growth factor receptor bound protein 2

Synonym

SH2/SH3 adapter GRB2, Growth factor receptor-bound protein 2, AA408164, Adapter protein GRB2, Grb2, Ash, growth factor receptor bound protein 2

normal 40 tissues
developmental tissues and primary cells（FANTOM5 CAGE）

Choropleth map on BodyParts3D

Choropleth maps on 3D human body images were generated by the relative gene expression values measured by GeneChip.

Classification in 40 Organs

brain

blood

connective

EST

cerebrum:159.80

cerebellum:128.90

brain stem:63.60

corpus callosum/glia:-

pineal gland:257.80

peripheral nerve:133.80

spine:189.10

retina:-

eye:68.40

artery/aorta:-

vein:-

lymphnode:507.70

peripheral blood:-

spleen:210.70

thymus:118.60

bone marrow:525.70

adipose:-

bone:150.30

skin:47.50

GeneChip

cerebrum:8.74

cerebellum:8.79

brain stem:-

corpus callosum/glia:-

pineal gland:-

peripheral nerve:8.91

spine:8.39

retina:7.56

eye:7.86

artery/aorta:-

vein:8.35

lymphnode:10.23

peripheral blood:-

spleen:10.24

thymus:-

bone marrow:9.51

adipose:8.24

bone:9.09

skin:7.55

CAGE

cerebrum:4.69

cerebellum:-

brain stem:4.60

corpus callosum/glia:-

pineal gland:-

peripheral nerve:-

spine:4.69

retina:-

eye:-

artery/aorta:4.01

vein:-

lymphnode:5.10

peripheral blood:-

spleen:4.96

thymus:4.68

bone marrow:-

adipose:-

bone:4.84

skin:4.13

RNA-seq

cerebrum:29.59

cerebellum:-

brain stem:-

corpus callosum/glia:-

pineal gland:-

peripheral nerve:-

spine:-

retina:-

eye:-

artery/aorta:-

vein:-

lymphnode:-

peripheral blood:-

spleen:-

thymus:-

bone marrow:-

adipose:-

bone:-

skin:-

reproductive

muscular

alimentary

liver

lung

urinary

endo/exo-crine

EST

uterus:43.60

placenta:110.50

prostate:-

ovary:23

testis:7.40

heart:93

muscle:-

esophagus:-

stomach:32.70

intestine:258.80

colon:52.90

liver/hepato:54.30

lung:150.60

bladder:-

kidney:48.40

pituitary:193.80

thyroid/parathyroid:112.50

adrenal gland:-

pancreas:56.30

breast:133.90

salivary:54

GeneChip

uterus:8.34

placenta:9.57

prostate:7.84

ovary:8.21

testis:6.46

heart:8.97

muscle:8.19

esophagus:-

stomach:8.46

intestine:8.67

colon:-

liver/hepato:8.45

lung:8.36

bladder:8.09

kidney:7.84

pituitary:8.05

thyroid/parathyroid:-

adrenal gland:8.27

pancreas:7.64

breast:8.36

salivary:7.71

CAGE

uterus:4.32

placenta:4.91

prostate:3.91

ovary:4.12

testis:3.03

heart:-

muscle:-

esophagus:-

stomach:4.10

intestine:4.42

colon:4.52

liver/hepato:4.23

lung:4.53

bladder:4.17

kidney:-

pituitary:4.39

thyroid/parathyroid:-

adrenal gland:4.63

pancreas:4.21

breast:4.17

salivary:-

RNA-seq

uterus:-

placenta:-

prostate:-

ovary:-

testis:-

heart:-

muscle:9.87

esophagus:-

stomach:-

intestine:-

colon:-

liver/hepato:7.07

lung:-

bladder:-

kidney:-

pituitary:-

thyroid/parathyroid:-

adrenal gland:-

pancreas:-

breast:-

salivary:-

IDs

Refseq ID	NM_008163
Gene ID	14784
Unigene ID	Mm.439649
Probe set ID	1449111_a_at [Mouse430_2]
Ensembl ID	ENSMUSG00000059923

Orthologous Gene

Human[4]	NM_002086, NM_203506
Rat [0]

Chromosomal Region

Gene Family (Interpro ID)

Gene Ontology (GO ID)

Biological Process

GO:0007568	aging
GO:0048646	anatomical structure formation involved in morphogenesis
GO:0060670	branching involved in embryonic placenta morphogenesis
GO:0030154	cell differentiation
GO:0071479	cellular response to ionizing radiation
GO:0042770	DNA damage response, signal transduction
GO:0008543	fibroblast growth factor receptor signaling pathway
GO:0008286	insulin receptor signaling pathway
GO:0030838	positive regulation of actin filament polymerization
GO:0051291	protein heterooligomerization
GO:0007265	Ras protein signal transduction
GO:0031623	receptor internalization
GO:0043408	regulation of MAPKKK cascade

Cellular Component

GO:0005737	cytoplasm
GO:0005768	endosome
GO:0005794	Golgi apparatus
GO:0070436	Grb2-EGFR complex
GO:0016020	membrane
GO:0005634	nucleus
GO:0005886	plasma membrane
GO:0043234	protein complex
GO:0008180	signalosome
GO:0012506	vesicle membrane

Molecular Function

GO:0046875	ephrin receptor binding
GO:0005154	epidermal growth factor receptor binding
GO:0042802	identical protein binding
GO:0043560	insulin receptor substrate binding
GO:0005168	neurotrophin TRKA receptor binding
GO:0051219	phosphoprotein binding
GO:0001784	phosphotyrosine binding
GO:0005515	protein binding
GO:0019904	protein domain specific binding
GO:0019901	protein kinase binding
GO:0019903	protein phosphatase binding
GO:0017124	SH3 domain binding
GO:0005070	SH3/SH2 adaptor activity

growth factor receptor bound protein 2

Synonym

Expression Pattern

Choropleth map on BodyParts3D

Classification in 40 Organs

Gene Information

IDs

Orthologous Gene

Chromosomal Region

Gene Family (Interpro ID)

Link to Pubmed (Pubmed ID)

Gene Ontology (GO ID)

Biological Process

Cellular Component

Molecular Function