inositol 1,4,5-triphosphate receptor 3

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Synonym

Ip3r3, Type 3 InsP3 receptor, inositol 1,4,5-triphosphate receptor 3, IP3 receptor isoform 3, Type 3 inositol 1,4,5-trisphosphate receptor, Itpr-3, InsP3R3, Inositol 1,4,5-trisphosphate receptor type 3, Itpr3

Expression Pattern

Choropleth map on BodyParts3D

Choropleth maps on 3D human body images were generated by the relative gene expression values measured by GeneChip.

Classification in 40 Organs

brain blood connective
EST cerebrum:8.70 cerebellum:- brain stem:- corpus callosum/glia:- pineal gland:- peripheral nerve:- spine:- retina:- eye:30.40 artery/aorta:- vein:- lymphnode:140.40 peripheral blood:43.10 spleen:52.70 thymus:9.90 bone marrow:64.10 adipose:- bone:- skin:47.50
GeneChip cerebrum:5.87 cerebellum:6.70 brain stem:- corpus callosum/glia:- pineal gland:- peripheral nerve:8.53 spine:7.10 retina:6.50 eye:7.46 artery/aorta:- vein:7.42 lymphnode:9.15 peripheral blood:- spleen:9.81 thymus:- bone marrow:7.12 adipose:6.88 bone:6.88 skin:10.67
CAGE cerebrum:2.25 cerebellum:- brain stem:1.60 corpus callosum/glia:- pineal gland:- peripheral nerve:- spine:2.55 retina:- eye:- artery/aorta:2.65 vein:- lymphnode:4.24 peripheral blood:- spleen:3.67 thymus:3.75 bone marrow:- adipose:- bone:2.72 skin:5.06
RNA-seq cerebrum:4.30 cerebellum:- brain stem:- corpus callosum/glia:- pineal gland:- peripheral nerve:- spine:- retina:- eye:- artery/aorta:- vein:- lymphnode:- peripheral blood:- spleen:- thymus:- bone marrow:- adipose:- bone:- skin:-
reproductive muscular alimentary liver lung urinary endo/exo-crine
EST uterus:- placenta:165.70 prostate:- ovary:- testis:88.70 heart:- muscle:35.50 esophagus:- stomach:360 intestine:110.90 colon:35.20     liver/hepato:-        lung:50.20    bladder:198.50 kidney:- pituitary:25.80 thyroid/parathyroid:- adrenal gland:- pancreas:281.50 breast:169.80 salivary:108
GeneChip uterus:8.20 placenta:6.89 prostate:8.23 ovary:7.28 testis:7.49 heart:6.52 muscle:6.50 esophagus:- stomach:9.88 intestine:9.52 colon:- liver/hepato:6.44 lung:7.76 bladder:8.21 kidney:6.42 pituitary:7.57 thyroid/parathyroid:- adrenal gland:6.54 pancreas:7.46 breast:7.40 salivary:8
CAGE uterus:3.39 placenta:3.02 prostate:3.80 ovary:2.82 testis:1.48 heart:- muscle:- esophagus:- stomach:4.13 intestine:4.32 colon:4.38     liver/hepato:1.38    lung:3.92 bladder:3.62 kidney:- pituitary:3.17 thyroid/parathyroid:- adrenal gland:2.54 pancreas:3.64 breast:3.54 salivary:-
RNA-seq uterus:- placenta:- prostate:- ovary:- testis:- heart:- muscle:1.67 esophagus:- stomach:- intestine:- colon:-     liver/hepato:1.39        lung:-    bladder:- kidney:- pituitary:- thyroid/parathyroid:- adrenal gland:- pancreas:- breast:- salivary:-

Gene Information

IDs

Refseq ID NM_080553
Gene ID 16440
Unigene ID Mm.458106
Probe set ID 1417297_at  [Mouse430_2]
Ensembl ID ENSMUSG00000042644

Orthologous Gene

Human[3]  NM_002224
Rat [0]  

Chromosomal Region

-

Gene Family (Interpro ID)

-

Link to Pubmed  (Pubmed ID)

1374893
3996911
8063813
8081710
8663526
9013981
9065779
9808793
9858485
10349636
11042159
11076861
11149946
11217851
11696558
11860456
11934702
12421829
12466851
12477932
12606813
12904583
14610273
15489334
15632133
15713744
15747579
15890645
16014380
16141072
16141073
16195467
16352659
16840702
16844763
17327232
17374359
17379641
17416589
17581770
17890015
17925404
18194433
18241669
18417102
18547250
18799693
19033399
19050248
19068129
19343206
19528657
19692655
20075939
20519450
20668922
20813840
20843799
20958798
21030605
21150295
21267068
21382375
21420385
21435446
21436055
21568942
21655085
22495310
22572820
22992961
23392696
23516531
23859941

Gene Ontology  (GO ID)

Biological Process

GO:0070588  calcium ion transmembrane transport
GO:0006816  calcium ion transport
GO:0060402  calcium ion transport into cytosol
GO:0071320  cellular response to cAMP
GO:0007204  elevation of cytosolic calcium ion concentration
GO:0007186  G-protein coupled receptor protein signaling pathway
GO:0048016  inositol phosphate-mediated signaling
GO:0006811  ion transport
GO:0060291  long-term synaptic potentiation
GO:0007613  memory
GO:0051291  protein heterooligomerization
GO:0051260  protein homooligomerization
GO:0051592  response to calcium ion
GO:0050913  sensory perception of bitter taste
GO:0050916  sensory perception of sweet taste
GO:0050917  sensory perception of umami taste
GO:0055085  transmembrane transport
GO:0006810  transport

Cellular Component

GO:0045177  apical part of cell
GO:0005903  brush border
GO:0043025  cell soma
GO:0005737  cytoplasm
GO:0030425  dendrite
GO:0005783  endoplasmic reticulum
GO:0005789  endoplasmic reticulum membrane
GO:0016021  integral to membrane
GO:0005887  integral to plasma membrane
GO:0016020  membrane
GO:0043209  myelin sheath
GO:0005635  nuclear envelope
GO:0005640  nuclear outer membrane
GO:0005730  nucleolus
GO:0005654  nucleoplasm
GO:0005634  nucleus
GO:0048471  perinuclear region of cytoplasm
GO:0005886  plasma membrane

Molecular Function

GO:0005262  calcium channel activity
GO:0005509  calcium ion binding
GO:0043533  inositol 1,3,4,5 tetrakisphosphate binding
GO:0070679  inositol 1,4,5 trisphosphate binding
GO:0005220  inositol 1,4,5-trisphosphate-sensitive calcium-release channel activity
GO:0000822  inositol hexakisphosphate binding
GO:0005218  intracellular ligand-gated calcium channel activity
GO:0005216  ion channel activity
GO:0035091  phosphoinositide binding
GO:0005515  protein binding