corticotropin releasing hormone

Synonym

Gm1347, Crh, Corticoliberin precursor, Corticotropin-releasing factor, Corticotropin-releasing hormone, CRF, corticotropin releasing hormone, corticotropin releasing factor, MGC151298

normal 40 tissues
developmental tissues and primary cells（FANTOM5 CAGE）

Choropleth map on BodyParts3D

Choropleth maps on 3D human body images were generated by the relative gene expression values measured by GeneChip.

Classification in 40 Organs

brain

blood

connective

EST

cerebrum:10.40

cerebellum:-

brain stem:63.60

corpus callosum/glia:-

pineal gland:-

peripheral nerve:-

spine:-

retina:-

eye:-

artery/aorta:-

vein:-

lymphnode:-

peripheral blood:-

spleen:-

thymus:-

bone marrow:-

adipose:-

bone:-

skin:-

GeneChip

nodata

CAGE

cerebrum:0.41

cerebellum:-

brain stem:1.90

corpus callosum/glia:-

pineal gland:-

peripheral nerve:-

spine:0.44

retina:-

eye:-

artery/aorta:0

vein:-

lymphnode:0

peripheral blood:-

spleen:0

thymus:0

bone marrow:-

adipose:-

bone:0

skin:0

RNA-seq

cerebrum:1.52

cerebellum:-

brain stem:-

corpus callosum/glia:-

pineal gland:-

peripheral nerve:-

spine:-

retina:-

eye:-

artery/aorta:-

vein:-

lymphnode:-

peripheral blood:-

spleen:-

thymus:-

bone marrow:-

adipose:-

bone:-

skin:-

reproductive

muscular

alimentary

liver

lung

urinary

endo/exo-crine

EST

uterus:-

placenta:-

prostate:-

ovary:-

testis:-

heart:-

muscle:-

esophagus:-

stomach:-

intestine:-

colon:-

liver/hepato:-

lung:-

bladder:-

kidney:-

pituitary:-

thyroid/parathyroid:-

adrenal gland:-

pancreas:-

breast:-

salivary:-

GeneChip

nodata

CAGE

uterus:0

placenta:0

prostate:0

ovary:0

testis:0

heart:-

muscle:-

esophagus:-

stomach:0

intestine:0

colon:0

liver/hepato:0

lung:0

bladder:0

kidney:-

pituitary:0

thyroid/parathyroid:-

adrenal gland:0

pancreas:0

breast:0

salivary:-

RNA-seq

uterus:-

placenta:-

prostate:-

ovary:-

testis:-

heart:-

muscle:0.71

esophagus:-

stomach:-

intestine:-

colon:-

liver/hepato:0

lung:-

bladder:-

kidney:-

pituitary:-

thyroid/parathyroid:-

adrenal gland:-

pancreas:-

breast:-

salivary:-

IDs

Refseq ID	NM_205769
Gene ID	12918
Unigene ID	Mm.290689
Probe set ID	-
Ensembl ID	ENSMUSG00000049796

Orthologous Gene

Human[2]	NM_000756
Rat [0]

Chromosomal Region

3A2 [19,593,401 - 19,595,396]

Search genes near this gene
- Between -5kb and +5kb
- Between -10kb and +10kb

Gene Family (Interpro ID)

IPR000187

Corticotropin-releasing factor, CRF

Gene Ontology (GO ID)

Biological Process

GO:0030325	adrenal gland development
GO:0008306	associative learning
GO:0071314	cellular response to cocaine
GO:0007631	feeding behavior
GO:0007565	female pregnancy
GO:0006704	glucocorticoid biosynthetic process
GO:0008628	induction of apoptosis by hormones
GO:0006954	inflammatory response
GO:0007611	learning or memory
GO:0007616	long-term memory
GO:0060291	long-term synaptic potentiation
GO:0030324	lung development
GO:0045776	negative regulation of blood pressure
GO:0060548	negative regulation of cell death
GO:0032811	negative regulation of epinephrine secretion
GO:0010629	negative regulation of gene expression
GO:0070093	negative regulation of glucagon secretion
GO:0033685	negative regulation of luteinizing hormone secretion
GO:0010700	negative regulation of norepinephrine secretion
GO:0051461	positive regulation of adrenocorticotropin secretion
GO:0030819	positive regulation of cAMP biosynthetic process
GO:0010942	positive regulation of cell death
GO:0008284	positive regulation of cell proliferation
GO:0051464	positive regulation of cortisol secretion
GO:0060456	positive regulation of digestive system process
GO:0010628	positive regulation of gene expression
GO:0001934	positive regulation of protein amino acid phosphorylation
GO:0014062	regulation of serotonin secretion
GO:0006950	response to stress
GO:0001963	synaptic transmission, dopaminergic

Cellular Component

GO:0043025	cell soma
GO:0005737	cytoplasm
GO:0005576	extracellular region
GO:0005615	extracellular space
GO:0043204	perikaryon
GO:0043196	varicosity

Molecular Function

GO:0017045	adrenocorticotropin-releasing hormone activity
GO:0051430	corticotropin-releasing hormone receptor 1 binding
GO:0051431	corticotropin-releasing hormone receptor 2 binding
GO:0005179	hormone activity
GO:0005102	receptor binding

corticotropin releasing hormone

Synonym

Expression Pattern

Choropleth map on BodyParts3D

Classification in 40 Organs

Gene Information

IDs

Orthologous Gene

Chromosomal Region

Gene Family (Interpro ID)

Link to Pubmed (Pubmed ID)

Gene Ontology (GO ID)

Biological Process

Cellular Component

Molecular Function