hepatocyte growth factor

Synonym

Hgf, hepatocyte growth factor, HGF/SF, Scatter factor, scatter factor, NK1, Hepatocyte growth factor precursor, C230052L06Rik, NK2, SF/HGF, SF, Hepatopoeitin A

normal 40 tissues
developmental tissues and primary cells（FANTOM5 CAGE）

Choropleth map on BodyParts3D

Choropleth maps on 3D human body images were generated by the relative gene expression values measured by GeneChip.

Classification in 40 Organs

brain

blood

connective

EST

cerebrum:-

cerebellum:36.80

brain stem:-

corpus callosum/glia:-

pineal gland:-

peripheral nerve:-

spine:-

retina:-

eye:-

artery/aorta:-

vein:-

lymphnode:-

peripheral blood:-

spleen:-

thymus:19.80

bone marrow:-

adipose:-

bone:-

skin:7.90

GeneChip

cerebrum:4.93

cerebellum:4.82

brain stem:-

corpus callosum/glia:-

pineal gland:-

peripheral nerve:5.08

spine:4.72

retina:4.52

eye:4.88

artery/aorta:-

vein:4.90

lymphnode:5.05

peripheral blood:-

spleen:4.88

thymus:-

bone marrow:5.55

adipose:4.97

bone:5.22

skin:4.97

CAGE

cerebrum:0.99

cerebellum:-

brain stem:0.65

corpus callosum/glia:-

pineal gland:-

peripheral nerve:-

spine:1.05

retina:-

eye:-

artery/aorta:1.11

vein:-

lymphnode:2.65

peripheral blood:-

spleen:1.78

thymus:1.26

bone marrow:-

adipose:-

bone:1.84

skin:1.15

RNA-seq

cerebrum:0.67

cerebellum:-

brain stem:-

corpus callosum/glia:-

pineal gland:-

peripheral nerve:-

spine:-

retina:-

eye:-

artery/aorta:-

vein:-

lymphnode:-

peripheral blood:-

spleen:-

thymus:-

bone marrow:-

adipose:-

bone:-

skin:-

reproductive

muscular

alimentary

liver

lung

urinary

endo/exo-crine

EST

uterus:-

placenta:-

prostate:-

ovary:11.50

testis:29.60

heart:74.40

muscle:71

esophagus:-

stomach:-

intestine:-

colon:-

liver/hepato:9.10

lung:10

bladder:-

kidney:-

pituitary:-

thyroid/parathyroid:-

adrenal gland:-

pancreas:-

breast:-

salivary:-

GeneChip

uterus:5.02

placenta:4.71

prostate:4.71

ovary:4.69

testis:5.03

heart:4.98

muscle:4.86

esophagus:-

stomach:4.80

intestine:4.99

colon:-

liver/hepato:5.95

lung:5.98

bladder:5.11

kidney:4.82

pituitary:4.94

thyroid/parathyroid:-

adrenal gland:4.63

pancreas:4.83

breast:5.10

salivary:5.40

CAGE

uterus:2.64

placenta:1.30

prostate:1.84

ovary:2.11

testis:0.45

heart:-

muscle:-

esophagus:-

stomach:2.04

intestine:1.22

colon:1.68

liver/hepato:3.93

lung:3.67

bladder:2.59

kidney:-

pituitary:1.31

thyroid/parathyroid:-

adrenal gland:1.87

pancreas:0.84

breast:1.73

salivary:-

RNA-seq

uterus:-

placenta:-

prostate:-

ovary:-

testis:-

heart:-

muscle:-

esophagus:-

stomach:-

intestine:-

colon:-

liver/hepato:2.35

lung:-

bladder:-

kidney:-

pituitary:-

thyroid/parathyroid:-

adrenal gland:-

pancreas:-

breast:-

salivary:-

IDs

Refseq ID	NM_010427
Gene ID	15234
Unigene ID	Mm.267078
Probe set ID	1425379_at [Mouse430_2]
Ensembl ID	ENSMUSG00000028864

Orthologous Gene

Human[11]	NM_000601, NM_001010931, NM_001010932, NM_001010933, NM_001010934
Rat [0]

Chromosomal Region

Gene Family (Interpro ID)

IPR003609	Apple-like
IPR000001	Kringle
IPR013806	Kringle-like fold
IPR001254	Peptidase S1/S6, chymotrypsin/Hap
IPR001314	Peptidase S1A, chymotrypsin
IPR009003	Serine/cysteine peptidase, trypsin-like

Gene Ontology (GO ID)

Biological Process

GO:0000187	activation of MAPK activity
GO:0060326	cell chemotaxis
GO:0000902	cell morphogenesis
GO:0008283	cell proliferation
GO:0048012	hepatocyte growth factor receptor signaling pathway
GO:0001889	liver development
GO:0051450	myoblast proliferation
GO:0043066	negative regulation of apoptosis
GO:0043154	negative regulation of caspase activity
GO:0090201	negative regulation of release of cytochrome c from mitochondria
GO:0050918	positive chemotaxis
GO:0030335	positive regulation of cell migration
GO:0050731	positive regulation of peptidyl-tyrosine phosphorylation
GO:0014068	positive regulation of phosphoinositide 3-kinase cascade
GO:0006508	proteolysis
GO:0060665	regulation of branching involved in salivary gland morphogenesis by mesenchymal-epithelial signaling

Cellular Component

GO:0005615

extracellular space

Molecular Function

GO:0003824	catalytic activity
GO:0042056	chemoattractant activity
GO:0008083	growth factor activity
GO:0042802	identical protein binding
GO:0046982	protein heterodimerization activity
GO:0004252	serine-type endopeptidase activity

hepatocyte growth factor

Synonym

Expression Pattern

Choropleth map on BodyParts3D

Classification in 40 Organs

Gene Information

IDs

Orthologous Gene

Chromosomal Region

Gene Family (Interpro ID)

Link to Pubmed (Pubmed ID)

Gene Ontology (GO ID)

Biological Process

Cellular Component

Molecular Function