phosphoribosylaminoimidazole carboxylase, phosphoribosylaminoribosylaminoimidazole, succinocarboxamide synthetase

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Synonym

2610511I09Rik, PAIS, Paics, Multifunctional protein ADE2, AIRC, ADE2H1

Expression Pattern

Choropleth map on BodyParts3D

Choropleth maps on 3D human body images were generated by the relative gene expression values measured by GeneChip.

Classification in 40 Organs

brain blood connective
EST cerebrum:135.50 cerebellum:18.40 brain stem:- corpus callosum/glia:- pineal gland:- peripheral nerve:133.80 spine:- retina:482.20 eye:319.10 artery/aorta:- vein:- lymphnode:43.20 peripheral blood:287.50 spleen:26.30 thymus:39.50 bone marrow:76.90 adipose:425.40 bone:137.80 skin:87.10
GeneChip cerebrum:10.50 cerebellum:10.68 brain stem:- corpus callosum/glia:- pineal gland:- peripheral nerve:10.87 spine:10.73 retina:10.46 eye:11.41 artery/aorta:- vein:11.17 lymphnode:11.02 peripheral blood:- spleen:10.75 thymus:- bone marrow:11.69 adipose:11.22 bone:11.42 skin:10.78
CAGE cerebrum:4.40 cerebellum:- brain stem:4.49 corpus callosum/glia:- pineal gland:- peripheral nerve:- spine:4.52 retina:- eye:- artery/aorta:5.30 vein:- lymphnode:4.78 peripheral blood:- spleen:4.72 thymus:4.59 bone marrow:- adipose:- bone:4.34 skin:4.06
RNA-seq cerebrum:16.74 cerebellum:- brain stem:- corpus callosum/glia:- pineal gland:- peripheral nerve:- spine:- retina:- eye:- artery/aorta:- vein:- lymphnode:- peripheral blood:- spleen:- thymus:- bone marrow:- adipose:- bone:- skin:-
reproductive muscular alimentary liver lung urinary endo/exo-crine
EST uterus:218.10 placenta:345.20 prostate:92.60 ovary:160.90 testis:125.60 heart:93 muscle:142 esophagus:- stomach:163.60 intestine:37 colon:70.50     liver/hepato:153.90        lung:231    bladder:66.20 kidney:274 pituitary:64.60 thyroid/parathyroid:674.80 adrenal gland:- pancreas:150.10 breast:320 salivary:54
GeneChip uterus:11.22 placenta:10.50 prostate:11.51 ovary:11.49 testis:9.55 heart:11.28 muscle:11.54 esophagus:- stomach:10.66 intestine:9.98 colon:- liver/hepato:11.93 lung:11.18 bladder:10.88 kidney:12.04 pituitary:10.53 thyroid/parathyroid:- adrenal gland:10.71 pancreas:11.31 breast:11.25 salivary:10.57
CAGE uterus:4.52 placenta:4.34 prostate:4.22 ovary:4.68 testis:3.63 heart:- muscle:- esophagus:- stomach:4.53 intestine:3.13 colon:3.57     liver/hepato:5.64    lung:4.73 bladder:4.53 kidney:- pituitary:4.31 thyroid/parathyroid:- adrenal gland:4.80 pancreas:4.66 breast:4.62 salivary:-
RNA-seq uterus:- placenta:- prostate:- ovary:- testis:- heart:- muscle:14.38 esophagus:- stomach:- intestine:- colon:-     liver/hepato:40.56        lung:-    bladder:- kidney:- pituitary:- thyroid/parathyroid:- adrenal gland:- pancreas:- breast:- salivary:-

Gene Information

IDs

Refseq ID NM_025939
Gene ID 67054
Unigene ID Mm.182931
Probe set ID 1423565_at  [Mouse430_2]
Ensembl ID ENSMUSG00000029247

Orthologous Gene

Human[18]  NM_001079524, NM_001079525, NM_006452
Rat [0]  

Chromosomal Region

-

Gene Family (Interpro ID)

-

Link to Pubmed  (Pubmed ID)

10349636
10922068
11042159
11076861
11217851
11544199
12466851
12477932
12520002
12904583
14610273
14681479
15604097
15782199
16141072
16141073
16512683
18287559
18554416
18799693
19334288
21267068
22922362
24457600

Gene Ontology  (GO ID)

Biological Process

GO:0006189  'de novo' IMP biosynthetic process
GO:0008152  metabolic process
GO:0006164  purine nucleotide biosynthetic process

Cellular Component

GO:0005575  cellular_component

Molecular Function

GO:0034023  5-(carboxyamino)imidazole ribonucleotide mutase activity
GO:0005524  ATP binding
GO:0016831  carboxy-lyase activity
GO:0003824  catalytic activity
GO:0042802  identical protein binding
GO:0016874  ligase activity
GO:0016829  lyase activity
GO:0000166  nucleotide binding
GO:0004638  phosphoribosylaminoimidazole carboxylase activity
GO:0004639  phosphoribosylaminoimidazolesuccinocarboxamide synthase activity