hydroxysteroid (17-beta) dehydrogenase 12

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Synonym

Hsd17b12, KAR, hydroxysteroid (17-beta) dehydrogenase 12, 17-beta-hydroxysteroid dehydrogenase 12, KIK-I, Kik1, Estradiol 17-beta-dehydrogenase 12, 2610510O05Rik, 17-beta-HSD 12, AI172963, 3-ketoacyl-CoA reductase

Expression Pattern

Choropleth map on BodyParts3D

Choropleth maps on 3D human body images were generated by the relative gene expression values measured by GeneChip.

Classification in 40 Organs

brain blood connective
EST cerebrum:39.90 cerebellum:- brain stem:31.80 corpus callosum/glia:- pineal gland:- peripheral nerve:57.30 spine:- retina:- eye:22.80 artery/aorta:- vein:- lymphnode:- peripheral blood:- spleen:- thymus:- bone marrow:- adipose:- bone:12.50 skin:63.30
GeneChip cerebrum:9.87 cerebellum:9.82 brain stem:- corpus callosum/glia:- pineal gland:- peripheral nerve:10.49 spine:10.54 retina:10.42 eye:10.20 artery/aorta:- vein:9.71 lymphnode:10.14 peripheral blood:- spleen:9.31 thymus:- bone marrow:9.25 adipose:11.42 bone:8.99 skin:11.82
CAGE cerebrum:3.93 cerebellum:- brain stem:4.27 corpus callosum/glia:- pineal gland:- peripheral nerve:- spine:4.29 retina:- eye:- artery/aorta:5.58 vein:- lymphnode:4.16 peripheral blood:- spleen:3.57 thymus:3.72 bone marrow:- adipose:- bone:3.89 skin:5.09
RNA-seq cerebrum:26.56 cerebellum:- brain stem:- corpus callosum/glia:- pineal gland:- peripheral nerve:- spine:- retina:- eye:- artery/aorta:- vein:- lymphnode:- peripheral blood:- spleen:- thymus:- bone marrow:- adipose:- bone:- skin:-
reproductive muscular alimentary liver lung urinary endo/exo-crine
EST uterus:- placenta:- prostate:- ovary:23 testis:- heart:- muscle:- esophagus:- stomach:- intestine:- colon:-     liver/hepato:-        lung:10    bladder:- kidney:24.20 pituitary:- thyroid/parathyroid:- adrenal gland:- pancreas:9.40 breast:35.90 salivary:-
GeneChip uterus:9.85 placenta:10.35 prostate:9.89 ovary:10.55 testis:8.07 heart:8.62 muscle:8.80 esophagus:- stomach:10.78 intestine:10.80 colon:- liver/hepato:11.92 lung:10.11 bladder:10.26 kidney:10.27 pituitary:9.89 thyroid/parathyroid:- adrenal gland:11.37 pancreas:8.53 breast:10.72 salivary:9.40
CAGE uterus:4.23 placenta:4.35 prostate:3.71 ovary:4.15 testis:2.71 heart:- muscle:- esophagus:- stomach:4.96 intestine:5.20 colon:4.65     liver/hepato:5.40    lung:4.07 bladder:4.41 kidney:- pituitary:3.54 thyroid/parathyroid:- adrenal gland:4.76 pancreas:3.89 breast:5.47 salivary:-
RNA-seq uterus:- placenta:- prostate:- ovary:- testis:- heart:- muscle:2.99 esophagus:- stomach:- intestine:- colon:-     liver/hepato:27.94        lung:-    bladder:- kidney:- pituitary:- thyroid/parathyroid:- adrenal gland:- pancreas:- breast:- salivary:-

Gene Information

IDs

Refseq ID NM_019657
Gene ID 56348
Unigene ID Mm.225050
Probe set ID 1450011_at  [Mouse430_2]
Ensembl ID ENSMUSG00000027195

Orthologous Gene

Human[1]  NM_016142
Rat [0]  

Chromosomal Region

-

Gene Family (Interpro ID)

IPR002347  Glucose/ribitol dehydrogenase
IPR002198  Short-chain dehydrogenase/reductase SDR

Link to Pubmed  (Pubmed ID)

10349636
10512203
10922068
11042159
11076861
11217851
11239426
12466851
12477932
12482854
12520002
12904583
14610273
14627762
14651920
14681479
15489334
15728386
15741177
15782199
15840001
16141072
16141073
17641292
18757743
18799693
20130115
21267068
21677750
23649778
24457600

Gene Ontology  (GO ID)

Biological Process

GO:0030198  extracellular matrix organization
GO:0006629  lipid metabolic process
GO:0008152  metabolic process
GO:0055114  oxidation reduction
GO:0010811  positive regulation of cell-substrate adhesion
GO:0006694  steroid biosynthetic process

Cellular Component

GO:0005783  endoplasmic reticulum
GO:0031012  extracellular matrix
GO:0016021  integral to membrane
GO:0016020  membrane

Molecular Function

GO:0005518  collagen binding
GO:0004303  estradiol 17-beta-dehydrogenase activity
GO:0001968  fibronectin binding
GO:0008201  heparin binding
GO:0016491  oxidoreductase activity