histone deacetylase 3

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Synonym

histone deacetylase 3, HD3, AW537363, Hdac3, Histone deacetylase 3

normal 40 tissues
developmental tissues and primary cells（FANTOM5 CAGE）

Choropleth map on BodyParts3D

Choropleth maps on 3D human body images were generated by the relative gene expression values measured by GeneChip.

Classification in 40 Organs

brain

blood

connective

EST

cerebrum:60.80

cerebellum:147.40

brain stem:-

corpus callosum/glia:-

pineal gland:-

peripheral nerve:95.50

spine:141.90

retina:160.70

eye:76

artery/aorta:-

vein:-

lymphnode:10.80

peripheral blood:-

spleen:39.50

thymus:29.60

bone marrow:64.10

adipose:-

bone:150.30

skin:79.20

GeneChip

cerebrum:9.33

cerebellum:8.77

brain stem:-

corpus callosum/glia:-

pineal gland:-

peripheral nerve:8.90

spine:9.39

retina:8.25

eye:8.27

artery/aorta:-

vein:9.38

lymphnode:9.06

peripheral blood:-

spleen:8.76

thymus:-

bone marrow:9.01

adipose:9.35

bone:9.01

skin:9.21

CAGE

cerebrum:3.57

cerebellum:-

brain stem:3.61

corpus callosum/glia:-

pineal gland:-

peripheral nerve:-

spine:3.69

retina:-

eye:-

artery/aorta:3.17

vein:-

lymphnode:3.10

peripheral blood:-

spleen:2.69

thymus:3.10

bone marrow:-

adipose:-

bone:3.10

skin:2.99

RNA-seq

cerebrum:13.38

cerebellum:-

brain stem:-

corpus callosum/glia:-

pineal gland:-

peripheral nerve:-

spine:-

retina:-

eye:-

artery/aorta:-

vein:-

lymphnode:-

peripheral blood:-

spleen:-

thymus:-

bone marrow:-

adipose:-

bone:-

skin:-

reproductive

muscular

alimentary

liver

lung

urinary

endo/exo-crine

EST

uterus:-

placenta:82.80

prostate:92.60

ovary:11.50

testis:14.80

heart:-

muscle:35.50

esophagus:-

stomach:-

intestine:-

colon:35.20

liver/hepato:36.20

lung:160.70

bladder:-

kidney:32.20

pituitary:116.30

thyroid/parathyroid:-

adrenal gland:-

pancreas:37.50

breast:166.50

salivary:108

GeneChip

uterus:9.61

placenta:9.13

prostate:9.31

ovary:9.47

testis:9

heart:8.86

muscle:9.57

esophagus:-

stomach:9.22

intestine:9.11

colon:-

liver/hepato:8.57

lung:8.49

bladder:9.13

kidney:8.69

pituitary:9.26

thyroid/parathyroid:-

adrenal gland:9.67

pancreas:7.80

breast:9.88

salivary:9.58

CAGE

uterus:3.54

placenta:3.21

prostate:3.42

ovary:3.51

testis:4.20

heart:-

muscle:-

esophagus:-

stomach:3.57

intestine:3.67

colon:3.36

liver/hepato:3.30

lung:3.02

bladder:3.56

kidney:-

pituitary:3.47

thyroid/parathyroid:-

adrenal gland:3.41

pancreas:2.56

breast:3.95

salivary:-

RNA-seq

uterus:-

placenta:-

prostate:-

ovary:-

testis:-

heart:-

muscle:11.40

esophagus:-

stomach:-

intestine:-

colon:-

liver/hepato:5.27

lung:-

bladder:-

kidney:-

pituitary:-

thyroid/parathyroid:-

adrenal gland:-

pancreas:-

breast:-

salivary:-

IDs

Refseq ID	NM_010411
Gene ID	15183
Unigene ID	Mm.20521
Probe set ID	1426437_s_at [Mouse430_2]
Ensembl ID	ENSMUSG00000024454

Orthologous Gene

Human[1]	NM_003883
Rat[1]	NM_053448

Chromosomal Region

Gene Family (Interpro ID)

IPR003084	Histone deacetylase
IPR000286	Histone deacetylase superfamily

Gene Ontology (GO ID)

Biological Process

GO:0016568	chromatin modification
GO:0032922	circadian regulation of gene expression
GO:0016575	histone deacetylation
GO:0070932	histone H3 deacetylation
GO:0070933	histone H4 deacetylation
GO:0046329	negative regulation of JNK cascade
GO:0000122	negative regulation of transcription from RNA polymerase II promoter
GO:0045892	negative regulation of transcription, DNA-dependent
GO:0006476	protein amino acid deacetylation
GO:0007346	regulation of mitotic cell cycle
GO:0040014	regulation of multicellular organism growth
GO:0006355	regulation of transcription, DNA-dependent
GO:0051225	spindle assembly
GO:0006351	transcription, DNA-dependent

Cellular Component

GO:0000785	chromatin
GO:0005737	cytoplasm
GO:0000118	histone deacetylase complex
GO:0005634	nucleus
GO:0005876	spindle microtubule
GO:0017053	transcriptional repressor complex

Molecular Function

GO:0003682	chromatin binding
GO:0031490	chromatin DNA binding
GO:0003677	DNA binding
GO:0019899	enzyme binding
GO:0004407	histone deacetylase activity
GO:0031078	histone deacetylase activity (H3-K14 specific)
GO:0034739	histone deacetylase activity (H3-K16 specific)
GO:0032129	histone deacetylase activity (H3-K9 specific)
GO:0042826	histone deacetylase binding
GO:0016787	hydrolase activity
GO:0032041	NAD-dependent histone deacetylase activity (H3-K14 specific)
GO:0046969	NAD-dependent histone deacetylase activity (H3-K9 specific)
GO:0046970	NAD-dependent histone deacetylase activity (H4-K16 specific)
GO:0005515	protein binding
GO:0033558	protein deacetylase activity
GO:0003714	transcription corepressor activity
GO:0008134	transcription factor binding

histone deacetylase 3

Synonym

Expression Pattern

Choropleth map on BodyParts3D

Classification in 40 Organs

Gene Information

IDs

Orthologous Gene

Chromosomal Region

Gene Family (Interpro ID)

Link to Pubmed (Pubmed ID)

Gene Ontology (GO ID)

Biological Process

Cellular Component

Molecular Function