ciliary neurotrophic factor

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Synonym

AI429687, Cntf, MGC41235, CNTF, ciliary neurotrophic factor, Ciliary neurotrophic factor

normal 40 tissues
developmental tissues and primary cells（FANTOM5 CAGE）

Choropleth map on BodyParts3D

Choropleth maps on 3D human body images were generated by the relative gene expression values measured by GeneChip.

Classification in 40 Organs

brain

blood

connective

EST

cerebrum:74.70

cerebellum:73.70

brain stem:31.80

corpus callosum/glia:-

pineal gland:257.80

peripheral nerve:38.20

spine:567.40

retina:64.30

eye:129.20

artery/aorta:337.60

vein:-

lymphnode:21.60

peripheral blood:115

spleen:79

thymus:217.40

bone marrow:12.80

adipose:-

bone:187.90

skin:47.50

GeneChip

cerebrum:6.01

cerebellum:6.67

brain stem:-

corpus callosum/glia:-

pineal gland:-

peripheral nerve:10.50

spine:8.03

retina:7.56

eye:8.54

artery/aorta:-

vein:6.13

lymphnode:6.37

peripheral blood:-

spleen:6.39

thymus:-

bone marrow:7.03

adipose:6.47

bone:6.75

skin:6.50

CAGE

cerebrum:0.49

cerebellum:-

brain stem:0.94

corpus callosum/glia:-

pineal gland:-

peripheral nerve:-

spine:2.36

retina:-

eye:-

artery/aorta:0.36

vein:-

lymphnode:0

peripheral blood:-

spleen:0.16

thymus:0

bone marrow:-

adipose:-

bone:0

skin:0.60

RNA-seq

cerebrum:8.44

cerebellum:-

brain stem:-

corpus callosum/glia:-

pineal gland:-

peripheral nerve:-

spine:-

retina:-

eye:-

artery/aorta:-

vein:-

lymphnode:-

peripheral blood:-

spleen:-

thymus:-

bone marrow:-

adipose:-

bone:-

skin:-

reproductive

muscular

alimentary

liver

lung

urinary

endo/exo-crine

EST

uterus:218.10

placenta:193.30

prostate:92.60

ovary:68.90

testis:103.50

heart:93

muscle:71

esophagus:-

stomach:32.70

intestine:-

colon:105.70

liver/hepato:36.20

lung:110.50

bladder:132.40

kidney:56.40

pituitary:77.50

thyroid/parathyroid:224.90

adrenal gland:-

pancreas:150.10

breast:202.40

salivary:-

GeneChip

uterus:6.01

placenta:6.23

prostate:5.87

ovary:6.25

testis:7.16

heart:6.38

muscle:6.75

esophagus:-

stomach:6.30

intestine:6.44

colon:-

liver/hepato:6.38

lung:5.72

bladder:5.90

kidney:6.57

pituitary:6.34

thyroid/parathyroid:-

adrenal gland:6.32

pancreas:6.52

breast:6.48

salivary:5.96

CAGE

uterus:0.17

placenta:0.87

prostate:0.51

ovary:0.88

testis:0

heart:-

muscle:-

esophagus:-

stomach:0.67

intestine:0.23

colon:0.23

liver/hepato:0

lung:0

bladder:0.77

kidney:-

pituitary:0

thyroid/parathyroid:-

adrenal gland:0.56

pancreas:0

breast:0.12

salivary:-

RNA-seq

uterus:-

placenta:-

prostate:-

ovary:-

testis:-

heart:-

muscle:4.73

esophagus:-

stomach:-

intestine:-

colon:-

liver/hepato:6.10

lung:-

bladder:-

kidney:-

pituitary:-

thyroid/parathyroid:-

adrenal gland:-

pancreas:-

breast:-

salivary:-

IDs

Refseq ID	NM_170786
Gene ID	12803
Unigene ID	Mm.290924
Probe set ID	1422033_a_at [Mouse430_2]
Ensembl ID	ENSMUSG00000079415

Orthologous Gene

Human[1]	NM_000614
Rat [0]

Chromosomal Region

Gene Family (Interpro ID)

Gene Ontology (GO ID)

Biological Process

GO:0048143	astrocyte activation
GO:0030154	cell differentiation
GO:0070120	ciliary neurotrophic factor-mediated signaling pathway
GO:0040007	growth
GO:0007259	JAK-STAT cascade
GO:0060081	membrane hyperpolarization
GO:0007275	multicellular organismal development
GO:0048644	muscle organ morphogenesis
GO:0043524	negative regulation of neuron apoptosis
GO:0046533	negative regulation of photoreceptor cell differentiation
GO:0007399	nervous system development
GO:0048666	neuron development
GO:0048680	positive regulation of axon regeneration
GO:0030307	positive regulation of cell growth
GO:0008284	positive regulation of cell proliferation
GO:0046887	positive regulation of hormone secretion
GO:0046427	positive regulation of JAK-STAT cascade
GO:0043410	positive regulation of MAPKKK cascade
GO:0014068	positive regulation of phosphoinositide 3-kinase cascade
GO:0042517	positive regulation of tyrosine phosphorylation of Stat3 protein
GO:0051291	protein heterooligomerization
GO:0060075	regulation of resting membrane potential
GO:0046668	regulation of retinal cell programmed cell death

Cellular Component

GO:0030424	axon
GO:0032838	cell projection cytoplasm
GO:0043025	cell soma
GO:0005737	cytoplasm
GO:0005829	cytosol
GO:0005615	extracellular space
GO:0043231	intracellular membrane-bounded organelle
GO:0005634	nucleus

Molecular Function

GO:0005127	ciliary neurotrophic factor receptor binding
GO:0005125	cytokine activity
GO:0008083	growth factor activity
GO:0005138	interleukin-6 receptor binding

ciliary neurotrophic factor

Synonym

Expression Pattern

Choropleth map on BodyParts3D

Classification in 40 Organs

Gene Information

IDs

Orthologous Gene

Chromosomal Region

Gene Family (Interpro ID)

Link to Pubmed (Pubmed ID)

Gene Ontology (GO ID)

Biological Process

Cellular Component

Molecular Function