CCR4-NOT transcription complex, subunit 4

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Synonym

Potential transcriptional repressor NOT4Hp, Not4, Not4hp, Cnot4, CCR4-associated factor 4, CCR4-NOT transcription complex subunit 4, Not4h, E3 ubiquitin protein ligase CNOT4, CCR4-NOT transcription complex, subunit 4

Expression Pattern

Choropleth map on BodyParts3D

Choropleth maps on 3D human body images were generated by the relative gene expression values measured by GeneChip.

Classification in 40 Organs

brain blood connective
EST cerebrum:- cerebellum:- brain stem:- corpus callosum/glia:- pineal gland:- peripheral nerve:- spine:- retina:- eye:- artery/aorta:- vein:- lymphnode:- peripheral blood:- spleen:- thymus:- bone marrow:- adipose:- bone:- skin:-
GeneChip cerebrum:8.36 cerebellum:8.51 brain stem:- corpus callosum/glia:- pineal gland:- peripheral nerve:8.30 spine:8.22 retina:7.55 eye:7.93 artery/aorta:- vein:8.19 lymphnode:8.11 peripheral blood:- spleen:8.29 thymus:- bone marrow:8.01 adipose:8.11 bone:8.20 skin:8.52
CAGE cerebrum:4.47 cerebellum:- brain stem:4.14 corpus callosum/glia:- pineal gland:- peripheral nerve:- spine:4.25 retina:- eye:- artery/aorta:4.41 vein:- lymphnode:5.66 peripheral blood:- spleen:4.26 thymus:4.53 bone marrow:- adipose:- bone:3.99 skin:4.79
RNA-seq cerebrum:3.52 cerebellum:- brain stem:- corpus callosum/glia:- pineal gland:- peripheral nerve:- spine:- retina:- eye:- artery/aorta:- vein:- lymphnode:- peripheral blood:- spleen:- thymus:- bone marrow:- adipose:- bone:- skin:-
reproductive muscular alimentary liver lung urinary endo/exo-crine
EST uterus:- placenta:- prostate:- ovary:- testis:- heart:- muscle:- esophagus:- stomach:- intestine:- colon:-     liver/hepato:-        lung:-    bladder:- kidney:- pituitary:- thyroid/parathyroid:- adrenal gland:- pancreas:- breast:- salivary:-
GeneChip uterus:7.51 placenta:7.76 prostate:7.49 ovary:8.16 testis:8.85 heart:8.29 muscle:8.69 esophagus:- stomach:7.43 intestine:7.78 colon:- liver/hepato:7.74 lung:8.15 bladder:8.12 kidney:7.85 pituitary:8.24 thyroid/parathyroid:- adrenal gland:8.30 pancreas:7.96 breast:8.27 salivary:8.03
CAGE uterus:4.14 placenta:3.80 prostate:3.86 ovary:4.19 testis:5.47 heart:- muscle:- esophagus:- stomach:3.21 intestine:3.62 colon:3.92     liver/hepato:3.78    lung:4.37 bladder:4.12 kidney:- pituitary:4.03 thyroid/parathyroid:- adrenal gland:4.01 pancreas:3.89 breast:3.69 salivary:-
RNA-seq uterus:- placenta:- prostate:- ovary:- testis:- heart:- muscle:2.50 esophagus:- stomach:- intestine:- colon:-     liver/hepato:1.89        lung:-    bladder:- kidney:- pituitary:- thyroid/parathyroid:- adrenal gland:- pancreas:- breast:- salivary:-

Gene Information

IDs

Refseq ID NM_001164412
Gene ID 53621
Unigene ID Mm.398182
Probe set ID 1450083_at  [Mouse430_2]
Ensembl ID ENSMUSG00000038784

Orthologous Gene

Human[6]  NM_001008225, NM_001190847, NM_001190848, NM_001190849, NM_001190850, NM_013316
Rat[1]  NM_001037782, NM_001190847, NM_001190848, NM_001190849, NM_001190850, NM_013316

Chromosomal Region

6B1  [34,972,066  -  35,083,737]

Gene Family (Interpro ID)

IPR000504  RNA recognition motif, RNP-1
IPR003954  RNA recognition, domain 1

Link to Pubmed  (Pubmed ID)

8889548
10349636
11042159
11076861
11217851
11389549
12466851
12477932
12520002
12904583
14610273
14681479
15226823
15489334
15618518
15782199
16033648
16141072
16141073
18287559
18799693
20059953
21677750

Gene Ontology  (GO ID)

Biological Process

GO:0051865  protein autoubiquitination
GO:0006355  regulation of transcription, DNA-dependent
GO:0006351  transcription, DNA-dependent

Cellular Component

GO:0030014  CCR4-NOT complex
GO:0005737  cytoplasm
GO:0005634  nucleus

Molecular Function

GO:0016874  ligase activity
GO:0046872  metal ion binding
GO:0003676  nucleic acid binding
GO:0000166  nucleotide binding
GO:0003723  RNA binding
GO:0004842  ubiquitin-protein ligase activity
GO:0008270  zinc ion binding