sorbin and SH3 domain containing 3

 jump to detail

Synonym

SH3 domain-containing protein SH3P3, sorbin and SH3 domain containing 3, Sorbs3, SH3-containing adapter molecule 1, vinexin alpha, Scam1, Vinexin, Sorbin and SH3 domain-containing protein 3, vinexin beta, Sh3d4, SH3P3, SCAM-1, vinexin-g

Expression Pattern

Choropleth map on BodyParts3D

Choropleth maps on 3D human body images were generated by the relative gene expression values measured by GeneChip.

Classification in 40 Organs

brain blood connective
EST cerebrum:5.20 cerebellum:36.80 brain stem:- corpus callosum/glia:- pineal gland:- peripheral nerve:- spine:- retina:- eye:7.60 artery/aorta:84.40 vein:- lymphnode:- peripheral blood:- spleen:- thymus:19.80 bone marrow:- adipose:- bone:37.60 skin:7.90
GeneChip cerebrum:7.28 cerebellum:7.37 brain stem:- corpus callosum/glia:- pineal gland:- peripheral nerve:7.86 spine:8.36 retina:8.33 eye:7.78 artery/aorta:- vein:8.47 lymphnode:7.25 peripheral blood:- spleen:7.45 thymus:- bone marrow:6.52 adipose:7.80 bone:6.93 skin:7.53
CAGE cerebrum:3.21 cerebellum:- brain stem:3.59 corpus callosum/glia:- pineal gland:- peripheral nerve:- spine:4.01 retina:- eye:- artery/aorta:3.78 vein:- lymphnode:2.94 peripheral blood:- spleen:1.69 thymus:1.43 bone marrow:- adipose:- bone:2.45 skin:3.03
RNA-seq cerebrum:4.29 cerebellum:- brain stem:- corpus callosum/glia:- pineal gland:- peripheral nerve:- spine:- retina:- eye:- artery/aorta:- vein:- lymphnode:- peripheral blood:- spleen:- thymus:- bone marrow:- adipose:- bone:- skin:-
reproductive muscular alimentary liver lung urinary endo/exo-crine
EST uterus:- placenta:13.80 prostate:- ovary:- testis:22.20 heart:- muscle:71 esophagus:- stomach:32.70 intestine:- colon:35.20     liver/hepato:18.10        lung:30.10    bladder:- kidney:16.10 pituitary:- thyroid/parathyroid:- adrenal gland:- pancreas:- breast:13.10 salivary:54
GeneChip uterus:8.32 placenta:8.93 prostate:8.19 ovary:8.56 testis:8.66 heart:8.30 muscle:8.76 esophagus:- stomach:8.09 intestine:7.04 colon:- liver/hepato:7.80 lung:10.30 bladder:8.09 kidney:7.67 pituitary:8.21 thyroid/parathyroid:- adrenal gland:8.99 pancreas:8.35 breast:8.15 salivary:8.53
CAGE uterus:3.28 placenta:3.94 prostate:2.37 ovary:3.73 testis:4.80 heart:- muscle:- esophagus:- stomach:3.69 intestine:1.29 colon:1.52     liver/hepato:2.70    lung:4.09 bladder:3.09 kidney:- pituitary:2.73 thyroid/parathyroid:- adrenal gland:4.01 pancreas:3.61 breast:1.90 salivary:-
RNA-seq uterus:- placenta:- prostate:- ovary:- testis:- heart:- muscle:6.10 esophagus:- stomach:- intestine:- colon:-     liver/hepato:5.63        lung:-    bladder:- kidney:- pituitary:- thyroid/parathyroid:- adrenal gland:- pancreas:- breast:- salivary:-

Gene Information

IDs

Refseq ID NM_011366
Gene ID 20410
Unigene ID Mm.5068
Probe set ID 1419329_at  [Mouse430_2]
Ensembl ID ENSMUSG00000022091

Orthologous Gene

Human[4]  NM_001018003, NM_005775
Rat[1]  NM_001005762, NM_005775

Chromosomal Region

-

Gene Family (Interpro ID)

-

Link to Pubmed  (Pubmed ID)

9630982
9885244
10087302
10349636
11042159
11076861
11125038
11217851
11472845
11825889
12466851
12477932
12657639
15184391
15242778
15734736
15782199
15836771
15901664
16126177
16141072
16141073
16302969
17582013
19217206
19389355
19580787
20361963
20634350
21267068

Gene Ontology  (GO ID)

Biological Process

GO:0007155  cell adhesion
GO:0031589  cell-substrate adhesion
GO:0000122  negative regulation of transcription from RNA polymerase II promoter
GO:0043410  positive regulation of MAPKKK cascade
GO:0051496  positive regulation of stress fiber formation

Cellular Component

GO:0030054  cell junction
GO:0005737  cytoplasm
GO:0005856  cytoskeleton
GO:0005925  focal adhesion
GO:0005634  nucleus

Molecular Function

GO:0005515  protein binding
GO:0008134  transcription factor binding
GO:0017166  vinculin binding