T-cell acute lymphocytic leukemia 1

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Synonym

Stem cell protein, Tal-1, Scl, Tal1, SCL/tal-1, T-cell acute lymphocytic leukemia 1, tal-1, TAL-1 protein

Choropleth map on BodyParts3D

Choropleth maps on 3D human body images were generated by the relative gene expression values measured by GeneChip.

Classification in 40 Organs

brain blood connective
EST cerebrum:8.70 cerebellum:- brain stem:- corpus callosum/glia:- pineal gland:- peripheral nerve:- spine:- retina:- eye:- artery/aorta:- vein:- lymphnode:54 peripheral blood:28.80 spleen:- thymus:- bone marrow:12.80 adipose:- bone:- skin:-
GeneChip cerebrum:4.42 cerebellum:4.28 brain stem:- corpus callosum/glia:- pineal gland:- peripheral nerve:4.30 spine:4.92 retina:4.19 eye:4.44 artery/aorta:- vein:5.23 lymphnode:5.42 peripheral blood:- spleen:6.93 thymus:- bone marrow:10.85 adipose:4.70 bone:10.06 skin:4.67
CAGE cerebrum:0.48 cerebellum:- brain stem:1.35 corpus callosum/glia:- pineal gland:- peripheral nerve:- spine:0.91 retina:- eye:- artery/aorta:1.59 vein:- lymphnode:1.28 peripheral blood:- spleen:5.23 thymus:0 bone marrow:- adipose:- bone:4.50 skin:0.97
RNA-seq cerebrum:1.03 cerebellum:- brain stem:- corpus callosum/glia:- pineal gland:- peripheral nerve:- spine:- retina:- eye:- artery/aorta:- vein:- lymphnode:- peripheral blood:- spleen:- thymus:- bone marrow:- adipose:- bone:- skin:-
reproductive muscular alimentary liver lung urinary endo/exo-crine
EST uterus:- placenta:- prostate:- ovary:- testis:22.20 heart:- muscle:- esophagus:- stomach:- intestine:- colon:-     liver/hepato:9.10        lung:-    bladder:- kidney:- pituitary:- thyroid/parathyroid:- adrenal gland:- pancreas:- breast:3.30 salivary:-
GeneChip uterus:4.77 placenta:4.44 prostate:4.58 ovary:4.68 testis:4.11 heart:5.61 muscle:4.75 esophagus:- stomach:4.45 intestine:4.37 colon:- liver/hepato:4.90 lung:7 bladder:4.75 kidney:4.61 pituitary:4.23 thyroid/parathyroid:- adrenal gland:4.84 pancreas:4.50 breast:4.59 salivary:4.56
CAGE uterus:1.10 placenta:1.18 prostate:0.37 ovary:0.76 testis:0 heart:- muscle:- esophagus:- stomach:0.67 intestine:0.72 colon:0.23     liver/hepato:0.47    lung:2.38 bladder:0.93 kidney:- pituitary:0.70 thyroid/parathyroid:- adrenal gland:0.91 pancreas:0.84 breast:0.69 salivary:-
RNA-seq uterus:- placenta:- prostate:- ovary:- testis:- heart:- muscle:1.12 esophagus:- stomach:- intestine:- colon:-     liver/hepato:1.68        lung:-    bladder:- kidney:- pituitary:- thyroid/parathyroid:- adrenal gland:- pancreas:- breast:- salivary:-

IDs

Refseq ID NM_011527
Gene ID 21349
Unigene ID Mm.439685
Probe set ID 1449389_at  [Mouse430_2]
Ensembl ID ENSMUSG00000028717

Orthologous Gene

Human[2]  NM_003189
Rat[1]  NM_001107958

Chromosomal Region

-

Gene Family (Interpro ID)

-

Link to Pubmed  (Pubmed ID)

Gene Ontology  (GO ID)

Biological Process

GO:0001525  angiogenesis
GO:0060018  astrocyte fate commitment
GO:0030154  cell differentiation
GO:0045165  cell fate commitment
GO:0060216  definitive hemopoiesis
GO:0035162  embryonic hemopoiesis
GO:0030218  erythrocyte differentiation
GO:0043249  erythrocyte maturation
GO:0048699  generation of neurons
GO:0060217  hemangioblast cell differentiation
GO:0030097  hemopoiesis
GO:0060218  hemopoietic stem cell differentiation
GO:0007626  locomotory behavior
GO:0030219  megakaryocyte differentiation
GO:0007275  multicellular organismal development
GO:0030099  myeloid cell differentiation
GO:0000122  negative regulation of transcription from RNA polymerase II promoter
GO:0030182  neuron differentiation
GO:0030220  platelet formation
GO:0051781  positive regulation of cell division
GO:0045799  positive regulation of chromatin assembly or disassembly
GO:0045648  positive regulation of erythrocyte differentiation
GO:0045931  positive regulation of mitotic cell cycle
GO:0031334  positive regulation of protein complex assembly
GO:0045944  positive regulation of transcription from RNA polymerase II promoter
GO:0045893  positive regulation of transcription, DNA-dependent
GO:0042127  regulation of cell proliferation
GO:0060375  regulation of mast cell differentiation
GO:0045637  regulation of myeloid cell differentiation
GO:0006357  regulation of transcription from RNA polymerase II promoter
GO:0006355  regulation of transcription, DNA-dependent
GO:0021527  spinal cord association neuron differentiation
GO:0006351  transcription, DNA-dependent

Cellular Component

GO:0000118  histone deacetylase complex
GO:0033193  Lsd1/2 complex
GO:0000790  nuclear chromatin
GO:0005634  nucleus
GO:0043234  protein complex
GO:0005667  transcription factor complex

Molecular Function

GO:0003682  chromatin binding
GO:0003677  DNA binding
GO:0044212  DNA regulatory region binding
GO:0070888  E-box binding
GO:0019899  enzyme binding
GO:0042826  histone deacetylase binding
GO:0005515  protein binding
GO:0046983  protein dimerization activity
GO:0046982  protein heterodimerization activity
GO:0003700  transcription factor activity