24-dehydrocholesterol reductase

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Synonym

-

Expression Pattern

Choropleth map on BodyParts3D

Choropleth maps on 3D human body images were generated by the relative gene expression values measured by GeneChip.

Classification in 40 Organs

brain blood connective
EST cerebrum:203.40 cerebellum:- brain stem:- corpus callosum/glia:- pineal gland:- peripheral nerve:368.70 spine:- retina:- eye:106.60 artery/aorta:- vein:- lymphnode:- peripheral blood:- spleen:234 thymus:- bone marrow:- adipose:- bone:39 skin:-
GeneChip nodata
CAGE nodata
RNA-seq nodata
reproductive muscular alimentary liver lung urinary endo/exo-crine
EST uterus:- placenta:- prostate:75.90 ovary:- testis:82.30 heart:96.90 muscle:- esophagus:- stomach:- intestine:418.70 colon:289.90     liver/hepato:186.20        lung:152    bladder:- kidney:127.60 pituitary:118.40 thyroid/parathyroid:- adrenal gland:- pancreas:56.90 breast:- salivary:-
GeneChip nodata
CAGE nodata
RNA-seq nodata

Gene Information

IDs

Refseq ID NM_001080148
Gene ID 298298
Unigene ID Rn.9470
Probe set ID -
Ensembl ID ENSRNOG00000006787

Orthologous Gene

Human[1]  NM_014762
Mouse[3]  NM_053272

Chromosomal Region

5q34  [127,637,376  -  127,662,621]

Gene Family (Interpro ID)

IPR006094  FAD linked oxidase, N-terminal
IPR016166  FAD-binding, type 2

Link to Pubmed  (Pubmed ID)

11519011
12668600
15577914
16876788
17210742
18468884
19520779

Gene Ontology  (GO ID)

Biological Process

GO:0042987  amyloid precursor protein catabolic process
GO:0006695  cholesterol biosynthetic process
GO:0008203  cholesterol metabolic process
GO:0030539  male genitalia development
GO:0016044  membrane organization
GO:0043066  negative regulation of apoptosis
GO:0043154  negative regulation of caspase activity
GO:0008285  negative regulation of cell proliferation
GO:0031639  plasminogen activation
GO:0008104  protein localization
GO:0007265  Ras protein signal transduction
GO:0009725  response to hormone stimulus
GO:0006979  response to oxidative stress
GO:0043588  skin development
GO:0008202  steroid metabolic process
GO:0016125  sterol metabolic process
GO:0009888  tissue development

Cellular Component

GO:0005737  cytoplasm
GO:0005856  cytoskeleton
GO:0005829  cytosol
GO:0005783  endoplasmic reticulum
GO:0005789  endoplasmic reticulum membrane
GO:0000139  Golgi membrane
GO:0016021  integral to membrane
GO:0016020  membrane
GO:0005634  nucleus

Molecular Function

GO:0050614  delta24-sterol reductase activity
GO:0019899  enzyme binding
GO:0050660  FAD binding
GO:0016491  oxidoreductase activity
GO:0016628  oxidoreductase activity, acting on the CH-CH group of donors, NAD or NADP as acceptor
GO:0042605  peptide antigen binding
GO:0008762  UDP-N-acetylmuramate dehydrogenase activity