follicle stimulating hormone receptor

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Synonym

Fshr, Follitropin receptor, follicle-stimulating hormone receptor, Follicle-stimulating hormone receptor precursor, FSH-R, follicle stimulating hormone receptor

Expression Pattern

Choropleth map on BodyParts3D

Choropleth maps on 3D human body images were generated by the relative gene expression values measured by GeneChip.

Classification in 40 Organs

brain blood connective
EST cerebrum:- cerebellum:- brain stem:- corpus callosum/glia:- pineal gland:- peripheral nerve:- spine:- retina:- eye:- artery/aorta:- vein:- lymphnode:- peripheral blood:- spleen:- thymus:- bone marrow:- adipose:- bone:- skin:-
GeneChip cerebrum:4.97 cerebellum:5.19 brain stem:- corpus callosum/glia:- pineal gland:- peripheral nerve:4.92 spine:5.18 retina:5.24 eye:5.46 artery/aorta:- vein:5.07 lymphnode:4.67 peripheral blood:- spleen:4.98 thymus:- bone marrow:4.76 adipose:4.97 bone:4.89 skin:5.02
CAGE cerebrum:0 cerebellum:- brain stem:0 corpus callosum/glia:- pineal gland:- peripheral nerve:- spine:0 retina:- eye:- artery/aorta:0 vein:- lymphnode:0 peripheral blood:- spleen:0 thymus:0 bone marrow:- adipose:- bone:0 skin:0
RNA-seq nodata
reproductive muscular alimentary liver lung urinary endo/exo-crine
EST uterus:- placenta:- prostate:- ovary:- testis:14.80 heart:- muscle:- esophagus:- stomach:- intestine:- colon:-     liver/hepato:-        lung:-    bladder:- kidney:- pituitary:- thyroid/parathyroid:- adrenal gland:- pancreas:- breast:- salivary:-
GeneChip uterus:4.91 placenta:4.96 prostate:4.89 ovary:6.21 testis:5.68 heart:5.54 muscle:5.28 esophagus:- stomach:5 intestine:4.98 colon:- liver/hepato:5.25 lung:4.95 bladder:4.92 kidney:5.21 pituitary:4.95 thyroid/parathyroid:- adrenal gland:4.94 pancreas:4.96 breast:4.98 salivary:5.43
CAGE uterus:0 placenta:0 prostate:0 ovary:2.82 testis:0.99 heart:- muscle:- esophagus:- stomach:0 intestine:0 colon:0     liver/hepato:0    lung:0 bladder:0 kidney:- pituitary:0 thyroid/parathyroid:- adrenal gland:0 pancreas:0 breast:0 salivary:-
RNA-seq nodata

Gene Information

IDs

Refseq ID NM_013523
Gene ID 14309
Unigene ID Mm.57155
Probe set ID 1450810_at  [Mouse430_2]
Ensembl ID ENSMUSG00000032937

Orthologous Gene

Human[2]  NM_000145, NM_181446
Rat [0]  

Chromosomal Region

-

Gene Family (Interpro ID)

IPR000276  7TM GPCR, rhodopsin-like
IPR002272  Follicle-stimulating hormone receptor
IPR002131  Glycoprotein hormone receptor
IPR017452  GPCR, rhodopsin-like superfamily

Link to Pubmed  (Pubmed ID)

1459341
8185825
8855829
9020850
9100567
9206032
9282997
9397953
9811848
10330114
10349636
10773385
10775161
10803590
10915803
10944452
11042159
11076861
11089565
11145601
11217851
11226072
11279525
11459817
11466221
12135868
12135869
12193578
12204217
12403847
12466851
12477932
12488339
12578530
12801992
12801993
14502087
14551232
14552897
14680821
14998910
15232063
15659488
15973687
16024815
16034175
16141072
16141073
16344272
16352410
16416028
16602821
16630814
16672355
16919269
17069759
17081682
17234334
17332067
17470386
17657853
17681281
18063689
18287559
18403489
18566134
18599597
18676690
18753614
20172968
20615452
21267068
21339736
21688198
22510272
22514715
22908268
23086931
23300903

Gene Ontology  (GO ID)

Biological Process

GO:0007189  activation of adenylate cyclase activity by G-protein signaling pathway
GO:0007200  activation of phospholipase C activity by G-protein coupled receptor protein signaling pathway coupled to IP3 second messenger
GO:0009992  cellular water homeostasis
GO:0042699  follicle-stimulating hormone signaling pathway
GO:0007186  G-protein coupled receptor protein signaling pathway
GO:0007188  G-protein signaling, coupled to cAMP nucleotide second messenger
GO:0007193  inhibition of adenylate cyclase activity by G-protein signaling pathway
GO:0007626  locomotory behavior
GO:0045779  negative regulation of bone resorption
GO:0031175  neuron projection development
GO:0001541  ovarian follicle development
GO:0022602  ovulation cycle process
GO:0033148  positive regulation of estrogen receptor signaling pathway
GO:0001545  primary ovarian follicle growth
GO:0060408  regulation of acetylcholine metabolic process
GO:0033044  regulation of chromosome organization
GO:0033146  regulation of estrogen receptor signaling pathway
GO:0032350  regulation of hormone metabolic process
GO:0043408  regulation of MAPKKK cascade
GO:0045670  regulation of osteoclast differentiation
GO:0010640  regulation of platelet-derived growth factor receptor signaling pathway
GO:0001932  regulation of protein amino acid phosphorylation
GO:0003073  regulation of systemic arterial blood pressure
GO:0060009  Sertoli cell development
GO:0060011  Sertoli cell proliferation
GO:0007165  signal transduction
GO:0035092  sperm chromatin condensation
GO:0007286  spermatid development
GO:0007283  spermatogenesis
GO:0035093  spermatogenesis, exchange of chromosomal proteins
GO:0045056  transcytosis
GO:0060065  uterus development

Cellular Component

GO:0009986  cell surface
GO:0005768  endosome
GO:0016021  integral to membrane
GO:0016020  membrane
GO:0005886  plasma membrane

Molecular Function

GO:0004963  follicle-stimulating hormone receptor activity
GO:0004930  G-protein coupled receptor activity
GO:0017046  peptide hormone binding
GO:0016500  protein-hormone receptor activity
GO:0004871  signal transducer activity