cytochrome P450, family 4, subfamily f, polypeptide 18

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Synonym

Cyp4f18, 1810054N16Rik, CYPIVF3, Cypf18, Cytochrome P450-LTB-omega, Cyp4f3, Leukotriene-B(4) 20-monooxygenase, Cytochrome P450 4F3, Leukotriene-B(4) omega-hydroxylase

Expression Pattern

Choropleth map on BodyParts3D

Choropleth maps on 3D human body images were generated by the relative gene expression values measured by GeneChip.

Classification in 40 Organs

brain blood connective
EST cerebrum:- cerebellum:- brain stem:- corpus callosum/glia:- pineal gland:- peripheral nerve:- spine:- retina:- eye:- artery/aorta:- vein:- lymphnode:54 peripheral blood:14.40 spleen:13.20 thymus:9.90 bone marrow:- adipose:- bone:25 skin:-
GeneChip cerebrum:4.62 cerebellum:4.86 brain stem:- corpus callosum/glia:- pineal gland:- peripheral nerve:4.63 spine:4.99 retina:4.80 eye:5.04 artery/aorta:- vein:4.71 lymphnode:9.36 peripheral blood:- spleen:10.19 thymus:- bone marrow:9.16 adipose:5.37 bone:9.10 skin:4.84
CAGE cerebrum:0 cerebellum:- brain stem:0 corpus callosum/glia:- pineal gland:- peripheral nerve:- spine:0 retina:- eye:- artery/aorta:0.14 vein:- lymphnode:2.20 peripheral blood:- spleen:1.69 thymus:0.49 bone marrow:- adipose:- bone:1.69 skin:0.15
RNA-seq cerebrum:2.32 cerebellum:- brain stem:- corpus callosum/glia:- pineal gland:- peripheral nerve:- spine:- retina:- eye:- artery/aorta:- vein:- lymphnode:- peripheral blood:- spleen:- thymus:- bone marrow:- adipose:- bone:- skin:-
reproductive muscular alimentary liver lung urinary endo/exo-crine
EST uterus:- placenta:- prostate:- ovary:- testis:- heart:- muscle:- esophagus:- stomach:- intestine:- colon:17.60     liver/hepato:-        lung:10    bladder:66.20 kidney:- pituitary:- thyroid/parathyroid:- adrenal gland:- pancreas:9.40 breast:22.90 salivary:-
GeneChip uterus:6.47 placenta:5.70 prostate:5.11 ovary:5.42 testis:4.65 heart:5.25 muscle:5.46 esophagus:- stomach:5.21 intestine:5.62 colon:- liver/hepato:4.89 lung:6.19 bladder:4.86 kidney:4.91 pituitary:5.06 thyroid/parathyroid:- adrenal gland:5.42 pancreas:5.63 breast:5.85 salivary:5.22
CAGE uterus:0.97 placenta:0.10 prostate:0.51 ovary:0.45 testis:0 heart:- muscle:- esophagus:- stomach:0 intestine:0 colon:0.70     liver/hepato:0    lung:1.42 bladder:0.46 kidney:- pituitary:0.52 thyroid/parathyroid:- adrenal gland:0.64 pancreas:0 breast:0.32 salivary:-
RNA-seq uterus:- placenta:- prostate:- ovary:- testis:- heart:- muscle:1.67 esophagus:- stomach:- intestine:- colon:-     liver/hepato:19.06        lung:-    bladder:- kidney:- pituitary:- thyroid/parathyroid:- adrenal gland:- pancreas:- breast:- salivary:-

Gene Information

IDs

Refseq ID NM_024444
Gene ID 72054
Unigene ID Mm.160020
Probe set ID 1419219_at  [Mouse430_2]
Ensembl ID ENSMUSG00000003484

Orthologous Gene

Human [0]  
Rat [0]  

Chromosomal Region

-

Gene Family (Interpro ID)

IPR001128  Cytochrome P450
IPR002401  Cytochrome P450, E-class, group I
IPR002402  Cytochrome P450, E-class, group II
IPR002403  Cytochrome P450, E-class, group IV

Link to Pubmed  (Pubmed ID)

10349636
11042159
11076861
11217851
12466851
12477932
14681479
15489334
16141072
16141073
16380383
17081494
21267068
21677750
24632148

Gene Ontology  (GO ID)

Biological Process

GO:0019369  arachidonic acid metabolic process
GO:0017144  drug metabolic process
GO:0019373  epoxygenase P450 pathway
GO:0001676  long-chain fatty acid metabolic process
GO:0030195  negative regulation of blood coagulation
GO:0032304  negative regulation of icosanoid secretion
GO:0055114  oxidation reduction
GO:0032305  positive regulation of icosanoid secretion
GO:0008217  regulation of blood pressure
GO:0000038  very-long-chain fatty acid metabolic process
GO:0042360  vitamin E metabolic process
GO:0042371  vitamin K biosynthetic process

Cellular Component

GO:0016324  apical plasma membrane
GO:0005737  cytoplasm
GO:0005783  endoplasmic reticulum
GO:0016021  integral to membrane
GO:0043231  intracellular membrane-bounded organelle
GO:0016020  membrane

Molecular Function

GO:0018685  alkane 1-monooxygenase activity
GO:0008392  arachidonic acid epoxygenase activity
GO:0009055  electron carrier activity
GO:0020037  heme binding
GO:0005506  iron ion binding
GO:0050051  leukotriene-B4 20-monooxygenase activity
GO:0046872  metal ion binding
GO:0004497  monooxygenase activity
GO:0016491  oxidoreductase activity
GO:0016705  oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen
GO:0047057  vitamin-K-epoxide reductase (warfarin-sensitive) activity