-

bone:-

skin:-

reproductive

muscular

alimentary

liver

lung

urinary

endo/exo-crine

EST

uterus:654.40

placenta:234.70

prostate:92.60

ovary:91.90

testis:7.40

heart:148.80

muscle:-

esophagus:-

stomach:32.70

intestine:-

colon:35.20

liver/hepato:63.40

lung:40.20

bladder:-

kidney:88.70

pituitary:749.20

thyroid/parathyroid:-

adrenal gland:-

pancreas:347.10

breast:29.40

salivary:-

GeneChip

uterus:9.39

placenta:12.55

prostate:7.34

ovary:8.47

testis:9.35

heart:8.58

muscle:9.11

esophagus:-

stomach:8.65

intestine:6.78

colon:-

liver/hepato:6.06

lung:9.17

bladder:7.32

kidney:8

pituitary:7.52

thyroid/parathyroid:-

adrenal gland:10.13

pancreas:7.15

breast:9.12

salivary:7.89

CAGE

uterus:2.48

placenta:5.87

prostate:1.09

ovary:2.18

testis:1.18

heart:-

muscle:-

esophagus:-

stomach:3.13

intestine:1.36

colon:1.11

liver/hepato:1.02

lung:2.52

bladder:1.89

kidney:-

pituitary:2.45

thyroid/parathyroid:-

adrenal gland:4.11

pancreas:2.19

breast:2.06

salivary:-

RNA-seq

uterus:-

placenta:-

prostate:-

ovary:-

testis:-

heart:-

muscle:12.94

esophagus:-

stomach:-

intestine:-

colon:-

liver/hepato:2.01

lung:-

bladder:-

kidney:-

pituitary:-

thyroid/parathyroid:-

adrenal gland:-

pancreas:-

breast:-

salivary:-

IDs

Refseq ID	NM_001161624
Gene ID	12577
Unigene ID	Mm.168789
Probe set ID	1417649_at [Mouse430_2]
Ensembl ID	ENSMUSG00000037664

Orthologous Gene

Human[12]	NM_000076, NM_001122630, NM_001122631
Rat[1]	NM_001033757, NM_001122630, NM_001122631

Chromosomal Region

7F5 [150,644,255 - 150,646,955]

Search genes near this gene
- Between -5kb and +5kb
- Between -10kb and +10kb

Gene Family (Interpro ID)

Gene Ontology (GO ID)

Biological Process

GO:0007049	cell cycle
GO:0007050	cell cycle arrest
GO:0050680	negative regulation of epithelial cell proliferation
GO:0033673	negative regulation of kinase activity
GO:0042326	negative regulation of phosphorylation
GO:0000122	negative regulation of transcription from RNA polymerase II promoter
GO:0045892	negative regulation of transcription, DNA-dependent
GO:0042551	neuron maturation
GO:0016310	phosphorylation
GO:0001890	placenta development
GO:0045893	positive regulation of transcription, DNA-dependent
GO:0030511	positive regulation of transforming growth factor beta receptor signaling pathway

Cellular Component

GO:0005737	cytoplasm
GO:0005634	nucleus

Molecular Function

GO:0004861	cyclin-dependent protein kinase inhibitor activity
GO:0016301	kinase activity
GO:0005515	protein binding
GO:0004860	protein kinase inhibitor activity
GO:0016740	transferase activity

cyclin-dependent kinase inhibitor 1C (P57)

Synonym

Expression Pattern

Choropleth map on BodyParts3D

Classification in 40 Organs

Gene Information

IDs

Orthologous Gene

Chromosomal Region

Gene Family (Interpro ID)

Link to Pubmed (Pubmed ID)

Gene Ontology (GO ID)

Biological Process

Cellular Component

Molecular Function