cytochrome P450, family 11, subfamily a, polypeptide 1

Synonym

Cyp11a, Cholesterol desmolase, CYPXIA1, Cholesterol side-chain cleavage enzyme, Cypxia1, D9Ertd411e, Cyp11a1, P450(scc), Cytochrome P450 11A1, mitochondrial precursor, Scc, cholesterol side chain cleavage, P450scc

normal 40 tissues
developmental tissues and primary cells（FANTOM5 CAGE）

Choropleth map on BodyParts3D

Choropleth maps on 3D human body images were generated by the relative gene expression values measured by GeneChip.

Classification in 40 Organs

brain

blood

connective

EST

cerebrum:12.20

cerebellum:55.30

brain stem:95.30

corpus callosum/glia:-

pineal gland:-

peripheral nerve:-

spine:-

retina:-

eye:-

artery/aorta:-

vein:-

lymphnode:-

peripheral blood:43.10

spleen:26.30

thymus:-

bone marrow:12.80

adipose:-

bone:-

skin:7.90

GeneChip

cerebrum:4.68

cerebellum:4.55

brain stem:-

corpus callosum/glia:-

pineal gland:-

peripheral nerve:5.05

spine:4.36

retina:4.06

eye:4.26

artery/aorta:-

vein:4.72

lymphnode:4.14

peripheral blood:-

spleen:4.52

thymus:-

bone marrow:4.66

adipose:4.71

bone:5.57

skin:4.57

CAGE

cerebrum:0

cerebellum:-

brain stem:0

corpus callosum/glia:-

pineal gland:-

peripheral nerve:-

spine:0

retina:-

eye:-

artery/aorta:0.46

vein:-

lymphnode:0.71

peripheral blood:-

spleen:0.29

thymus:0

bone marrow:-

adipose:-

bone:1.02

skin:0.77

RNA-seq

cerebrum:1.06

cerebellum:-

brain stem:-

corpus callosum/glia:-

pineal gland:-

peripheral nerve:-

spine:-

retina:-

eye:-

artery/aorta:-

vein:-

lymphnode:-

peripheral blood:-

spleen:-

thymus:-

bone marrow:-

adipose:-

bone:-

skin:-

reproductive

muscular

alimentary

liver

lung

urinary

endo/exo-crine

EST

uterus:-

placenta:248.50

prostate:-

ovary:114.90

testis:81.30

heart:-

muscle:-

esophagus:-

stomach:-

intestine:-

colon:-

liver/hepato:-

lung:-

bladder:-

kidney:-

pituitary:-

thyroid/parathyroid:-

adrenal gland:424.40

pancreas:-

breast:3.30

salivary:-

GeneChip

uterus:4.30

placenta:9.95

prostate:4.80

ovary:14.13

testis:9.64

heart:4.45

muscle:4.72

esophagus:-

stomach:4.17

intestine:4.14

colon:-

liver/hepato:4.45

lung:4.26

bladder:4.40

kidney:4.21

pituitary:4.71

thyroid/parathyroid:-

adrenal gland:13.13

pancreas:4.72

breast:6.05

salivary:4.29

CAGE

uterus:2.99

placenta:5.57

prostate:0

ovary:7.98

testis:5.58

heart:-

muscle:-

esophagus:-

stomach:1.07

intestine:0.42

colon:0

liver/hepato:0

lung:0.44

bladder:0.18

kidney:-

pituitary:0

thyroid/parathyroid:-

adrenal gland:8.42

pancreas:0

breast:0.22

salivary:-

RNA-seq

uterus:-

placenta:-

prostate:-

ovary:-

testis:-

heart:-

muscle:2.07

esophagus:-

stomach:-

intestine:-

colon:-

liver/hepato:0

lung:-

bladder:-

kidney:-

pituitary:-

thyroid/parathyroid:-

adrenal gland:-

pancreas:-

breast:-

salivary:-

IDs

Refseq ID	NM_019779
Gene ID	13070
Unigene ID	Mm.302865
Probe set ID	1448804_at [Mouse430_2]
Ensembl ID	ENSMUSG00000032323

Orthologous Gene

Human[2]	NM_000781, NM_001099773
Rat [0]

Chromosomal Region

Gene Family (Interpro ID)

IPR001128	Cytochrome P450
IPR002397	Cytochrome P450, B-class
IPR002401	Cytochrome P450, E-class, group I
IPR002403	Cytochrome P450, E-class, group IV

Gene Ontology (GO ID)

Biological Process

GO:0006700	C21-steroid hormone biosynthetic process
GO:0008203	cholesterol metabolic process
GO:0006629	lipid metabolic process
GO:0007617	mating behavior
GO:0055114	oxidation reduction
GO:0042542	response to hydrogen peroxide
GO:0006694	steroid biosynthetic process
GO:0008202	steroid metabolic process

Cellular Component

GO:0016020	membrane
GO:0030061	mitochondrial crista
GO:0005743	mitochondrial inner membrane
GO:0005739	mitochondrion
GO:0043204	perikaryon

Molecular Function

GO:0015485	cholesterol binding
GO:0008386	cholesterol monooxygenase (side-chain-cleaving) activity
GO:0009055	electron carrier activity
GO:0020037	heme binding
GO:0005506	iron ion binding
GO:0046872	metal ion binding
GO:0004497	monooxygenase activity
GO:0016491	oxidoreductase activity
GO:0016705	oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen

cytochrome P450, family 11, subfamily a, polypeptide 1

Synonym

Expression Pattern

Choropleth map on BodyParts3D

Classification in 40 Organs

Gene Information

IDs

Orthologous Gene

Chromosomal Region

Gene Family (Interpro ID)

Link to Pubmed (Pubmed ID)

Gene Ontology (GO ID)

Biological Process

Cellular Component

Molecular Function