urotensin 2 receptor

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Synonym

urotensin 2 receptor, Gpr14, Uts2r, UR-II-R, Urotensin II receptor, urotensin II receptor, UTR2, UTR, G-protein coupled receptor 14

Expression Pattern

Choropleth map on BodyParts3D

Choropleth maps on 3D human body images were generated by the relative gene expression values measured by GeneChip.

Classification in 40 Organs

brain blood connective
EST cerebrum:- cerebellum:- brain stem:- corpus callosum/glia:- pineal gland:- peripheral nerve:- spine:- retina:- eye:- artery/aorta:- vein:- lymphnode:- peripheral blood:- spleen:- thymus:- bone marrow:- adipose:- bone:- skin:-
GeneChip cerebrum:4.27 cerebellum:4.56 brain stem:- corpus callosum/glia:- pineal gland:- peripheral nerve:4.36 spine:4.36 retina:4.49 eye:4.79 artery/aorta:- vein:4.32 lymphnode:4.42 peripheral blood:- spleen:4.25 thymus:- bone marrow:4.48 adipose:4.43 bone:4.55 skin:4.53
CAGE nodata
RNA-seq cerebrum:0.93 cerebellum:- brain stem:- corpus callosum/glia:- pineal gland:- peripheral nerve:- spine:- retina:- eye:- artery/aorta:- vein:- lymphnode:- peripheral blood:- spleen:- thymus:- bone marrow:- adipose:- bone:- skin:-
reproductive muscular alimentary liver lung urinary endo/exo-crine
EST uterus:- placenta:- prostate:- ovary:- testis:- heart:- muscle:- esophagus:- stomach:- intestine:- colon:-     liver/hepato:-        lung:-    bladder:- kidney:- pituitary:38.80 thyroid/parathyroid:- adrenal gland:- pancreas:- breast:- salivary:-
GeneChip uterus:4.23 placenta:4.98 prostate:4.43 ovary:3.94 testis:4.28 heart:4.85 muscle:4.90 esophagus:- stomach:4.42 intestine:4.44 colon:- liver/hepato:4.52 lung:4.11 bladder:4.17 kidney:4.66 pituitary:4.68 thyroid/parathyroid:- adrenal gland:4.10 pancreas:4.90 breast:4.55 salivary:4.35
CAGE nodata
RNA-seq uterus:- placenta:- prostate:- ovary:- testis:- heart:- muscle:0.81 esophagus:- stomach:- intestine:- colon:-     liver/hepato:0        lung:-    bladder:- kidney:- pituitary:- thyroid/parathyroid:- adrenal gland:- pancreas:- breast:- salivary:-

Gene Information

IDs

Refseq ID NM_145440
Gene ID 217369
Unigene ID Mm.20122
Probe set ID 1451863_at  [Mouse430_2]
Ensembl ID ENSMUSG00000039321

Orthologous Gene

Human[1]  NM_018949
Rat [0]  

Chromosomal Region

-

Gene Family (Interpro ID)

IPR000276  7TM GPCR, rhodopsin-like
IPR017452  GPCR, rhodopsin-like superfamily
IPR002286  P2 purinoceptor
IPR000670  Urotensin II receptor

Link to Pubmed  (Pubmed ID)

12466851
12477932
12770952
16325305
16602821
18710417
19323985
19696412
20620192
21267068
21369867
21677750
24297699

Gene Ontology  (GO ID)

Biological Process

GO:0007204  elevation of cytosolic calcium ion concentration
GO:0007186  G-protein coupled receptor protein signaling pathway
GO:0045776  negative regulation of blood pressure
GO:0003105  negative regulation of glomerular filtration
GO:0045766  positive regulation of angiogenesis
GO:0045777  positive regulation of blood pressure
GO:0030307  positive regulation of cell growth
GO:0046005  positive regulation of circadian sleep/wake cycle, REM sleep
GO:0010841  positive regulation of circadian sleep/wake cycle, wakefulness
GO:0048146  positive regulation of fibroblast proliferation
GO:0045907  positive regulation of vasoconstriction
GO:0008217  regulation of blood pressure
GO:0042312  regulation of vasodilation
GO:0007165  signal transduction

Cellular Component

GO:0005769  early endosome
GO:0016021  integral to membrane
GO:0016020  membrane
GO:0005886  plasma membrane
GO:0055037  recycling endosome

Molecular Function

GO:0004930  G-protein coupled receptor activity
GO:0004871  signal transducer activity
GO:0001604  urotensin II receptor activity