nuclear receptor coactivator 2

Synonym

glucocorticoid receptor-interacting protein 1, TIF2, NCoA-2, TIF-2, Ncoa2, TIF2/GRIP-1, Glucocorticoid receptor-interacting protein 1, Tif2, GRIP-1, SRC-2, D1Ertd433e, Nuclear receptor coactivator 2, Transcriptional intermediary factor 2, nuclear receptor coactivator 2, 9530095N19

normal 40 tissues
developmental tissues and primary cells（FANTOM5 CAGE）

Choropleth map on BodyParts3D

Choropleth maps on 3D human body images were generated by the relative gene expression values measured by GeneChip.

Classification in 40 Organs

brain

blood

connective

EST

cerebrum:19.10

cerebellum:55.30

brain stem:-

corpus callosum/glia:-

pineal gland:-

peripheral nerve:19.10

spine:-

retina:32.10

eye:7.60

artery/aorta:-

vein:-

lymphnode:10.80

peripheral blood:-

spleen:-

thymus:9.90

bone marrow:51.30

adipose:-

bone:12.50

skin:-

GeneChip

cerebrum:5.98

cerebellum:6.56

brain stem:-

corpus callosum/glia:-

pineal gland:-

peripheral nerve:5.82

spine:5.91

retina:5.42

eye:5.34

artery/aorta:-

vein:5.73

lymphnode:6.57

peripheral blood:-

spleen:6.67

thymus:-

bone marrow:6.67

adipose:6.04

bone:5.59

skin:5.37

CAGE

cerebrum:3.68

cerebellum:-

brain stem:3.12

corpus callosum/glia:-

pineal gland:-

peripheral nerve:-

spine:3.11

retina:-

eye:-

artery/aorta:3.36

vein:-

lymphnode:4.32

peripheral blood:-

spleen:3.26

thymus:3.68

bone marrow:-

adipose:-

bone:2.88

skin:3.55

RNA-seq

cerebrum:3.77

cerebellum:-

brain stem:-

corpus callosum/glia:-

pineal gland:-

peripheral nerve:-

spine:-

retina:-

eye:-

artery/aorta:-

vein:-

lymphnode:-

peripheral blood:-

spleen:-

thymus:-

bone marrow:-

adipose:-

bone:-

skin:-

reproductive

muscular

alimentary

liver

lung

urinary

endo/exo-crine

EST

uterus:-

placenta:13.80

prostate:61.80

ovary:160.90

testis:103.50

heart:-

muscle:-

esophagus:-

stomach:-

intestine:-

colon:-

liver/hepato:27.20

lung:30.10

bladder:-

kidney:-

pituitary:25.80

thyroid/parathyroid:-

adrenal gland:-

pancreas:75.10

breast:9.80

salivary:-

GeneChip

uterus:5.86

placenta:6.37

prostate:5.40

ovary:5.79

testis:7.65

heart:6.37

muscle:5.77

esophagus:-

stomach:5.88

intestine:5.87

colon:-

liver/hepato:6.37

lung:5.54

bladder:5.60

kidney:6.54

pituitary:6.19

thyroid/parathyroid:-

adrenal gland:5.34

pancreas:6.05

breast:5.81

salivary:5.88

CAGE

uterus:3.34

placenta:3.44

prostate:3.09

ovary:3.50

testis:2.55

heart:-

muscle:-

esophagus:-

stomach:2.26

intestine:2.98

colon:3.26

liver/hepato:3.15

lung:3.53

bladder:3.15

kidney:-

pituitary:3.64

thyroid/parathyroid:-

adrenal gland:3.32

pancreas:2.83

breast:2.95

salivary:-

RNA-seq

uterus:-

placenta:-

prostate:-

ovary:-

testis:-

heart:-

muscle:1.80

esophagus:-

stomach:-

intestine:-

colon:-

liver/hepato:6.72

lung:-

bladder:-

kidney:-

pituitary:-

thyroid/parathyroid:-

adrenal gland:-

pancreas:-

breast:-

salivary:-

IDs

Refseq ID	NM_008678
Gene ID	17978
Unigene ID	Mm.253721
Probe set ID	1450458_at [Mouse430_2]
Ensembl ID	ENSMUSG00000005886

Orthologous Gene

Human[3]	NM_006540
Rat[1]	NM_031822

Chromosomal Region

Gene Family (Interpro ID)

IPR000014

PAS

Gene Ontology (GO ID)

Biological Process

GO:0000122	negative regulation of transcription from RNA polymerase II promoter
GO:0045892	negative regulation of transcription, DNA-dependent
GO:0045925	positive regulation of female receptivity
GO:0045944	positive regulation of transcription from RNA polymerase II promoter
GO:0006355	regulation of transcription, DNA-dependent
GO:0007165	signal transduction
GO:0006351	transcription, DNA-dependent

Cellular Component

GO:0043025	cell soma
GO:0005737	cytoplasm
GO:0030425	dendrite
GO:0043197	dendritic spine
GO:0005794	Golgi apparatus
GO:0005874	microtubule
GO:0005634	nucleus
GO:0014069	postsynaptic density
GO:0048786	presynaptic active zone
GO:0005791	rough endoplasmic reticulum

Molecular Function

GO:0003682	chromatin binding
GO:0003677	DNA binding
GO:0070182	DNA polymerase binding
GO:0030331	estrogen receptor binding
GO:0035259	glucocorticoid receptor binding
GO:0004402	histone acetyltransferase activity
GO:0016922	ligand-dependent nuclear receptor binding
GO:0030374	ligand-dependent nuclear receptor transcription coactivator activity
GO:0035257	nuclear hormone receptor binding
GO:0030165	PDZ domain binding
GO:0033142	progesterone receptor binding
GO:0005515	protein binding
GO:0032403	protein complex binding
GO:0046983	protein dimerization activity
GO:0005102	receptor binding
GO:0042974	retinoic acid receptor binding
GO:0046965	retinoid X receptor binding
GO:0004871	signal transducer activity
GO:0046966	thyroid hormone receptor binding
GO:0030375	thyroid hormone receptor coactivator activity
GO:0003713	transcription coactivator activity

nuclear receptor coactivator 2

Synonym

Expression Pattern

Choropleth map on BodyParts3D

Classification in 40 Organs

Gene Information

IDs

Orthologous Gene

Chromosomal Region

Gene Family (Interpro ID)

Link to Pubmed (Pubmed ID)

Gene Ontology (GO ID)

Biological Process

Cellular Component

Molecular Function