U2 small nuclear ribonucleoprotein auxiliary factor (U2AF) 2

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Synonym

U2af2, MGC118033, U2af65, U2 snRNP auxiliary factor large subunit, U2 auxiliary factor 65 kDa subunit, Splicing factor U2AF 65 kDa subunit

Expression Pattern

Choropleth map on BodyParts3D

Choropleth maps on 3D human body images were generated by the relative gene expression values measured by GeneChip.

Classification in 40 Organs

brain blood connective
EST cerebrum:119.80 cerebellum:36.80 brain stem:- corpus callosum/glia:- pineal gland:- peripheral nerve:133.80 spine:283.70 retina:64.30 eye:76 artery/aorta:- vein:- lymphnode:54 peripheral blood:- spleen:197.50 thymus:118.60 bone marrow:12.80 adipose:212.70 bone:112.70 skin:102.90
GeneChip cerebrum:9.93 cerebellum:9.92 brain stem:- corpus callosum/glia:- pineal gland:- peripheral nerve:9.72 spine:9.69 retina:9.86 eye:9.87 artery/aorta:- vein:9.42 lymphnode:10.27 peripheral blood:- spleen:10.61 thymus:- bone marrow:10.34 adipose:9.43 bone:9.77 skin:9.53
CAGE cerebrum:4.12 cerebellum:- brain stem:4.06 corpus callosum/glia:- pineal gland:- peripheral nerve:- spine:4.07 retina:- eye:- artery/aorta:3.70 vein:- lymphnode:4.79 peripheral blood:- spleen:4.53 thymus:4.63 bone marrow:- adipose:- bone:4.29 skin:4.46
RNA-seq cerebrum:41.84 cerebellum:- brain stem:- corpus callosum/glia:- pineal gland:- peripheral nerve:- spine:- retina:- eye:- artery/aorta:- vein:- lymphnode:- peripheral blood:- spleen:- thymus:- bone marrow:- adipose:- bone:- skin:-
reproductive muscular alimentary liver lung urinary endo/exo-crine
EST uterus:87.20 placenta:55.20 prostate:- ovary:11.50 testis:36.90 heart:- muscle:- esophagus:- stomach:- intestine:- colon:52.90     liver/hepato:9.10        lung:190.80    bladder:- kidney:48.40 pituitary:297.10 thyroid/parathyroid:- adrenal gland:- pancreas:56.30 breast:62 salivary:54
GeneChip uterus:10.23 placenta:9.43 prostate:9.91 ovary:10.11 testis:9.44 heart:9.44 muscle:9.20 esophagus:- stomach:9.78 intestine:9.88 colon:- liver/hepato:9.50 lung:9.73 bladder:9.74 kidney:9.65 pituitary:10.07 thyroid/parathyroid:- adrenal gland:9.91 pancreas:9.64 breast:9.55 salivary:9.51
CAGE uterus:4.34 placenta:4.15 prostate:4.07 ovary:4.28 testis:3.83 heart:- muscle:- esophagus:- stomach:3.87 intestine:4.41 colon:4.20     liver/hepato:3.70    lung:4.11 bladder:4.08 kidney:- pituitary:4.24 thyroid/parathyroid:- adrenal gland:4.08 pancreas:4.11 breast:4.12 salivary:-
RNA-seq uterus:- placenta:- prostate:- ovary:- testis:- heart:- muscle:8.90 esophagus:- stomach:- intestine:- colon:-     liver/hepato:9.79        lung:-    bladder:- kidney:- pituitary:- thyroid/parathyroid:- adrenal gland:- pancreas:- breast:- salivary:-

Gene Information

IDs

Refseq ID NM_133671
Gene ID 22185
Unigene ID Mm.360389
Probe set ID 1417260_at  [Mouse430_2]
Ensembl ID ENSMUSG00000030435

Orthologous Gene

Human[4]  NM_001012478, NM_007279
Rat[4]  NM_001012478, NM_007279

Chromosomal Region

-

Gene Family (Interpro ID)

IPR000504  RNA recognition motif, RNP-1

Link to Pubmed  (Pubmed ID)

1538748
1594454
8798720
9784496
10349636
11042159
11076861
11217851
12466851
12477932
12520002
12904583
14610273
16033648
16141072
16141073
17967808
18799693
19540372
21267068
21300889
21677750
21725067
21835928
21984414
22937132
24457600

Gene Ontology  (GO ID)

Biological Process

GO:0006397  mRNA processing
GO:0048025  negative regulation of nuclear mRNA splicing, via spliceosome
GO:0008380  RNA splicing

Cellular Component

GO:0016607  nuclear speck
GO:0005634  nucleus
GO:0030529  ribonucleoprotein complex
GO:0005681  spliceosomal complex
GO:0019012  virion

Molecular Function

GO:0070742  C2H2 zinc finger domain binding
GO:0019899  enzyme binding
GO:0003676  nucleic acid binding
GO:0000166  nucleotide binding
GO:0005515  protein binding
GO:0003723  RNA binding