PRP6 pre-mRNA splicing factor 6 homolog (yeast)

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Synonym

Prpf6, 2610031L17Rik, 1190003A07Rik, ANT-1, U5 snRNP-associated 102 kDa protein, MGC11655, U5-102K, U5-102 kDa protein, PRP6 pre-mRNA splicing factor 6 homolog (yeast), MGC36967, MGC38351, Pre-mRNA-processing factor 6 homolog

Expression Pattern

Choropleth map on BodyParts3D

Choropleth maps on 3D human body images were generated by the relative gene expression values measured by GeneChip.

Classification in 40 Organs

brain blood connective
EST cerebrum:118.10 cerebellum:55.30 brain stem:31.80 corpus callosum/glia:- pineal gland:- peripheral nerve:- spine:94.60 retina:64.30 eye:197.60 artery/aorta:- vein:- lymphnode:- peripheral blood:115 spleen:26.30 thymus:128.40 bone marrow:38.50 adipose:212.70 bone:- skin:118.80
GeneChip cerebrum:8.52 cerebellum:8.76 brain stem:- corpus callosum/glia:- pineal gland:- peripheral nerve:8.54 spine:8.31 retina:8.96 eye:8.69 artery/aorta:- vein:8.50 lymphnode:8.93 peripheral blood:- spleen:8.80 thymus:- bone marrow:8.70 adipose:8.79 bone:8.38 skin:8.23
CAGE cerebrum:4.42 cerebellum:- brain stem:4.29 corpus callosum/glia:- pineal gland:- peripheral nerve:- spine:4.30 retina:- eye:- artery/aorta:4.44 vein:- lymphnode:4.90 peripheral blood:- spleen:4.22 thymus:4.44 bone marrow:- adipose:- bone:3.89 skin:4.41
RNA-seq cerebrum:10.04 cerebellum:- brain stem:- corpus callosum/glia:- pineal gland:- peripheral nerve:- spine:- retina:- eye:- artery/aorta:- vein:- lymphnode:- peripheral blood:- spleen:- thymus:- bone marrow:- adipose:- bone:- skin:-
reproductive muscular alimentary liver lung urinary endo/exo-crine
EST uterus:43.60 placenta:234.70 prostate:30.90 ovary:287.30 testis:206.90 heart:55.80 muscle:142 esophagus:- stomach:- intestine:- colon:17.60     liver/hepato:18.10        lung:110.50    bladder:- kidney:80.60 pituitary:155 thyroid/parathyroid:- adrenal gland:- pancreas:131.40 breast:75.10 salivary:-
GeneChip uterus:9.17 placenta:9.04 prostate:9.17 ovary:9.13 testis:8.58 heart:8.25 muscle:8.55 esophagus:- stomach:8.45 intestine:8.53 colon:- liver/hepato:9.33 lung:8.59 bladder:8.76 kidney:8.54 pituitary:9.19 thyroid/parathyroid:- adrenal gland:8.72 pancreas:8.41 breast:8.67 salivary:8.02
CAGE uterus:4.40 placenta:4.17 prostate:4.47 ovary:4.43 testis:4.97 heart:- muscle:- esophagus:- stomach:4.11 intestine:4.01 colon:4.04     liver/hepato:4.44    lung:4.23 bladder:4.37 kidney:- pituitary:4.63 thyroid/parathyroid:- adrenal gland:4.37 pancreas:3.89 breast:4.04 salivary:-
RNA-seq uterus:- placenta:- prostate:- ovary:- testis:- heart:- muscle:5.69 esophagus:- stomach:- intestine:- colon:-     liver/hepato:8.78        lung:-    bladder:- kidney:- pituitary:- thyroid/parathyroid:- adrenal gland:- pancreas:- breast:- salivary:-

Gene Information

IDs

Refseq ID NM_133701
Gene ID 68879
Unigene ID Mm.292001
Probe set ID 1424036_at  [Mouse430_2]
Ensembl ID ENSMUSG00000002455

Orthologous Gene

Human[2]  NM_012469
Rat[1]  NM_001079766

Chromosomal Region

-

Gene Family (Interpro ID)

IPR019734  Tetratricopeptide repeat

Link to Pubmed  (Pubmed ID)

10349636
10922068
11042159
11076861
11217851
12466851
12477932
12520002
14610273
15489334
15782199
16033648
16141072
16141073
16414017
18799693
22922362
24457600

Gene Ontology  (GO ID)

Biological Process

GO:0000244  assembly of spliceosomal tri-snRNP
GO:0006397  mRNA processing
GO:0000398  nuclear mRNA splicing, via spliceosome
GO:0045944  positive regulation of transcription from RNA polymerase II promoter
GO:0006403  RNA localization
GO:0006396  RNA processing
GO:0008380  RNA splicing

Cellular Component

GO:0071013  catalytic step 2 spliceosome
GO:0005622  intracellular
GO:0005634  nucleus
GO:0005681  spliceosomal complex
GO:0071001  U4/U6 snRNP
GO:0046540  U4/U6 x U5 tri-snRNP complex
GO:0005682  U5 snRNP

Molecular Function

GO:0050681  androgen receptor binding
GO:0043021  ribonucleoprotein binding
GO:0003723  RNA binding
GO:0003713  transcription coactivator activity