tubby-like protein 3

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Synonym

Tulp3, Tubby-related protein 3, tubby-like protein 3, Tubby-like protein 3, AI316887, 2310022L06Rik

Expression Pattern

Choropleth map on BodyParts3D

Choropleth maps on 3D human body images were generated by the relative gene expression values measured by GeneChip.

Classification in 40 Organs

brain blood connective
EST cerebrum:20.80 cerebellum:18.40 brain stem:- corpus callosum/glia:- pineal gland:- peripheral nerve:114.70 spine:- retina:32.10 eye:45.60 artery/aorta:- vein:- lymphnode:- peripheral blood:- spleen:26.30 thymus:29.60 bone marrow:25.60 adipose:- bone:62.60 skin:332.50
GeneChip cerebrum:7.15 cerebellum:7.71 brain stem:- corpus callosum/glia:- pineal gland:- peripheral nerve:7.68 spine:7.47 retina:7.86 eye:8.57 artery/aorta:- vein:7.93 lymphnode:6.58 peripheral blood:- spleen:6.73 thymus:- bone marrow:5.75 adipose:7.08 bone:5.85 skin:6.92
CAGE cerebrum:3.21 cerebellum:- brain stem:2.99 corpus callosum/glia:- pineal gland:- peripheral nerve:- spine:3.15 retina:- eye:- artery/aorta:2.42 vein:- lymphnode:2.43 peripheral blood:- spleen:1.73 thymus:3.11 bone marrow:- adipose:- bone:1.69 skin:3.23
RNA-seq cerebrum:2.33 cerebellum:- brain stem:- corpus callosum/glia:- pineal gland:- peripheral nerve:- spine:- retina:- eye:- artery/aorta:- vein:- lymphnode:- peripheral blood:- spleen:- thymus:- bone marrow:- adipose:- bone:- skin:-
reproductive muscular alimentary liver lung urinary endo/exo-crine
EST uterus:- placenta:13.80 prostate:- ovary:114.90 testis:- heart:111.60 muscle:- esophagus:- stomach:- intestine:37 colon:17.60     liver/hepato:18.10        lung:40.20    bladder:198.50 kidney:40.30 pituitary:193.80 thyroid/parathyroid:- adrenal gland:- pancreas:- breast:55.50 salivary:-
GeneChip uterus:7.87 placenta:6.32 prostate:7.83 ovary:8.53 testis:6.41 heart:6.83 muscle:6.94 esophagus:- stomach:6.54 intestine:6.01 colon:- liver/hepato:5.50 lung:7.94 bladder:7.53 kidney:8.85 pituitary:8.60 thyroid/parathyroid:- adrenal gland:8.60 pancreas:5.75 breast:6.95 salivary:6.79
CAGE uterus:2.86 placenta:2.41 prostate:3.13 ovary:3.46 testis:1.89 heart:- muscle:- esophagus:- stomach:1.91 intestine:1.43 colon:1.03     liver/hepato:1.22    lung:3.10 bladder:2.91 kidney:- pituitary:3.60 thyroid/parathyroid:- adrenal gland:3.51 pancreas:1.61 breast:2.97 salivary:-
RNA-seq uterus:- placenta:- prostate:- ovary:- testis:- heart:- muscle:1.36 esophagus:- stomach:- intestine:- colon:-     liver/hepato:1.68        lung:-    bladder:- kidney:- pituitary:- thyroid/parathyroid:- adrenal gland:- pancreas:- breast:- salivary:-

Gene Information

IDs

Refseq ID NM_011657
Gene ID 22158
Unigene ID Mm.291783
Probe set ID 1449008_at  [Mouse430_2]
Ensembl ID ENSMUSG00000001521

Orthologous Gene

Human[3]  NM_001160408, NM_003324
Rat[3]  NM_001160408, NM_003324

Chromosomal Region

-

Gene Family (Interpro ID)

-

Link to Pubmed  (Pubmed ID)

9828123
10349636
10922068
11042159
11076861
11217851
11406614
11483369
11595174
12466851
12477932
14610273
15489334
15782199
16141072
16141073
17967808
18799693
19223390
19286674
19334287
20889716
21209331
21267068

Gene Ontology  (GO ID)

Biological Process

GO:0007420  brain development
GO:0060434  bronchus morphogenesis
GO:0021953  central nervous system neuron differentiation
GO:0021904  dorsal/ventral neural tube patterning
GO:0031076  embryonic camera-type eye development
GO:0042733  embryonic digit morphogenesis
GO:0048702  embryonic neurocranium morphogenesis
GO:0001701  in utero embryonic development
GO:0060173  limb development
GO:0007275  multicellular organismal development
GO:0045879  negative regulation of smoothened signaling pathway
GO:0021914  negative regulation of smoothened signaling pathway involved in ventral spinal cord patterning
GO:0001843  neural tube closure
GO:0021915  neural tube development
GO:0008277  regulation of G-protein coupled receptor protein signaling pathway
GO:0008589  regulation of smoothened signaling pathway
GO:0060831  smoothened signaling pathway involved in dorsal/ventral neural tube patterning

Cellular Component

GO:0042995  cell projection
GO:0005929  cilium
GO:0035085  cilium axoneme
GO:0005737  cytoplasm
GO:0005576  extracellular region
GO:0030991  intraflagellar transport particle A
GO:0016020  membrane
GO:0005634  nucleus
GO:0005886  plasma membrane

Molecular Function

GO:0035091  phosphoinositide binding