chemokine (C-C motif) ligand 12

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Synonym

Ccl12, Monocyte chemotactic protein 5, MCP-1-related chemokine, MCP-5, chemokine (C-C motif) ligand 12, Mcp5, Scya12, CCL12, Small inducible cytokine A12 precursor

Expression Pattern

Choropleth map on BodyParts3D

Choropleth maps on 3D human body images were generated by the relative gene expression values measured by GeneChip.

Classification in 40 Organs

brain blood connective
EST cerebrum:17.40 cerebellum:18.40 brain stem:- corpus callosum/glia:- pineal gland:- peripheral nerve:- spine:- retina:32.10 eye:38 artery/aorta:- vein:- lymphnode:- peripheral blood:- spleen:- thymus:- bone marrow:- adipose:- bone:12.50 skin:7.90
GeneChip nodata
CAGE nodata
RNA-seq nodata
reproductive muscular alimentary liver lung urinary endo/exo-crine
EST uterus:- placenta:- prostate:30.90 ovary:- testis:29.60 heart:- muscle:- esophagus:- stomach:- intestine:- colon:-     liver/hepato:27.20        lung:10    bladder:- kidney:- pituitary:- thyroid/parathyroid:- adrenal gland:- pancreas:18.80 breast:19.60 salivary:-
GeneChip nodata
CAGE nodata
RNA-seq nodata

Gene Information

IDs

Refseq ID XM_001480893
Gene ID 20293
Unigene ID Mm.86705
Probe set ID -
Ensembl ID -

Orthologous Gene

Human [0]  
Rat [0]  

Chromosomal Region

11C  [81,915,347  -  81,916,902]

Gene Family (Interpro ID)

IPR001811  Small chemokine, interleukin-8-like

Link to Pubmed  (Pubmed ID)

8920881
8996246
10349636
10438970
10995569
11042159
11076861
11217851
11735217
12080938
12466851
12477932
15489334
16141072
16141073
16602821
17364026
18334747
20234092
20931267
21217759
21677750
22814601
23033370
24458145
24477914

Gene Ontology  (GO ID)

Biological Process

GO:0001525  angiogenesis
GO:0043615  astrocyte cell migration
GO:0071407  cellular response to organic cyclic substance
GO:0006935  chemotaxis
GO:0019221  cytokine-mediated signaling pathway
GO:0007010  cytoskeleton organization
GO:0006955  immune response
GO:0006954  inflammatory response
GO:0031663  lipopolysaccharide-mediated signaling pathway
GO:0048246  macrophage chemotaxis
GO:0000165  MAPKKK cascade
GO:0002548  monocyte chemotaxis
GO:0034351  negative regulation of glial cell apoptosis
GO:0043524  negative regulation of neuron apoptosis
GO:0043491  protein kinase B signaling cascade
GO:0008360  regulation of cell shape

Cellular Component

GO:0005576  extracellular region
GO:0005615  extracellular space

Molecular Function

GO:0031727  CCR2 chemokine receptor binding
GO:0008009  chemokine activity
GO:0005125  cytokine activity