synaptotagmin-like 2

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Synonym

Slp2-d, Slp2-a, Synaptotagmin-like protein 2, mKIAA1597, AI266830, Slp2, Slp2-c, synaptotagmin-like 2, Sytl2, Exophilin-4, KIAA1597, Slp2-b

Expression Pattern

Choropleth map on BodyParts3D

Choropleth maps on 3D human body images were generated by the relative gene expression values measured by GeneChip.

Classification in 40 Organs

brain blood connective
EST nodata
GeneChip cerebrum:7.83 cerebellum:6.67 brain stem:- corpus callosum/glia:- pineal gland:- peripheral nerve:10.06 spine:8.37 retina:8.11 eye:7.12 artery/aorta:- vein:7.60 lymphnode:5.96 peripheral blood:- spleen:5.67 thymus:- bone marrow:4.93 adipose:5.77 bone:6.48 skin:5.96
CAGE cerebrum:2.00 cerebellum:- brain stem:2.81 corpus callosum/glia:- pineal gland:- peripheral nerve:- spine:3.07 retina:- eye:- artery/aorta:0.25 vein:- lymphnode:0 peripheral blood:- spleen:0 thymus:0.49 bone marrow:- adipose:- bone:0 skin:0.51
RNA-seq cerebrum:3.78 cerebellum:- brain stem:- corpus callosum/glia:- pineal gland:- peripheral nerve:- spine:- retina:- eye:- artery/aorta:- vein:- lymphnode:- peripheral blood:- spleen:- thymus:- bone marrow:- adipose:- bone:- skin:-
reproductive muscular alimentary liver lung urinary endo/exo-crine
EST nodata
GeneChip uterus:7.13 placenta:5.98 prostate:5.10 ovary:7.07 testis:5.48 heart:6.19 muscle:6.91 esophagus:- stomach:9.85 intestine:8.53 colon:- liver/hepato:5.41 lung:7.25 bladder:9.58 kidney:7.12 pituitary:5.11 thyroid/parathyroid:- adrenal gland:5.99 pancreas:5.94 breast:5.36 salivary:5.06
CAGE uterus:0 placenta:0 prostate:0.37 ovary:0.54 testis:0.75 heart:- muscle:- esophagus:- stomach:0.67 intestine:0 colon:0     liver/hepato:0.64    lung:0.83 bladder:0.46 kidney:- pituitary:1.11 thyroid/parathyroid:- adrenal gland:0 pancreas:0 breast:0.20 salivary:-
RNA-seq uterus:- placenta:- prostate:- ovary:- testis:- heart:- muscle:2.15 esophagus:- stomach:- intestine:- colon:-     liver/hepato:1.68        lung:-    bladder:- kidney:- pituitary:- thyroid/parathyroid:- adrenal gland:- pancreas:- breast:- salivary:-

Gene Information

IDs

Refseq ID NM_001040085
Gene ID 83671
Unigene ID -
Probe set ID 1421594_a_at  [Mouse430_2]
Ensembl ID ENSMUSG00000030616

Orthologous Gene

Human[9]  NM_001162951, NM_001162952, NM_001162953, NM_032379, NM_032943, NM_206927, NM_206928, NM_206929, NM_206930
Rat[9]  NM_001162951, NM_001162952, NM_001162953, NM_032379, NM_032943, NM_206927, NM_206928, NM_206929, NM_206930

Chromosomal Region

-

Gene Family (Interpro ID)

IPR000008  C2 calcium-dependent membrane targeting
IPR008973  C2 calcium/lipid-binding domain, CaLB
IPR018029  C2 membrane targeting protein
IPR010911  Rab-binding domain
IPR011011  Zinc finger, FYVE/PHD-type
IPR013083  Zinc finger, RING/FYVE/PHD-type

Link to Pubmed  (Pubmed ID)

8889548
10349636
11042159
11076861
11217851
11243866
11327731
11773082
11980908
12466851
12477932
12590134
15368895
15543135
15782199
16141072
16141073
16376427
16716193
17015433
17114649
17182843
18266782
18607085
18940603
19208631
19360003
20729199
21267068
21677750
22767581

Gene Ontology  (GO ID)

Biological Process

GO:0006887  exocytosis
GO:0006886  intracellular protein transport
GO:0010923  negative regulation of phosphatase activity
GO:0070257  positive regulation of mucus secretion
GO:0006904  vesicle docking during exocytosis

Cellular Component

GO:0005737  cytoplasm
GO:0070382  exocytic vesicle
GO:0019897  extrinsic to plasma membrane
GO:0005794  Golgi apparatus
GO:0042470  melanosome
GO:0016020  membrane
GO:0005634  nucleus
GO:0005886  plasma membrane

Molecular Function

GO:0042043  neurexin binding
GO:0019902  phosphatase binding
GO:0005546  phosphatidylinositol-4,5-bisphosphate binding
GO:0001786  phosphatidylserine binding
GO:0005515  protein binding
GO:0017137  Rab GTPase binding