phosphodiesterase 9A

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Synonym

Pde8b, PDE9A1, phosphodiesterase 9A, Pde9a

Expression Pattern

Choropleth map on BodyParts3D

Choropleth maps on 3D human body images were generated by the relative gene expression values measured by GeneChip.

Classification in 40 Organs

brain blood connective
EST cerebrum:34.70 cerebellum:73.70 brain stem:127.10 corpus callosum/glia:- pineal gland:- peripheral nerve:38.20 spine:47.30 retina:32.10 eye:- artery/aorta:- vein:- lymphnode:- peripheral blood:- spleen:13.20 thymus:19.80 bone marrow:- adipose:- bone:- skin:23.80
GeneChip cerebrum:6.42 cerebellum:8.08 brain stem:- corpus callosum/glia:- pineal gland:- peripheral nerve:4.72 spine:6.17 retina:5.69 eye:5.81 artery/aorta:- vein:5.35 lymphnode:4.41 peripheral blood:- spleen:4.52 thymus:- bone marrow:4.47 adipose:5.36 bone:4.37 skin:4.94
CAGE cerebrum:3.16 cerebellum:- brain stem:2.54 corpus callosum/glia:- pineal gland:- peripheral nerve:- spine:2.79 retina:- eye:- artery/aorta:1.06 vein:- lymphnode:0.57 peripheral blood:- spleen:0 thymus:0 bone marrow:- adipose:- bone:0 skin:1.57
RNA-seq cerebrum:4.27 cerebellum:- brain stem:- corpus callosum/glia:- pineal gland:- peripheral nerve:- spine:- retina:- eye:- artery/aorta:- vein:- lymphnode:- peripheral blood:- spleen:- thymus:- bone marrow:- adipose:- bone:- skin:-
reproductive muscular alimentary liver lung urinary endo/exo-crine
EST uterus:87.20 placenta:69 prostate:- ovary:23 testis:14.80 heart:18.60 muscle:- esophagus:- stomach:32.70 intestine:37 colon:176.20     liver/hepato:-        lung:-    bladder:- kidney:40.30 pituitary:51.70 thyroid/parathyroid:112.50 adrenal gland:- pancreas:- breast:16.30 salivary:-
GeneChip uterus:5.96 placenta:6.60 prostate:7.90 ovary:4.85 testis:5.04 heart:4.94 muscle:4.77 esophagus:- stomach:7.44 intestine:8.99 colon:- liver/hepato:7.42 lung:7.50 bladder:6.52 kidney:7.22 pituitary:6.60 thyroid/parathyroid:- adrenal gland:4.84 pancreas:5.53 breast:6.19 salivary:5.06
CAGE uterus:2.35 placenta:2.25 prostate:4.09 ovary:1.55 testis:1.97 heart:- muscle:- esophagus:- stomach:1.75 intestine:3.84 colon:4.68     liver/hepato:2.64    lung:3.58 bladder:2.70 kidney:- pituitary:2.45 thyroid/parathyroid:- adrenal gland:0.64 pancreas:1.84 breast:2.27 salivary:-
RNA-seq uterus:- placenta:- prostate:- ovary:- testis:- heart:- muscle:1.21 esophagus:- stomach:- intestine:- colon:-     liver/hepato:3.90        lung:-    bladder:- kidney:- pituitary:- thyroid/parathyroid:- adrenal gland:- pancreas:- breast:- salivary:-

Gene Information

IDs

Refseq ID NM_008804
Gene ID 18585
Unigene ID Mm.10812
Probe set ID 1449403_at  [Mouse430_2]
Ensembl ID ENSMUSG00000041119

Orthologous Gene

Human[20]  NM_001001567, NM_001001568, NM_001001569, NM_001001570, NM_001001571, NM_001001572, NM_001001573, NM_001001574, NM_001001575, NM_001001576, NM_001001577, NM_001001578, NM_001001579, NM_001001580, NM_001001581, NM_001001582, NM_001001583, NM_001001584, NM_001001585, NM_002606
Rat[1]  NM_138543, NM_001001568, NM_001001569, NM_001001570, NM_001001571, NM_001001572, NM_001001573, NM_001001574, NM_001001575, NM_001001576, NM_001001577, NM_001001578, NM_001001579, NM_001001580, NM_001001581, NM_001001582, NM_001001583, NM_001001584, NM_001001585, NM_002606

Chromosomal Region

17B1  [31,523,179  -  31,613,255]

Gene Family (Interpro ID)

IPR003607  Metal-dependent phosphohydrolase, HD domain

Link to Pubmed  (Pubmed ID)

9624145
9624146
9856478
10349636
11042159
11076861
11217851
12466851
12466854
12466855
12477932
14610273
14681479
15489334
16141072
16141073
16602821
17307970
18799693
21267068
22596207
24154525

Gene Ontology  (GO ID)

Biological Process

GO:0008152  metabolic process
GO:0007165  signal transduction

Cellular Component

GO:0043204  perikaryon

Molecular Function

GO:0047555  3',5'-cyclic-GMP phosphodiesterase activity
GO:0004114  3',5'-cyclic-nucleotide phosphodiesterase activity
GO:0003824  catalytic activity
GO:0016787  hydrolase activity
GO:0046872  metal ion binding
GO:0008081  phosphoric diester hydrolase activity