fibroblast growth factor 1

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Synonym

Fgf-1, aFGF, fibroblast growth factor 1, Acidic fibroblast growth factor, Fgfa, HBGF-1, Heparin-binding growth factor 1 precursor, Fgf1, fibroblast growth factor 1 (acidic)

Choropleth map on BodyParts3D

Choropleth maps on 3D human body images were generated by the relative gene expression values measured by GeneChip.

Classification in 40 Organs

brain blood connective
EST cerebrum:19.10 cerebellum:55.30 brain stem:254.20 corpus callosum/glia:- pineal gland:257.80 peripheral nerve:305.70 spine:189.10 retina:- eye:30.40 artery/aorta:84.40 vein:- lymphnode:- peripheral blood:- spleen:13.20 thymus:59.30 bone marrow:- adipose:- bone:12.50 skin:7.90
GeneChip cerebrum:8.17 cerebellum:9.38 brain stem:- corpus callosum/glia:- pineal gland:- peripheral nerve:11.82 spine:10.65 retina:8.40 eye:8.27 artery/aorta:- vein:5.41 lymphnode:5.88 peripheral blood:- spleen:7.33 thymus:- bone marrow:5.33 adipose:7.73 bone:6.28 skin:6.82
CAGE cerebrum:4.31 cerebellum:- brain stem:5.17 corpus callosum/glia:- pineal gland:- peripheral nerve:- spine:5.71 retina:- eye:- artery/aorta:3.58 vein:- lymphnode:2.58 peripheral blood:- spleen:2.71 thymus:2.03 bone marrow:- adipose:- bone:1.69 skin:2.88
RNA-seq cerebrum:8.63 cerebellum:- brain stem:- corpus callosum/glia:- pineal gland:- peripheral nerve:- spine:- retina:- eye:- artery/aorta:- vein:- lymphnode:- peripheral blood:- spleen:- thymus:- bone marrow:- adipose:- bone:- skin:-
reproductive muscular alimentary liver lung urinary endo/exo-crine
EST uterus:- placenta:13.80 prostate:61.80 ovary:23 testis:- heart:93 muscle:71 esophagus:- stomach:65.50 intestine:- colon:35.20     liver/hepato:63.40        lung:60.30    bladder:330.90 kidney:120.90 pituitary:25.80 thyroid/parathyroid:- adrenal gland:- pancreas:- breast:9.80 salivary:-
GeneChip uterus:6.43 placenta:5.79 prostate:9.78 ovary:8.56 testis:4.79 heart:10.30 muscle:7.31 esophagus:- stomach:6.33 intestine:6.87 colon:- liver/hepato:9.25 lung:10.45 bladder:7.80 kidney:10.57 pituitary:7.37 thyroid/parathyroid:- adrenal gland:7.58 pancreas:6.04 breast:7.62 salivary:8.13
CAGE uterus:2.28 placenta:1.07 prostate:4.20 ovary:2.74 testis:0.45 heart:- muscle:- esophagus:- stomach:2.26 intestine:2.58 colon:2.24     liver/hepato:4.94    lung:5.29 bladder:3.12 kidney:- pituitary:3.49 thyroid/parathyroid:- adrenal gland:3.50 pancreas:2.45 breast:3.17 salivary:-
RNA-seq uterus:- placenta:- prostate:- ovary:- testis:- heart:- muscle:1.46 esophagus:- stomach:- intestine:- colon:-     liver/hepato:6.90        lung:-    bladder:- kidney:- pituitary:- thyroid/parathyroid:- adrenal gland:- pancreas:- breast:- salivary:-

IDs

Refseq ID NM_010197
Gene ID 14164
Unigene ID Mm.241282
Probe set ID 1423136_at  [Mouse430_2]
Ensembl ID ENSMUSG00000036585

Orthologous Gene

Human[12]  NM_000800, NM_001144892, NM_001144934, NM_001144935, NM_033136, NM_033137
Rat [0]  

Chromosomal Region

-

Gene Family (Interpro ID)

Link to Pubmed  (Pubmed ID)

Gene Ontology  (GO ID)

Biological Process

GO:0001525  angiogenesis
GO:0060681  branch elongation involved in ureteric bud branching
GO:0060038  cardiac muscle cell proliferation
GO:0030154  cell differentiation
GO:0034605  cellular response to heat
GO:0008543  fibroblast growth factor receptor signaling pathway
GO:0001759  induction of an organ
GO:0030324  lung development
GO:0007275  multicellular organismal development
GO:0045766  positive regulation of angiogenesis
GO:0051781  positive regulation of cell division
GO:0030335  positive regulation of cell migration
GO:0008284  positive regulation of cell proliferation
GO:0045542  positive regulation of cholesterol biosynthetic process
GO:0050679  positive regulation of epithelial cell proliferation
GO:0001934  positive regulation of protein amino acid phosphorylation
GO:0010740  positive regulation of protein kinase cascade
GO:0045944  positive regulation of transcription from RNA polymerase II promoter
GO:0045893  positive regulation of transcription, DNA-dependent
GO:0060979  vasculogenesis involved in coronary vascular morphogenesis

Cellular Component

GO:0005737  cytoplasm
GO:0005829  cytosol
GO:0005576  extracellular region
GO:0005615  extracellular space
GO:0005730  nucleolus
GO:0005634  nucleus
GO:0005578  proteinaceous extracellular matrix

Molecular Function

GO:0005104  fibroblast growth factor receptor binding
GO:0008083  growth factor activity
GO:0008201  heparin binding
GO:0030544  Hsp70 protein binding
GO:0005515  protein binding