Eph receptor A5

 jump to detail

Synonym

Cek7, AI854630, Ephrin type-A receptor 5 precursor, Eph receptor A5, Els1, Brain-specific kinase, bsk, Rek7, EPH homology kinase 1, Epha5, Ehk1, Tyrosine-protein kinase receptor EHK-1, Bsk, Hek7, CEK-7

Expression Pattern

Choropleth map on BodyParts3D

Choropleth maps on 3D human body images were generated by the relative gene expression values measured by GeneChip.

Classification in 40 Organs

brain blood connective
EST cerebrum:85.10 cerebellum:92.10 brain stem:31.80 corpus callosum/glia:- pineal gland:- peripheral nerve:133.80 spine:94.60 retina:64.30 eye:60.80 artery/aorta:- vein:- lymphnode:- peripheral blood:- spleen:- thymus:- bone marrow:- adipose:- bone:- skin:23.80
GeneChip cerebrum:4.65 cerebellum:3.91 brain stem:- corpus callosum/glia:- pineal gland:- peripheral nerve:3.73 spine:4.04 retina:4.67 eye:4.66 artery/aorta:- vein:3.89 lymphnode:3.63 peripheral blood:- spleen:3.86 thymus:- bone marrow:3.97 adipose:3.61 bone:3.96 skin:3.89
CAGE cerebrum:3.07 cerebellum:- brain stem:3.42 corpus callosum/glia:- pineal gland:- peripheral nerve:- spine:3.15 retina:- eye:- artery/aorta:0.14 vein:- lymphnode:0 peripheral blood:- spleen:0 thymus:0 bone marrow:- adipose:- bone:0 skin:0
RNA-seq cerebrum:2.70 cerebellum:- brain stem:- corpus callosum/glia:- pineal gland:- peripheral nerve:- spine:- retina:- eye:- artery/aorta:- vein:- lymphnode:- peripheral blood:- spleen:- thymus:- bone marrow:- adipose:- bone:- skin:-
reproductive muscular alimentary liver lung urinary endo/exo-crine
EST uterus:- placenta:- prostate:- ovary:- testis:7.40 heart:- muscle:- esophagus:- stomach:- intestine:- colon:-     liver/hepato:-        lung:-    bladder:- kidney:- pituitary:25.80 thyroid/parathyroid:- adrenal gland:- pancreas:- breast:- salivary:-
GeneChip uterus:3.68 placenta:3.81 prostate:3.79 ovary:3.70 testis:3.84 heart:3.64 muscle:3.75 esophagus:- stomach:3.85 intestine:3.77 colon:- liver/hepato:4.28 lung:3.73 bladder:3.80 kidney:3.71 pituitary:3.85 thyroid/parathyroid:- adrenal gland:3.91 pancreas:3.94 breast:3.89 salivary:4.53
CAGE uterus:0.17 placenta:0.11 prostate:0.37 ovary:0.99 testis:0 heart:- muscle:- esophagus:- stomach:0 intestine:0 colon:0.41     liver/hepato:0    lung:0 bladder:0.57 kidney:- pituitary:2.71 thyroid/parathyroid:- adrenal gland:1.42 pancreas:2.03 breast:0 salivary:-
RNA-seq uterus:- placenta:- prostate:- ovary:- testis:- heart:- muscle:0.74 esophagus:- stomach:- intestine:- colon:-     liver/hepato:0        lung:-    bladder:- kidney:- pituitary:- thyroid/parathyroid:- adrenal gland:- pancreas:- breast:- salivary:-

Gene Information

IDs

Refseq ID NM_007937
Gene ID 13839
Unigene ID Mm.137991
Probe set ID 1420557_at  [Mouse430_2]
Ensembl ID ENSMUSG00000029245

Orthologous Gene

Human[2]  NM_004439, NM_182472
Rat [0]  

Chromosomal Region

-

Gene Family (Interpro ID)

IPR001090  Ephrin receptor, ligand binding
IPR003961  Fibronectin, type III
IPR008957  Fibronectin, type III-like fold
IPR008979  Galactose-binding domain-like
IPR000719  Protein kinase, catalytic domain
IPR011009  Protein kinase-like domain
IPR002290  Serine/threonine-protein kinase domain
IPR017442  Serine/threonine-protein kinase-like domain
IPR001660  Sterile alpha motif
IPR010993  Sterile alpha motif homology
IPR013761  Sterile alpha motif-type
IPR020685  Tyrosine-protein kinase
IPR001245  Tyrosine-protein kinase, catalytic domain
IPR016257  Tyrosine-protein kinase, ephrin receptor
IPR020933  Tyrosine-protein kinase, fibroblast growth factor receptor, conserved region
IPR020635  Tyrosine-protein kinase, subgroup, catalytic domain

Link to Pubmed  (Pubmed ID)

8145300
8152808
8507985
8703124
8755474
8889548
9221918
9267020
9614241
9883724
10349636
10495276
10559410
10774725
10843805
11042159
11076861
11114734
11217851
11222144
11403717
11439183
11567058
11748150
11830578
11830579
12124402
12217323
12421703
12466851
12477932
12528186
12684176
12895420
14681479
15014130
15046871
15328020
15517401
15788771
15996548
16112477
16141072
16141073
16284245
16380715
16446123
16547242
16602821
16782697
17039519
17145500
17150988
17304517
17448994
17952132
18006629
18287559
18353288
19036963
19247962
19326470
19542359
19576892
19759535
19769959
20112066
20436479
20824214
21267068
21490208
21628570
21753007
21795542
21940705
22065784
22171039
22304922
23242526
24117969

Gene Ontology  (GO ID)

Biological Process

GO:0007411  axon guidance
GO:0019933  cAMP-mediated signaling
GO:0048013  ephrin receptor signaling pathway
GO:0021766  hippocampus development
GO:0051964  negative regulation of synaptogenesis
GO:0007399  nervous system development
GO:0016310  phosphorylation
GO:0032793  positive regulation of CREB transcription factor activity
GO:0014068  positive regulation of phosphoinositide 3-kinase cascade
GO:0006468  protein amino acid phosphorylation
GO:0032956  regulation of actin cytoskeleton organization
GO:0032314  regulation of Rac GTPase activity
GO:0007169  transmembrane receptor protein tyrosine kinase signaling pathway

Cellular Component

GO:0042995  cell projection
GO:0043025  cell soma
GO:0030425  dendrite
GO:0009897  external side of plasma membrane
GO:0016021  integral to membrane
GO:0016020  membrane
GO:0048471  perinuclear region of cytoplasm
GO:0005886  plasma membrane
GO:0005791  rough endoplasmic reticulum

Molecular Function

GO:0005524  ATP binding
GO:0005003  ephrin receptor activity
GO:0005004  GPI-linked ephrin receptor activity
GO:0070851  growth factor receptor binding
GO:0016301  kinase activity
GO:0000166  nucleotide binding
GO:0005515  protein binding
GO:0004672  protein kinase activity
GO:0004713  protein tyrosine kinase activity
GO:0016740  transferase activity
GO:0016772  transferase activity, transferring phosphorus-containing groups
GO:0004714  transmembrane receptor protein tyrosine kinase activity