natriuretic peptide receptor 1

Synonym

NPR-A, Pndr, AI893888, Atrial natriuretic peptide A-type receptor, guanylyl cyclase-A, GC-A, MGC117511, natriuretic peptide receptor 1, Npra, Npr1, NPRA

normal 40 tissues
developmental tissues and primary cells（FANTOM5 CAGE）

Choropleth map on BodyParts3D

Choropleth maps on 3D human body images were generated by the relative gene expression values measured by GeneChip.

Classification in 40 Organs

brain

blood

connective

EST

cerebrum:3.50

cerebellum:-

brain stem:-

corpus callosum/glia:-

pineal gland:-

peripheral nerve:-

spine:-

retina:-

eye:-

artery/aorta:-

vein:-

lymphnode:-

peripheral blood:-

spleen:-

thymus:-

bone marrow:-

adipose:-

bone:-

skin:47.50

GeneChip

cerebrum:3.89

cerebellum:4.08

brain stem:-

corpus callosum/glia:-

pineal gland:-

peripheral nerve:3.85

spine:3.93

retina:4.42

eye:4.23

artery/aorta:-

vein:4.30

lymphnode:4.25

peripheral blood:-

spleen:4.24

thymus:-

bone marrow:3.86

adipose:4.36

bone:3.88

skin:4.10

CAGE

cerebrum:1.65

cerebellum:-

brain stem:1.27

corpus callosum/glia:-

pineal gland:-

peripheral nerve:-

spine:1.47

retina:-

eye:-

artery/aorta:4.18

vein:-

lymphnode:2.11

peripheral blood:-

spleen:1.76

thymus:1.35

bone marrow:-

adipose:-

bone:2.59

skin:2.54

RNA-seq

cerebrum:1.99

cerebellum:-

brain stem:-

corpus callosum/glia:-

pineal gland:-

peripheral nerve:-

spine:-

retina:-

eye:-

artery/aorta:-

vein:-

lymphnode:-

peripheral blood:-

spleen:-

thymus:-

bone marrow:-

adipose:-

bone:-

skin:-

reproductive

muscular

alimentary

liver

lung

urinary

endo/exo-crine

EST

uterus:43.60

placenta:-

prostate:-

ovary:-

testis:14.80

heart:-

muscle:71

esophagus:-

stomach:-

intestine:-

colon:-

liver/hepato:18.10

lung:-

bladder:-

kidney:-

pituitary:-

thyroid/parathyroid:-

adrenal gland:-

pancreas:-

breast:3.30

salivary:-

GeneChip

uterus:4.50

placenta:4.26

prostate:4.10

ovary:4.71

testis:5.54

heart:4.64

muscle:4.30

esophagus:-

stomach:4.12

intestine:3.97

colon:-

liver/hepato:4.15

lung:5.03

bladder:4.09

kidney:4.47

pituitary:4.16

thyroid/parathyroid:-

adrenal gland:5.78

pancreas:4.54

breast:4.40

salivary:4.19

CAGE

uterus:3.50

placenta:2.38

prostate:1.35

ovary:4.03

testis:2.55

heart:-

muscle:-

esophagus:-

stomach:0.67

intestine:1.05

colon:1.19

liver/hepato:2.55

lung:4.13

bladder:2.62

kidney:-

pituitary:2.06

thyroid/parathyroid:-

adrenal gland:5.37

pancreas:2.83

breast:2.85

salivary:-

RNA-seq

uterus:-

placenta:-

prostate:-

ovary:-

testis:-

heart:-

muscle:2.01

esophagus:-

stomach:-

intestine:-

colon:-

liver/hepato:2.98

lung:-

bladder:-

kidney:-

pituitary:-

thyroid/parathyroid:-

adrenal gland:-

pancreas:-

breast:-

salivary:-

IDs

Refseq ID	NM_008727
Gene ID	18160
Unigene ID	Mm.46270
Probe set ID	1449160_at [Mouse430_2]
Ensembl ID	ENSMUSG00000027931

Orthologous Gene

Human[2]	NM_000906
Rat [0]

Chromosomal Region

Gene Family (Interpro ID)

IPR001828	Extracellular ligand-binding receptor
IPR001170	Natriuretic peptide receptor, N-terminal
IPR000719	Protein kinase, catalytic domain
IPR011009	Protein kinase-like domain
IPR002290	Serine/threonine-protein kinase domain
IPR017442	Serine/threonine-protein kinase-like domain
IPR001245	Tyrosine-protein kinase, catalytic domain
IPR020635	Tyrosine-protein kinase, subgroup, catalytic domain

Gene Ontology (GO ID)

Biological Process

GO:0007166	cell surface receptor linked signal transduction
GO:0006182	cGMP biosynthetic process
GO:0009190	cyclic nucleotide biosynthetic process
GO:0042417	dopamine metabolic process
GO:0048662	negative regulation of smooth muscle cell proliferation
GO:0030828	positive regulation of cGMP biosynthetic process
GO:0006468	protein amino acid phosphorylation
GO:0007168	receptor guanylyl cyclase signaling pathway
GO:0008217	regulation of blood pressure
GO:0050880	regulation of blood vessel size

Cellular Component

GO:0016021	integral to membrane
GO:0016020	membrane
GO:0005886	plasma membrane

Molecular Function

GO:0005524	ATP binding
GO:0005525	GTP binding
GO:0004383	guanylate cyclase activity
GO:0042562	hormone binding
GO:0016829	lyase activity
GO:0016941	natriuretic peptide receptor activity
GO:0000166	nucleotide binding
GO:0017046	peptide hormone binding
GO:0016849	phosphorus-oxygen lyase activity
GO:0004672	protein kinase activity
GO:0019901	protein kinase binding
GO:0016772	transferase activity, transferring phosphorus-containing groups

natriuretic peptide receptor 1

Synonym

Expression Pattern

Choropleth map on BodyParts3D

Classification in 40 Organs

Gene Information

IDs

Orthologous Gene

Chromosomal Region

Gene Family (Interpro ID)

Link to Pubmed (Pubmed ID)

Gene Ontology (GO ID)

Biological Process

Cellular Component

Molecular Function