protein kinase N1

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Synonym

F730027O18Rik, protein kinase N1, Prkcl1, Prk1, Pkn, Protein kinase C-like 1, DBK, Protein-kinase C-related kinase 1, Pkn1, PAK1, PRK1, Serine-threonine protein kinase N, Serine/threonine-protein kinase N1, Stk3, Protein kinase C-like PKN

Expression Pattern

Choropleth map on BodyParts3D

Choropleth maps on 3D human body images were generated by the relative gene expression values measured by GeneChip.

Classification in 40 Organs

brain blood connective
EST nodata
GeneChip cerebrum:5.36 cerebellum:5.74 brain stem:- corpus callosum/glia:- pineal gland:- peripheral nerve:5.69 spine:5.48 retina:5.20 eye:5.68 artery/aorta:- vein:5.65 lymphnode:7.80 peripheral blood:- spleen:7.71 thymus:- bone marrow:7.17 adipose:7 bone:6.73 skin:4.74
CAGE cerebrum:3.16 cerebellum:- brain stem:3.10 corpus callosum/glia:- pineal gland:- peripheral nerve:- spine:3.11 retina:- eye:- artery/aorta:4.09 vein:- lymphnode:4.23 peripheral blood:- spleen:3.79 thymus:4.34 bone marrow:- adipose:- bone:3.87 skin:3.07
RNA-seq cerebrum:5.32 cerebellum:- brain stem:- corpus callosum/glia:- pineal gland:- peripheral nerve:- spine:- retina:- eye:- artery/aorta:- vein:- lymphnode:- peripheral blood:- spleen:- thymus:- bone marrow:- adipose:- bone:- skin:-
reproductive muscular alimentary liver lung urinary endo/exo-crine
EST nodata
GeneChip uterus:6.29 placenta:6.26 prostate:6.60 ovary:6.18 testis:4.98 heart:6.09 muscle:6.07 esophagus:- stomach:6.57 intestine:7.05 colon:- liver/hepato:5.86 lung:6.60 bladder:5.84 kidney:6.55 pituitary:5.68 thyroid/parathyroid:- adrenal gland:6.68 pancreas:6.96 breast:6.35 salivary:6.92
CAGE uterus:3.44 placenta:3.21 prostate:3.68 ovary:3.39 testis:2.64 heart:- muscle:- esophagus:- stomach:3.62 intestine:3.51 colon:3.98     liver/hepato:2.90    lung:4.02 bladder:3.47 kidney:- pituitary:3.56 thyroid/parathyroid:- adrenal gland:3.92 pancreas:3.80 breast:3.74 salivary:-
RNA-seq uterus:- placenta:- prostate:- ovary:- testis:- heart:- muscle:5.60 esophagus:- stomach:- intestine:- colon:-     liver/hepato:5.54        lung:-    bladder:- kidney:- pituitary:- thyroid/parathyroid:- adrenal gland:- pancreas:- breast:- salivary:-

Gene Information

IDs

Refseq ID NM_177262
Gene ID 320795
Unigene ID -
Probe set ID 1436851_at  [Mouse430_2]
Ensembl ID ENSMUSG00000057672

Orthologous Gene

Human[2]  NM_002741, NM_213560
Rat [0]  

Chromosomal Region

-

Gene Family (Interpro ID)

IPR000961  AGC-kinase, C-terminal
IPR011072  HR1 rho-binding repeat
IPR000861  HR1-like rho-binding repeat
IPR000719  Protein kinase, catalytic domain
IPR011009  Protein kinase-like domain
IPR002290  Serine/threonine-protein kinase domain
IPR017442  Serine/threonine-protein kinase-like domain
IPR001245  Tyrosine-protein kinase, catalytic domain
IPR020635  Tyrosine-protein kinase, subgroup, catalytic domain

Link to Pubmed  (Pubmed ID)

8858105
8889548
9570957
10349636
11042159
11054541
11076861
11217851
12466851
12477932
12783890
15345747
15489334
15782199
16141072
16141073
18435913
18799693
19851504
20595653
21267068
21677750
23223530

Gene Ontology  (GO ID)

Biological Process

GO:0016568  chromatin modification
GO:0010631  epithelial cell migration
GO:0006972  hyperosmotic response
GO:0016310  phosphorylation
GO:0006468  protein amino acid phosphorylation
GO:0006357  regulation of transcription from RNA polymerase II promoter
GO:0006355  regulation of transcription, DNA-dependent
GO:0007165  signal transduction
GO:0006351  transcription, DNA-dependent

Cellular Component

GO:0032154  cleavage furrow
GO:0005737  cytoplasm
GO:0016023  cytoplasmic membrane-bounded vesicle
GO:0005768  endosome
GO:0016020  membrane
GO:0030496  midbody
GO:0005634  nucleus
GO:0005886  plasma membrane

Molecular Function

GO:0050681  androgen receptor binding
GO:0005524  ATP binding
GO:0003682  chromatin binding
GO:0017049  GTP-Rho binding
GO:0042393  histone binding
GO:0042826  histone deacetylase binding
GO:0016301  kinase activity
GO:0030374  ligand-dependent nuclear receptor transcription coactivator activity
GO:0000166  nucleotide binding
GO:0004672  protein kinase activity
GO:0004697  protein kinase C activity
GO:0005080  protein kinase C binding
GO:0004674  protein serine/threonine kinase activity
GO:0048365  Rac GTPase binding
GO:0016740  transferase activity
GO:0016772  transferase activity, transferring phosphorus-containing groups