F-box and leucine-rich repeat protein 5

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Synonym

F-box/LRR-repeat protein 5, F-box and leucine-rich repeat protein 5, Fbxl5, Fir4, Fbl4

Expression Pattern

Choropleth map on BodyParts3D

Choropleth maps on 3D human body images were generated by the relative gene expression values measured by GeneChip.

Classification in 40 Organs

brain blood connective
EST cerebrum:137.20 cerebellum:257.90 brain stem:699.10 corpus callosum/glia:- pineal gland:- peripheral nerve:382.20 spine:47.30 retina:160.70 eye:114 artery/aorta:337.60 vein:- lymphnode:205.20 peripheral blood:43.10 spleen:131.70 thymus:266.80 bone marrow:115.40 adipose:- bone:150.30 skin:126.70
GeneChip nodata
CAGE cerebrum:3.89 cerebellum:- brain stem:3.65 corpus callosum/glia:- pineal gland:- peripheral nerve:- spine:3.80 retina:- eye:- artery/aorta:3.15 vein:- lymphnode:3.58 peripheral blood:- spleen:2.79 thymus:3.07 bone marrow:- adipose:- bone:3.21 skin:3.54
RNA-seq cerebrum:6.07 cerebellum:- brain stem:- corpus callosum/glia:- pineal gland:- peripheral nerve:- spine:- retina:- eye:- artery/aorta:- vein:- lymphnode:- peripheral blood:- spleen:- thymus:- bone marrow:- adipose:- bone:- skin:-
reproductive muscular alimentary liver lung urinary endo/exo-crine
EST uterus:130.90 placenta:207.10 prostate:30.90 ovary:172.40 testis:177.40 heart:130.20 muscle:106.50 esophagus:- stomach:130.90 intestine:- colon:70.50     liver/hepato:81.50        lung:180.80    bladder:264.70 kidney:48.40 pituitary:310 thyroid/parathyroid:- adrenal gland:424.40 pancreas:46.90 breast:78.40 salivary:-
GeneChip nodata
CAGE uterus:3.48 placenta:3.75 prostate:3.71 ovary:3.42 testis:4.22 heart:- muscle:- esophagus:- stomach:2.85 intestine:4.39 colon:4.05     liver/hepato:3.30    lung:3.73 bladder:3.21 kidney:- pituitary:3.66 thyroid/parathyroid:- adrenal gland:3.43 pancreas:2.56 breast:2.17 salivary:-
RNA-seq uterus:- placenta:- prostate:- ovary:- testis:- heart:- muscle:5.31 esophagus:- stomach:- intestine:- colon:-     liver/hepato:5.54        lung:-    bladder:- kidney:- pituitary:- thyroid/parathyroid:- adrenal gland:- pancreas:- breast:- salivary:-

Gene Information

IDs

Refseq ID NM_001159963
Gene ID 242960
Unigene ID Mm.25794
Probe set ID -
Ensembl ID ENSMUSG00000039753

Orthologous Gene

Human[2]  NM_001193534, NM_001193535, NM_012161
Rat[1]  NM_001107222, NM_001193535, NM_012161

Chromosomal Region

5B3  [44,135,855  -  44,212,878]

Gene Family (Interpro ID)

-

Link to Pubmed  (Pubmed ID)

8889548
10349636
10922068
11042159
11076861
11217851
11597144
12466851
12477932
14610273
15489334
15520277
15782199
16024820
16141072
16141073
16602821
18799693
21118569
21731673
21907140
23135277

Gene Ontology  (GO ID)

Biological Process

GO:0055072  iron ion homeostasis
GO:0016567  protein ubiquitination
GO:0031146  SCF-dependent proteasomal ubiquitin-dependent protein catabolic process

Cellular Component

GO:0005737  cytoplasm
GO:0048471  perinuclear region of cytoplasm
GO:0019005  SCF ubiquitin ligase complex

Molecular Function

GO:0005506  iron ion binding
GO:0046872  metal ion binding