drebrin-like

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Synonym

mAbp1, Actin-binding protein 1, Dbnl, SH3P7, drebrin-like, SH3 domain-containing protein 7, Drebrin-like protein, Abp1, Sh3p7

Expression Pattern

Choropleth map on BodyParts3D

Choropleth maps on 3D human body images were generated by the relative gene expression values measured by GeneChip.

Classification in 40 Organs

brain blood connective
EST cerebrum:165 cerebellum:36.80 brain stem:286 corpus callosum/glia:- pineal gland:- peripheral nerve:19.10 spine:47.30 retina:128.60 eye:91.20 artery/aorta:- vein:- lymphnode:151.20 peripheral blood:43.10 spleen:237 thymus:88.90 bone marrow:294.90 adipose:- bone:238 skin:142.50
GeneChip cerebrum:8.16 cerebellum:7.78 brain stem:- corpus callosum/glia:- pineal gland:- peripheral nerve:8.70 spine:8.51 retina:6.65 eye:8.02 artery/aorta:- vein:8.15 lymphnode:10.17 peripheral blood:- spleen:10.04 thymus:- bone marrow:9.40 adipose:7.96 bone:8.70 skin:8.62
CAGE cerebrum:3.87 cerebellum:- brain stem:4.29 corpus callosum/glia:- pineal gland:- peripheral nerve:- spine:4.22 retina:- eye:- artery/aorta:3.85 vein:- lymphnode:5.08 peripheral blood:- spleen:4.46 thymus:4.45 bone marrow:- adipose:- bone:4.81 skin:4.39
RNA-seq cerebrum:11.29 cerebellum:- brain stem:- corpus callosum/glia:- pineal gland:- peripheral nerve:- spine:- retina:- eye:- artery/aorta:- vein:- lymphnode:- peripheral blood:- spleen:- thymus:- bone marrow:- adipose:- bone:- skin:-
reproductive muscular alimentary liver lung urinary endo/exo-crine
EST uterus:130.90 placenta:207.10 prostate:30.90 ovary:23 testis:22.20 heart:55.80 muscle:- esophagus:- stomach:32.70 intestine:- colon:52.90     liver/hepato:54.30        lung:160.70    bladder:132.40 kidney:72.50 pituitary:142.10 thyroid/parathyroid:- adrenal gland:- pancreas:56.30 breast:81.60 salivary:162
GeneChip uterus:8.91 placenta:9.28 prostate:8.19 ovary:8.33 testis:8.03 heart:7.37 muscle:7.21 esophagus:- stomach:9 intestine:9.15 colon:- liver/hepato:7.71 lung:8.67 bladder:8.70 kidney:8.21 pituitary:8.23 thyroid/parathyroid:- adrenal gland:7.65 pancreas:6.97 breast:8.13 salivary:7.39
CAGE uterus:4.32 placenta:4.80 prostate:3.87 ovary:4.01 testis:4.13 heart:- muscle:- esophagus:- stomach:4.42 intestine:4.78 colon:4.78     liver/hepato:3.58    lung:4.41 bladder:4.49 kidney:- pituitary:4.09 thyroid/parathyroid:- adrenal gland:4.02 pancreas:3.57 breast:3.96 salivary:-
RNA-seq uterus:- placenta:- prostate:- ovary:- testis:- heart:- muscle:2.95 esophagus:- stomach:- intestine:- colon:-     liver/hepato:9.78        lung:-    bladder:- kidney:- pituitary:- thyroid/parathyroid:- adrenal gland:- pancreas:- breast:- salivary:-

Gene Information

IDs

Refseq ID NM_001146309
Gene ID 13169
Unigene ID Mm.256925
Probe set ID 1460334_at  [Mouse430_2]
Ensembl ID ENSMUSG00000020476

Orthologous Gene

Human[3]  NM_001014436, NM_001122956, NM_014063
Rat [0]  

Chromosomal Region

11A1  [5,688,491  -  5,700,965]

Gene Family (Interpro ID)

IPR002108  Actin-binding, cofilin/tropomyosin type

Link to Pubmed  (Pubmed ID)

9126384
9630982
9891087
10087302
10349636
10613908
10637315
10922068
11042159
11076861
11217851
11544199
12466851
12477932
12520002
12913069
14729663
15489334
15782199
15848169
16055701
16141072
16141073
16601697
16602821
16944949
17956734
18453588
18799693
18829961
19064729
19208628
19638624
19910490
21267068
21565611
21677750
22303001
22450813
22922362
23223303

Gene Ontology  (GO ID)

Biological Process

GO:0051017  actin filament bundle formation
GO:0051014  actin filament severing
GO:0051016  barbed-end actin filament capping
GO:0006897  endocytosis
GO:0048812  neuron projection morphogenesis
GO:0016601  Rac protein signal transduction
GO:0007416  synapse assembly
GO:0006810  transport

Cellular Component

GO:0005938  cell cortex
GO:0030054  cell junction
GO:0042995  cell projection
GO:0005737  cytoplasm
GO:0031410  cytoplasmic vesicle
GO:0005856  cytoskeleton
GO:0030425  dendrite
GO:0005794  Golgi apparatus
GO:0005622  intracellular
GO:0030027  lamellipodium
GO:0016020  membrane
GO:0005886  plasma membrane
GO:0002102  podosome
GO:0014069  postsynaptic density
GO:0001726  ruffle
GO:0045202  synapse

Molecular Function

GO:0003779  actin binding
GO:0051015  actin filament binding
GO:0005515  protein binding
GO:0008022  protein C-terminus binding
GO:0019904  protein domain specific binding