cytochrome P450, family 3, subfamily a, polypeptide 13

 jump to detail

Synonym

Cyp3a13, CYPIIIA13, Cytochrome P450 3A13, IIIAm2, Cyp3a-13

Expression Pattern

Choropleth map on BodyParts3D

Choropleth maps on 3D human body images were generated by the relative gene expression values measured by GeneChip.

Classification in 40 Organs

brain blood connective
EST cerebrum:- cerebellum:- brain stem:- corpus callosum/glia:- pineal gland:- peripheral nerve:- spine:- retina:- eye:7.60 artery/aorta:- vein:- lymphnode:- peripheral blood:- spleen:- thymus:- bone marrow:- adipose:- bone:- skin:87.10
GeneChip cerebrum:3.85 cerebellum:3.93 brain stem:- corpus callosum/glia:- pineal gland:- peripheral nerve:3.74 spine:4.30 retina:3.74 eye:5.41 artery/aorta:- vein:3.93 lymphnode:3.55 peripheral blood:- spleen:3.86 thymus:- bone marrow:3.86 adipose:3.83 bone:3.78 skin:5.39
CAGE cerebrum:0 cerebellum:- brain stem:0 corpus callosum/glia:- pineal gland:- peripheral nerve:- spine:0 retina:- eye:- artery/aorta:0.62 vein:- lymphnode:0 peripheral blood:- spleen:0 thymus:0 bone marrow:- adipose:- bone:0 skin:1.15
RNA-seq cerebrum:1.88 cerebellum:- brain stem:- corpus callosum/glia:- pineal gland:- peripheral nerve:- spine:- retina:- eye:- artery/aorta:- vein:- lymphnode:- peripheral blood:- spleen:- thymus:- bone marrow:- adipose:- bone:- skin:-
reproductive muscular alimentary liver lung urinary endo/exo-crine
EST uterus:- placenta:- prostate:- ovary:- testis:- heart:- muscle:- esophagus:- stomach:- intestine:37 colon:123.40     liver/hepato:81.50        lung:-    bladder:- kidney:8.10 pituitary:- thyroid/parathyroid:- adrenal gland:- pancreas:- breast:3.30 salivary:-
GeneChip uterus:3.97 placenta:4.67 prostate:3.65 ovary:3.83 testis:3.78 heart:3.94 muscle:4.43 esophagus:- stomach:9.73 intestine:10.50 colon:- liver/hepato:9.96 lung:5.13 bladder:3.96 kidney:3.98 pituitary:3.76 thyroid/parathyroid:- adrenal gland:3.92 pancreas:4.81 breast:3.70 salivary:4.08
CAGE uterus:0.44 placenta:0.10 prostate:0.20 ovary:0.45 testis:0 heart:- muscle:- esophagus:- stomach:3.45 intestine:5.04 colon:6.07     liver/hepato:5.37    lung:1.33 bladder:0.33 kidney:- pituitary:0 thyroid/parathyroid:- adrenal gland:0.97 pancreas:2.33 breast:0.12 salivary:-
RNA-seq uterus:- placenta:- prostate:- ovary:- testis:- heart:- muscle:- esophagus:- stomach:- intestine:- colon:-     liver/hepato:32.56        lung:-    bladder:- kidney:- pituitary:- thyroid/parathyroid:- adrenal gland:- pancreas:- breast:- salivary:-

Gene Information

IDs

Refseq ID NM_007819
Gene ID 13113
Unigene ID Mm.289886
Probe set ID 1419523_at  [Mouse430_2]
Ensembl ID ENSMUSG00000029727

Orthologous Gene

Human[19]  NM_022820, NM_057095, NM_057096, NM_000777, NM_001190484, NM_001202855, NM_017460, NM_000765
Rat[3]  NM_145782, NM_153312, NM_147206, NM_013105, NM_001190484, NM_001202855, NM_017460, NM_000765

Chromosomal Region

-

Gene Family (Interpro ID)

IPR001128  Cytochrome P450
IPR002397  Cytochrome P450, B-class
IPR008072  Cytochrome P450, E-class, CYP3A
IPR002401  Cytochrome P450, E-class, group I
IPR002402  Cytochrome P450, E-class, group II
IPR002403  Cytochrome P450, E-class, group IV

Link to Pubmed  (Pubmed ID)

7678494
7803471
7813478
10349636
10464095
11042159
11076861
11217851
12466851
12477932
12745259
12958193
12964049
14509827
14610273
14681479
15489334
15533722
16141072
16141073
17975676
18794335
19920203
21193583
21267068
21677750
23125282
23656416
23709690

Gene Ontology  (GO ID)

Biological Process

GO:0055114  oxidation reduction
GO:0010628  positive regulation of gene expression

Cellular Component

GO:0005783  endoplasmic reticulum
GO:0043231  intracellular membrane-bounded organelle
GO:0016020  membrane

Molecular Function

GO:0070330  aromatase activity
GO:0009055  electron carrier activity
GO:0020037  heme binding
GO:0005506  iron ion binding
GO:0046872  metal ion binding
GO:0004497  monooxygenase activity
GO:0016491  oxidoreductase activity
GO:0016705  oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen
GO:0016712  oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, reduced flavin or flavoprotein as one donor, and incorporation of one atom of oxygen