v-erb-a erythroblastic leukemia viral oncogene homolog 4 (avian)

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Synonym

ErbB4, Mer4, Erbb4, Receptor tyrosine-protein kinase erbB-4

normal 40 tissues
developmental tissues and primary cells（FANTOM5 CAGE）

Choropleth map on BodyParts3D

Choropleth maps on 3D human body images were generated by the relative gene expression values measured by GeneChip.

Classification in 40 Organs

brain

blood

connective

EST

cerebrum:12.20

cerebellum:-

brain stem:-

corpus callosum/glia:-

pineal gland:-

peripheral nerve:-

spine:-

retina:-

eye:-

artery/aorta:-

vein:-

lymphnode:-

peripheral blood:-

spleen:-

thymus:-

bone marrow:-

adipose:-

bone:-

skin:-

GeneChip

nodata

CAGE

cerebrum:2.89

cerebellum:-

brain stem:3.10

corpus callosum/glia:-

pineal gland:-

peripheral nerve:-

spine:3.15

retina:-

eye:-

artery/aorta:2.11

vein:-

lymphnode:0

peripheral blood:-

spleen:0.16

thymus:0

bone marrow:-

adipose:-

bone:0

skin:0.29

RNA-seq

nodata

reproductive

muscular

alimentary

liver

lung

urinary

endo/exo-crine

EST

uterus:-

placenta:-

prostate:-

ovary:-

testis:-

heart:-

muscle:-

esophagus:-

stomach:-

intestine:-

colon:-

liver/hepato:-

lung:-

bladder:-

kidney:16.10

pituitary:-

thyroid/parathyroid:-

adrenal gland:-

pancreas:-

breast:-

salivary:-

GeneChip

nodata

CAGE

uterus:0.97

placenta:0

prostate:0.74

ovary:0.45

testis:0.45

heart:-

muscle:-

esophagus:-

stomach:0

intestine:0

colon:0

liver/hepato:1.52

lung:0.17

bladder:0.68

kidney:-

pituitary:1.81

thyroid/parathyroid:-

adrenal gland:0.14

pancreas:1.30

breast:1.89

salivary:-

RNA-seq

nodata

IDs

Refseq ID	XM_001002143
Gene ID	13869
Unigene ID	Mm.442420
Probe set ID	-
Ensembl ID	-

Orthologous Gene

Human [0]
Rat [0]

Chromosomal Region

1C3 [68,078,760 - 69,154,633]

Search genes near this gene
- Between -5kb and +5kb
- Between -10kb and +10kb

Gene Family (Interpro ID)

IPR000719	Protein kinase, catalytic domain
IPR011009	Protein kinase-like domain
IPR002290	Serine/threonine-protein kinase domain
IPR017442	Serine/threonine-protein kinase-like domain
IPR016245	Tyrosine protein kinase, EGF/ERB/XmrK receptor
IPR020685	Tyrosine-protein kinase
IPR001245	Tyrosine-protein kinase, catalytic domain
IPR020933	Tyrosine-protein kinase, fibroblast growth factor receptor, conserved region
IPR020635	Tyrosine-protein kinase, subgroup, catalytic domain

Gene Ontology (GO ID)

Biological Process

GO:0006915	apoptosis
GO:0045165	cell fate commitment
GO:0016477	cell migration
GO:0021551	central nervous system morphogenesis
GO:0009880	embryonic pattern specification
GO:0007507	heart development
GO:0007595	lactation
GO:0060749	mammary gland alveolus development
GO:0060644	mammary gland epithelial cell differentiation
GO:0043653	mitochondrial fragmentation during apoptosis
GO:0007275	multicellular organismal development
GO:0043066	negative regulation of apoptosis
GO:0008285	negative regulation of cell proliferation
GO:0010656	negative regulation of muscle cell apoptosis
GO:0007399	nervous system development
GO:0001755	neural crest cell migration
GO:0021889	olfactory bulb interneuron differentiation
GO:0018108	peptidyl-tyrosine phosphorylation
GO:0016310	phosphorylation
GO:0060045	positive regulation of cardiac muscle cell proliferation
GO:0030335	positive regulation of cell migration
GO:0008284	positive regulation of cell proliferation
GO:0050679	positive regulation of epithelial cell proliferation
GO:0070374	positive regulation of ERK1 and ERK2 cascade
GO:0046326	positive regulation of glucose import
GO:0032230	positive regulation of synaptic transmission, GABAergic
GO:0045893	positive regulation of transcription, DNA-dependent
GO:0042523	positive regulation of tyrosine phosphorylation of Stat5 protein
GO:0046777	protein amino acid autophosphorylation
GO:0006468	protein amino acid phosphorylation
GO:0030334	regulation of cell migration
GO:0006355	regulation of transcription, DNA-dependent
GO:0007165	signal transduction
GO:0043129	surfactant homeostasis
GO:0060074	synapse maturation
GO:0006351	transcription, DNA-dependent
GO:0007169	transmembrane receptor protein tyrosine kinase signaling pathway

Cellular Component

GO:0016323	basolateral plasma membrane
GO:0005901	caveola
GO:0005737	cytoplasm
GO:0016021	integral to membrane
GO:0016020	membrane
GO:0045121	membrane raft
GO:0005739	mitochondrion
GO:0005634	nucleus
GO:0005886	plasma membrane
GO:0014069	postsynaptic density

Molecular Function

GO:0005524	ATP binding
GO:0044212	DNA regulatory region binding
GO:0005154	epidermal growth factor receptor binding
GO:0016301	kinase activity
GO:0000166	nucleotide binding
GO:0005515	protein binding
GO:0042803	protein homodimerization activity
GO:0004672	protein kinase activity
GO:0004713	protein tyrosine kinase activity
GO:0004716	receptor signaling protein tyrosine kinase activity
GO:0016740	transferase activity
GO:0016772	transferase activity, transferring phosphorus-containing groups
GO:0004714	transmembrane receptor protein tyrosine kinase activity

v-erb-a erythroblastic leukemia viral oncogene homolog 4 (avian)

Synonym

Expression Pattern

Choropleth map on BodyParts3D

Classification in 40 Organs

Gene Information

IDs

Orthologous Gene

Chromosomal Region

Gene Family (Interpro ID)

Link to Pubmed (Pubmed ID)

Gene Ontology (GO ID)

Biological Process

Cellular Component

Molecular Function