hydroxysteroid 11-beta dehydrogenase 2

Synonym

11-beta-hydroxysteroid dehydrogenase type 2, Corticosteroid 11-beta-dehydrogenase isozyme 2, 11(beta)-HSD2, Hsd11k, Hsd11b2, 11-DH2, NAD-dependent 11-beta-hydroxysteroid dehydrogenase, 11-beta-HSD2, hydroxysteroid 11-beta dehydrogenase 2

normal 40 tissues
developmental tissues and primary cells（FANTOM5 CAGE）

Choropleth map on BodyParts3D

Choropleth maps on 3D human body images were generated by the relative gene expression values measured by GeneChip.

Classification in 40 Organs

brain

blood

connective

EST

cerebrum:12.20

cerebellum:184.20

brain stem:31.80

corpus callosum/glia:-

pineal gland:-

peripheral nerve:-

spine:236.40

retina:-

eye:7.60

artery/aorta:-

vein:-

lymphnode:-

peripheral blood:43.10

spleen:-

thymus:9.90

bone marrow:-

adipose:-

bone:12.50

skin:-

GeneChip

cerebrum:3.99

cerebellum:4.23

brain stem:-

corpus callosum/glia:-

pineal gland:-

peripheral nerve:3.81

spine:4.10

retina:3.91

eye:4.28

artery/aorta:-

vein:4.19

lymphnode:3.88

peripheral blood:-

spleen:4.01

thymus:-

bone marrow:3.96

adipose:4.17

bone:4.03

skin:3.96

CAGE

cerebrum:0

cerebellum:-

brain stem:0.14

corpus callosum/glia:-

pineal gland:-

peripheral nerve:-

spine:0

retina:-

eye:-

artery/aorta:0

vein:-

lymphnode:0.42

peripheral blood:-

spleen:0.41

thymus:0.27

bone marrow:-

adipose:-

bone:0

skin:0.51

RNA-seq

nodata

reproductive

muscular

alimentary

liver

lung

urinary

endo/exo-crine

EST

uterus:-

placenta:41.40

prostate:-

ovary:46

testis:51.70

heart:-

muscle:-

esophagus:-

stomach:-

intestine:-

colon:370.10

liver/hepato:-

lung:-

bladder:-

kidney:48.40

pituitary:-

thyroid/parathyroid:-

adrenal gland:-

pancreas:18.80

breast:3.30

salivary:-

GeneChip

uterus:9.75

placenta:4.42

prostate:4.20

ovary:6.89

testis:4.14

heart:4.40

muscle:5.08

esophagus:-

stomach:7.96

intestine:8.06

colon:-

liver/hepato:4.21

lung:4.56

bladder:4.04

kidney:9.68

pituitary:3.96

thyroid/parathyroid:-

adrenal gland:3.97

pancreas:3.92

breast:4.79

salivary:3.84

CAGE

uterus:5.29

placenta:2.27

prostate:0

ovary:3.68

testis:0

heart:-

muscle:-

esophagus:-

stomach:0.67

intestine:1.84

colon:1.58

liver/hepato:0

lung:0.44

bladder:0

kidney:-

pituitary:0

thyroid/parathyroid:-

adrenal gland:0.14

pancreas:0

breast:1.27

salivary:-

RNA-seq

nodata

IDs

Refseq ID	NM_008289
Gene ID	15484
Unigene ID	Mm.5079
Probe set ID	1416761_at [Mouse430_2]
Ensembl ID	ENSMUSG00000031891

Orthologous Gene

Human[1]	NM_000196
Rat [0]

Chromosomal Region

Gene Family (Interpro ID)

IPR003560	2,3-dihydro-2,3-dihydroxybenzoate dehydrogenase
IPR002347	Glucose/ribitol dehydrogenase
IPR002198	Short-chain dehydrogenase/reductase SDR

Link to Pubmed (Pubmed ID)

Gene Ontology (GO ID)

Biological Process

GO:0008211	glucocorticoid metabolic process
GO:0008152	metabolic process
GO:0055114	oxidation reduction
GO:0002017	regulation of blood volume by renal aldosterone

Cellular Component

GO:0005737	cytoplasm
GO:0005783	endoplasmic reticulum
GO:0043231	intracellular membrane-bounded organelle

Molecular Function

GO:0003845	11-beta-hydroxysteroid dehydrogenase activity
GO:0051287	NAD or NADH binding
GO:0016491	oxidoreductase activity
GO:0005496	steroid binding

hydroxysteroid 11-beta dehydrogenase 2

Synonym

Expression Pattern

Choropleth map on BodyParts3D

Classification in 40 Organs

Gene Information

IDs

Orthologous Gene

Chromosomal Region

Gene Family (Interpro ID)

Link to Pubmed (Pubmed ID)

Gene Ontology (GO ID)

Biological Process

Cellular Component

Molecular Function