interferon-induced protein with tetratricopeptide repeats 3

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Synonym

IFIT-3, Ifit3, MGC107331, IRG2, Glucocorticoid-attenuated response gene 49 protein, GARG-49, Garg49, Ifi49

Expression Pattern

Choropleth map on BodyParts3D

Choropleth maps on 3D human body images were generated by the relative gene expression values measured by GeneChip.

Classification in 40 Organs

brain blood connective
EST cerebrum:12.20 cerebellum:- brain stem:- corpus callosum/glia:- pineal gland:- peripheral nerve:- spine:- retina:- eye:15.20 artery/aorta:84.40 vein:- lymphnode:- peripheral blood:14.40 spleen:171.20 thymus:9.90 bone marrow:115.40 adipose:- bone:12.50 skin:15.80
GeneChip cerebrum:6.95 cerebellum:7.36 brain stem:- corpus callosum/glia:- pineal gland:- peripheral nerve:7.79 spine:7.36 retina:8.18 eye:8.81 artery/aorta:- vein:5.70 lymphnode:8.38 peripheral blood:- spleen:8.45 thymus:- bone marrow:7.31 adipose:7.84 bone:7.18 skin:6.63
CAGE cerebrum:1.70 cerebellum:- brain stem:2.06 corpus callosum/glia:- pineal gland:- peripheral nerve:- spine:1.59 retina:- eye:- artery/aorta:3.39 vein:- lymphnode:2.99 peripheral blood:- spleen:2.20 thymus:2.78 bone marrow:- adipose:- bone:1.84 skin:1.46
RNA-seq cerebrum:1.30 cerebellum:- brain stem:- corpus callosum/glia:- pineal gland:- peripheral nerve:- spine:- retina:- eye:- artery/aorta:- vein:- lymphnode:- peripheral blood:- spleen:- thymus:- bone marrow:- adipose:- bone:- skin:-
reproductive muscular alimentary liver lung urinary endo/exo-crine
EST uterus:- placenta:- prostate:30.90 ovary:- testis:7.40 heart:- muscle:- esophagus:- stomach:65.50 intestine:- colon:17.60     liver/hepato:9.10        lung:50.20    bladder:- kidney:16.10 pituitary:- thyroid/parathyroid:- adrenal gland:- pancreas:- breast:13.10 salivary:-
GeneChip uterus:9.50 placenta:7.95 prostate:7.43 ovary:7.11 testis:5.71 heart:7.36 muscle:7.30 esophagus:- stomach:6.57 intestine:6.82 colon:- liver/hepato:7.94 lung:8.70 bladder:7.27 kidney:8.22 pituitary:6.90 thyroid/parathyroid:- adrenal gland:8.24 pancreas:5.99 breast:8.12 salivary:7.64
CAGE uterus:3.09 placenta:2.62 prostate:1.41 ovary:1.71 testis:0.45 heart:- muscle:- esophagus:- stomach:1.91 intestine:3.57 colon:1.93     liver/hepato:2.66    lung:4.34 bladder:2.66 kidney:- pituitary:2.58 thyroid/parathyroid:- adrenal gland:2.23 pancreas:1.30 breast:2.15 salivary:-
RNA-seq uterus:- placenta:- prostate:- ovary:- testis:- heart:- muscle:1.21 esophagus:- stomach:- intestine:- colon:-     liver/hepato:1.54        lung:-    bladder:- kidney:- pituitary:- thyroid/parathyroid:- adrenal gland:- pancreas:- breast:- salivary:-

Gene Information

IDs

Refseq ID NM_010501
Gene ID 15959
Unigene ID Mm.426079
Probe set ID 1449025_at  [Mouse430_2]
Ensembl ID ENSMUSG00000062488
ENSMUSG00000074896

Orthologous Gene

Human[2]  NM_001031683, NM_001549
Rat[1]  NM_001007694, NM_001549

Chromosomal Region

-

Gene Family (Interpro ID)

IPR019734  Tetratricopeptide repeat

Link to Pubmed  (Pubmed ID)

7622488
8207206
8660659
10349636
11042159
11076861
11125038
11217851
12466851
12477932
14681479
15489334
15568025
16141072
16141073
17079283
19158679
19422823
23132945

Gene Ontology  (GO ID)

Biological Process

GO:0051607  defense response to virus
GO:0045087  innate immune response

Cellular Component

GO:0005737  cytoplasm
GO:0005739  mitochondrion

Molecular Function

GO:0042802  identical protein binding
GO:0005515  protein binding