disabled homolog 1 (Drosophila)

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Synonym

scm, scr, disabled homolog 1 (Drosophila), Dab1, Disabled homolog 1, yot, AI956902, scrambler, C630028C02Rik

normal 40 tissues
developmental tissues and primary cells（FANTOM5 CAGE）

Choropleth map on BodyParts3D

Choropleth maps on 3D human body images were generated by the relative gene expression values measured by GeneChip.

Classification in 40 Organs

brain

blood

connective

EST

cerebrum:95.50

cerebellum:73.70

brain stem:190.70

corpus callosum/glia:-

pineal gland:-

peripheral nerve:38.20

spine:-

retina:64.30

eye:76

artery/aorta:-

vein:-

lymphnode:-

peripheral blood:-

spleen:52.70

thymus:-

bone marrow:-

adipose:-

bone:-

skin:-

GeneChip

cerebrum:8.14

cerebellum:8.10

brain stem:-

corpus callosum/glia:-

pineal gland:-

peripheral nerve:4.58

spine:7.19

retina:7.73

eye:5.83

artery/aorta:-

vein:4.41

lymphnode:4.13

peripheral blood:-

spleen:4.22

thymus:-

bone marrow:4.30

adipose:4.09

bone:4.28

skin:6.82

CAGE

cerebrum:4.67

cerebellum:-

brain stem:3.47

corpus callosum/glia:-

pineal gland:-

peripheral nerve:-

spine:3.50

retina:-

eye:-

artery/aorta:0

vein:-

lymphnode:0.83

peripheral blood:-

spleen:0.16

thymus:0

bone marrow:-

adipose:-

bone:0

skin:2.78

RNA-seq

cerebrum:4.40

cerebellum:-

brain stem:-

corpus callosum/glia:-

pineal gland:-

peripheral nerve:-

spine:-

retina:-

eye:-

artery/aorta:-

vein:-

lymphnode:-

peripheral blood:-

spleen:-

thymus:-

bone marrow:-

adipose:-

bone:-

skin:-

reproductive

muscular

alimentary

liver

lung

urinary

endo/exo-crine

EST

uterus:-

placenta:-

prostate:-

ovary:23

testis:7.40

heart:-

muscle:-

esophagus:-

stomach:-

intestine:332.80

colon:-

liver/hepato:-

lung:-

bladder:-

kidney:24.20

pituitary:-

thyroid/parathyroid:-

adrenal gland:-

pancreas:-

breast:-

salivary:-

GeneChip

uterus:5.63

placenta:4.36

prostate:4.79

ovary:4.35

testis:4.62

heart:4.64

muscle:4.75

esophagus:-

stomach:4.73

intestine:6.09

colon:-

liver/hepato:4.85

lung:3.99

bladder:4.41

kidney:4.70

pituitary:4

thyroid/parathyroid:-

adrenal gland:4.26

pancreas:4.74

breast:4.09

salivary:4.33

CAGE

uterus:2.26

placenta:1.08

prostate:0.84

ovary:1.14

testis:1.71

heart:-

muscle:-

esophagus:-

stomach:1.57

intestine:1.75

colon:1.81

liver/hepato:0

lung:0.17

bladder:1.20

kidney:-

pituitary:0.52

thyroid/parathyroid:-

adrenal gland:1.58

pancreas:0

breast:0

salivary:-

RNA-seq

uterus:-

placenta:-

prostate:-

ovary:-

testis:-

heart:-

muscle:0.95

esophagus:-

stomach:-

intestine:-

colon:-

liver/hepato:0.96

lung:-

bladder:-

kidney:-

pituitary:-

thyroid/parathyroid:-

adrenal gland:-

pancreas:-

breast:-

salivary:-

IDs

Refseq ID	NM_177259
Gene ID	13131
Unigene ID	Mm.289682
Probe set ID	1435578_s_at [Mouse430_2]
Ensembl ID	ENSMUSG00000028519

Orthologous Gene

Human[1]	NM_021080
Rat[1]	NM_153621

Chromosomal Region

Gene Family (Interpro ID)

IPR006020	Phosphotyrosine interaction domain
IPR011993	Pleckstrin homology-type

Gene Ontology (GO ID)

Biological Process

GO:0007628	adult walking behavior
GO:0030154	cell differentiation
GO:0021813	cell-cell adhesion involved in neuronal-glial interactions involved in cerebral cortex radial glia guided migration
GO:0007417	central nervous system development
GO:0021589	cerebellum structural organization
GO:0021795	cerebral cortex cell migration
GO:0021799	cerebral cortex radially oriented cell migration
GO:0016358	dendrite development
GO:0051645	Golgi localization
GO:0007275	multicellular organismal development
GO:0048712	negative regulation of astrocyte differentiation
GO:0050771	negative regulation of axonogenesis
GO:0007162	negative regulation of cell adhesion
GO:0046426	negative regulation of JAK-STAT cascade
GO:0007399	nervous system development
GO:0001764	neuron migration
GO:0045666	positive regulation of neuron differentiation
GO:0045860	positive regulation of protein kinase activity
GO:0007243	protein kinase cascade
GO:0021942	radial glia guided migration of Purkinje cell
GO:0007264	small GTPase mediated signal transduction

Cellular Component

GO:0045177	apical part of cell
GO:0005903	brush border
GO:0043025	cell soma
GO:0005829	cytosol
GO:0005622	intracellular
GO:0016020	membrane
GO:0043005	neuron projection
GO:0048471	perinuclear region of cytoplasm
GO:0014069	postsynaptic density

Molecular Function

GO:0043548	phosphoinositide 3-kinase binding
GO:0005543	phospholipid binding
GO:0005515	protein binding
GO:0042169	SH2 domain binding

disabled homolog 1 (Drosophila)

Synonym

Expression Pattern

Choropleth map on BodyParts3D

Classification in 40 Organs

Gene Information

IDs

Orthologous Gene

Chromosomal Region

Gene Family (Interpro ID)

Link to Pubmed (Pubmed ID)

Gene Ontology (GO ID)

Biological Process

Cellular Component

Molecular Function