v-akt murine thymoma viral oncogene homolog 3 (protein kinase B, gamma)

Synonym

PRKBG, PKB gamma, Akt-3, RAC-gamma serine/threonine-protein kinase, DKFZP434N0250, RAC-gamma, PKBG, Protein kinase B, gamma, Protein kinase Akt-3, AKT-3, RAC-PK-gamma, AKT 3, AKT3, Akt 3, STK-2

normal 40 tissues
cell lines, primary cells, adult tissues and fetal tissues (FANTOM5 CAGE)

Choropleth map on BodyParts3D

Choropleth maps on 3D human body images were generated by the relative gene expression values measured by GeneChip.

Classification in 40 Organs

brain

blood

connective

EST

cerebrum:174.20

cerebellum:125.90

brain stem:-

corpus callosum/glia:175

pineal gland:148.30

peripheral nerve:276

spine:112.30

retina:-

eye:235.10

artery/aorta:89.90

vein:66.60

lymphnode:80.90

peripheral blood:-

spleen:56.70

thymus:154.60

bone marrow:-

adipose:121

bone:102.40

skin:62.40

GeneChip

cerebrum:7.81

cerebellum:8.33

brain stem:7.42

corpus callosum/glia:7.70

pineal gland:-

peripheral nerve:7.70

spine:7.55

retina:-

eye:-

artery/aorta:7.61

vein:7.84

lymphnode:7.03

peripheral blood:-

spleen:7.11

thymus:6.42

bone marrow:5.61

adipose:7

bone:-

skin:6.94

CAGE

cerebrum:3.79

cerebellum:-

brain stem:3.82

corpus callosum/glia:3.65

pineal gland:3.83

peripheral nerve:-

spine:3.34

retina:-

eye:-

artery/aorta:3.71

vein:3.00

lymphnode:2.42

peripheral blood:-

spleen:2.55

thymus:2.26

bone marrow:-

adipose:3.45

bone:-

skin:-

RNA-seq

cerebrum:4.14

cerebellum:-

brain stem:-

corpus callosum/glia:-

pineal gland:-

peripheral nerve:-

spine:-

retina:-

eye:-

artery/aorta:-

vein:-

lymphnode:3.66

peripheral blood:-

spleen:-

thymus:-

bone marrow:-

adipose:4.28

bone:-

skin:-

reproductive

muscular

alimentary

liver

lung

urinary

endo/exo-crine

EST

uterus:164

placenta:58.30

prostate:112.60

ovary:149.10

testis:116.80

heart:114.90

muscle:40.20

esophagus:-

stomach:85

intestine:32.40

colon:42.40

liver/hepato:31.70

lung:63.50

bladder:-

kidney:31.20

pituitary:116

thyroid/parathyroid:163.70

adrenal gland:152.40

pancreas:249

breast:102.20

salivary:-

GeneChip

uterus:7.72

placenta:7.50

prostate:7.35

ovary:7.84

testis:6.72

heart:6.68

muscle:6.23

esophagus:6.45

stomach:6.74

intestine:6.47

colon:6.34

liver/hepato:5.86

lung:7.66

bladder:-

kidney:6.56

pituitary:7.25

thyroid/parathyroid:7.42

adrenal gland:7.28

pancreas:6

breast:7.18

salivary:5.63

CAGE

uterus:3.98

placenta:3.00

prostate:3.57

ovary:3.68

testis:3.20

heart:3.14

muscle:2.60

esophagus:3.24

stomach:-

intestine:2.30

colon:2.69

liver/hepato:1.63

lung:3.37

bladder:4.03

kidney:2.70

pituitary:3.30

thyroid/parathyroid:3.47

adrenal gland:-

pancreas:2.18

breast:3.30

salivary:1.49

RNA-seq

uterus:-

placenta:-

prostate:4.26

ovary:4.03

testis:3.70

heart:2.53

muscle:1.97

esophagus:-

stomach:-

intestine:-

colon:4.65

liver/hepato:1.45

lung:4.02

bladder:-

kidney:3.15

pituitary:-

thyroid/parathyroid:3.67

adrenal gland:2.89

pancreas:-

breast:3.17

salivary:-

IDs

Refseq ID	NM_005465
Gene ID	10000
Unigene ID	Hs.498292
Probe set ID	212609_s_at [HG-U133_Plus_2]
Ensembl ID	ENSG00000117020
GTEx ID	ENSG00000117020

Orthologous Gene

Mouse[2]	NM_011785
Rat[2]	NM_011785

Chromosomal Region

1q44 [243,651,535 - 244,014,381]

Search genes near this gene
- Between -5kb and +5kb
- Between -10kb and +10kb

Gene Family (Interpro ID)

IPR000961	AGC-kinase, C-terminal
IPR001849	Pleckstrin homology
IPR000719	Protein kinase, catalytic domain
IPR011009	Protein kinase-like domain
IPR002290	Serine/threonine-protein kinase domain
IPR017442	Serine/threonine-protein kinase-like domain
IPR001245	Tyrosine-protein kinase, catalytic domain
IPR020635	Tyrosine-protein kinase, subgroup, catalytic domain

Gene Ontology (GO ID)

Biological Process

GO:0000002	mitochondrial genome maintenance
GO:0006468	protein amino acid phosphorylation
GO:0007165	signal transduction

Cellular Component

GO:0005737	cytoplasm
GO:0005794	Golgi apparatus
GO:0005730	nucleolus
GO:0005634	nucleus
GO:0005886	plasma membrane

Molecular Function

GO:0005524	ATP binding
GO:0005543	phospholipid binding
GO:0005515	protein binding
GO:0004672	protein kinase activity
GO:0004674	protein serine/threonine kinase activity

v-akt murine thymoma viral oncogene homolog 3 (protein kinase B, gamma)

Synonym

Expression Pattern

Choropleth map on BodyParts3D

Classification in 40 Organs

Gene Information

IDs

Orthologous Gene

Chromosomal Region

Gene Family (Interpro ID)

Link to Pubmed (Pubmed ID)

Gene Ontology (GO ID)

Biological Process

Cellular Component

Molecular Function