FERM, RhoGEF (Arhgef) and pleckstrin domain protein 1 (chondrocyte-derived)

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Synonym

AW228844, Farp1, Cdep, BC030329

Expression Pattern

Choropleth map on BodyParts3D

Choropleth maps on 3D human body images were generated by the relative gene expression values measured by GeneChip.

Classification in 40 Organs

brain blood connective
EST nodata
GeneChip cerebrum:8.45 cerebellum:8.43 brain stem:- corpus callosum/glia:- pineal gland:- peripheral nerve:7.30 spine:8.53 retina:7.51 eye:7.81 artery/aorta:- vein:9.25 lymphnode:6.45 peripheral blood:- spleen:6.45 thymus:- bone marrow:5.50 adipose:7.96 bone:6.36 skin:7.05
CAGE cerebrum:4.04 cerebellum:- brain stem:4.08 corpus callosum/glia:- pineal gland:- peripheral nerve:- spine:3.90 retina:- eye:- artery/aorta:3.22 vein:- lymphnode:3.10 peripheral blood:- spleen:1.56 thymus:2.22 bone marrow:- adipose:- bone:2.37 skin:4.46
RNA-seq cerebrum:8.49 cerebellum:- brain stem:- corpus callosum/glia:- pineal gland:- peripheral nerve:- spine:- retina:- eye:- artery/aorta:- vein:- lymphnode:- peripheral blood:- spleen:- thymus:- bone marrow:- adipose:- bone:- skin:-
reproductive muscular alimentary liver lung urinary endo/exo-crine
EST nodata
GeneChip uterus:9.40 placenta:8.02 prostate:8.78 ovary:8.67 testis:5.72 heart:7.11 muscle:6.90 esophagus:- stomach:7.90 intestine:8.14 colon:- liver/hepato:7.87 lung:9.83 bladder:9.22 kidney:8.44 pituitary:9.33 thyroid/parathyroid:- adrenal gland:7.43 pancreas:8.01 breast:8.15 salivary:8.08
CAGE uterus:4.38 placenta:3.55 prostate:3.59 ovary:3.70 testis:0.45 heart:- muscle:- esophagus:- stomach:2.95 intestine:3.54 colon:3.53     liver/hepato:3.17    lung:4.42 bladder:4.37 kidney:- pituitary:4.61 thyroid/parathyroid:- adrenal gland:2.98 pancreas:4.50 breast:3.90 salivary:-
RNA-seq uterus:- placenta:- prostate:- ovary:- testis:- heart:- muscle:1.39 esophagus:- stomach:- intestine:- colon:-     liver/hepato:3.02        lung:-    bladder:- kidney:- pituitary:- thyroid/parathyroid:- adrenal gland:- pancreas:- breast:- salivary:-

Gene Information

IDs

Refseq ID NM_134082
Gene ID 223254
Unigene ID -
Probe set ID 1452280_at  [Mouse430_2]
Ensembl ID ENSMUSG00000025555

Orthologous Gene

Human[3]  NM_001001715, NM_005766
Rat[1]  NM_001107287, NM_005766

Chromosomal Region

-

Gene Family (Interpro ID)

IPR019749  Band 4.1 domain
IPR019750  Band 4.1 subgroup
IPR000798  Ezrin/radixin/moesin ERM
IPR001849  Pleckstrin homology

Link to Pubmed  (Pubmed ID)

7671812
8889548
10349636
10922068
11042159
11076861
11217851
11544199
12466851
12477932
14610273
14691545
15782199
16141072
16141073
16602821
17015433
21267068
23209303

Gene Ontology  (GO ID)

Biological Process

GO:0048813  dendrite morphogenesis
GO:0007275  multicellular organismal development
GO:0010923  negative regulation of phosphatase activity
GO:0035023  regulation of Rho protein signal transduction
GO:0007416  synapse assembly

Cellular Component

GO:0030054  cell junction
GO:0042995  cell projection
GO:0005737  cytoplasm
GO:0005856  cytoskeleton
GO:0005829  cytosol
GO:0030425  dendrite
GO:0031234  extrinsic to internal side of plasma membrane
GO:0019898  extrinsic to membrane
GO:0016020  membrane
GO:0043005  neuron projection
GO:0005886  plasma membrane
GO:0045202  synapse

Molecular Function

GO:0008092  cytoskeletal protein binding
GO:0005085  guanyl-nucleotide exchange factor activity
GO:0005543  phospholipid binding
GO:0048365  Rac GTPase binding
GO:0030676  Rac guanyl-nucleotide exchange factor activity
GO:0005089  Rho guanyl-nucleotide exchange factor activity