TRAF-interacting protein with forkhead-associated domain

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Synonym

Traf2 binding protein, TIFA, T2bp

Expression Pattern

Choropleth map on BodyParts3D

Choropleth maps on 3D human body images were generated by the relative gene expression values measured by GeneChip.

Classification in 40 Organs

brain blood connective
EST cerebrum:5.20 cerebellum:36.80 brain stem:- corpus callosum/glia:- pineal gland:- peripheral nerve:95.50 spine:47.30 retina:128.60 eye:- artery/aorta:- vein:- lymphnode:21.60 peripheral blood:100.60 spleen:92.20 thymus:39.50 bone marrow:333.40 adipose:- bone:25 skin:-
GeneChip cerebrum:6.11 cerebellum:5.32 brain stem:- corpus callosum/glia:- pineal gland:- peripheral nerve:7.47 spine:6.48 retina:7.12 eye:6.29 artery/aorta:- vein:6.01 lymphnode:9.27 peripheral blood:- spleen:8.52 thymus:- bone marrow:10.49 adipose:6.09 bone:10.37 skin:6.33
CAGE cerebrum:1.41 cerebellum:- brain stem:1.60 corpus callosum/glia:- pineal gland:- peripheral nerve:- spine:1.23 retina:- eye:- artery/aorta:2.05 vein:- lymphnode:3.43 peripheral blood:- spleen:3.17 thymus:1.35 bone marrow:- adipose:- bone:4.08 skin:1.84
RNA-seq cerebrum:1.06 cerebellum:- brain stem:- corpus callosum/glia:- pineal gland:- peripheral nerve:- spine:- retina:- eye:- artery/aorta:- vein:- lymphnode:- peripheral blood:- spleen:- thymus:- bone marrow:- adipose:- bone:- skin:-
reproductive muscular alimentary liver lung urinary endo/exo-crine
EST uterus:- placenta:13.80 prostate:30.90 ovary:11.50 testis:22.20 heart:- muscle:- esophagus:- stomach:- intestine:37 colon:-     liver/hepato:45.30        lung:10    bladder:- kidney:24.20 pituitary:- thyroid/parathyroid:- adrenal gland:- pancreas:- breast:49 salivary:-
GeneChip uterus:7.48 placenta:5.87 prostate:6.34 ovary:6.70 testis:5.69 heart:5.92 muscle:5.86 esophagus:- stomach:7.70 intestine:9.74 colon:- liver/hepato:7.82 lung:6.53 bladder:6.77 kidney:6.45 pituitary:8.54 thyroid/parathyroid:- adrenal gland:5.99 pancreas:6.72 breast:6.20 salivary:8.45
CAGE uterus:1.78 placenta:0.79 prostate:0.74 ovary:1.69 testis:1.34 heart:- muscle:- esophagus:- stomach:1.91 intestine:2.89 colon:2.53     liver/hepato:2.58    lung:2.13 bladder:1.73 kidney:- pituitary:2.66 thyroid/parathyroid:- adrenal gland:1.89 pancreas:1.84 breast:1.27 salivary:-
RNA-seq uterus:- placenta:- prostate:- ovary:- testis:- heart:- muscle:0.99 esophagus:- stomach:- intestine:- colon:-     liver/hepato:2.25        lung:-    bladder:- kidney:- pituitary:- thyroid/parathyroid:- adrenal gland:- pancreas:- breast:- salivary:-

Gene Information

IDs

Refseq ID NM_145133
Gene ID 211550
Unigene ID Mm.31852
Probe set ID 1426501_a_at  [Mouse430_2]
Ensembl ID ENSMUSG00000046688

Orthologous Gene

Human[1]  NM_052864
Rat[1]  NM_001014044

Chromosomal Region

-

Gene Family (Interpro ID)

IPR000253  Forkhead-associated
IPR008984  SMAD/FHA domain

Link to Pubmed  (Pubmed ID)

8889548
10349636
11042159
11076861
11217851
11798190
12466851
12477932
12566447
16141072
16141073
16643855
21267068
21677750
23722163

Gene Ontology  (GO ID)

Biological Process

GO:0007249  I-kappaB kinase/NF-kappaB cascade

Molecular Function

GO:0005515  protein binding