programmed cell death 6

Synonym

PDCD6, programmed cell death 6, ALG-2, Probable calcium-binding protein ALG-2, MGC111017, ALG2, Programmed cell death protein 6, MGC9123, MGC119050, PEF1B

normal 40 tissues
cell lines, primary cells, adult tissues and fetal tissues (FANTOM5 CAGE)

Choropleth map on BodyParts3D

Choropleth maps on 3D human body images were generated by the relative gene expression values measured by GeneChip.

Classification in 40 Organs

brain

blood

connective

EST

nodata

GeneChip

cerebrum:7.33

cerebellum:7.42

brain stem:7.42

corpus callosum/glia:7.23

pineal gland:-

peripheral nerve:7.10

spine:7.29

retina:-

eye:-

artery/aorta:6.92

vein:6.57

lymphnode:7.22

peripheral blood:-

spleen:7.37

thymus:7.93

bone marrow:6.81

adipose:7.24

bone:-

skin:7.45

CAGE

cerebrum:4.16

cerebellum:-

brain stem:4.03

corpus callosum/glia:4.00

pineal gland:3.70

peripheral nerve:-

spine:4.14

retina:-

eye:-

artery/aorta:4.09

vein:4.17

lymphnode:4.23

peripheral blood:-

spleen:3.90

thymus:3.73

bone marrow:-

adipose:3.89

bone:-

skin:-

RNA-seq

cerebrum:5.18

cerebellum:-

brain stem:-

corpus callosum/glia:-

pineal gland:-

peripheral nerve:-

spine:-

retina:-

eye:-

artery/aorta:-

vein:-

lymphnode:5.24

peripheral blood:-

spleen:-

thymus:-

bone marrow:-

adipose:4.43

bone:-

skin:-

reproductive

muscular

alimentary

liver

lung

urinary

endo/exo-crine

EST

nodata

GeneChip

uterus:7.56

placenta:7.34

prostate:7.98

ovary:7.70

testis:7.46

heart:6.54

muscle:6.03

esophagus:8.10

stomach:7.20

intestine:7.27

colon:7.41

liver/hepato:6.66

lung:7.16

bladder:-

kidney:7.27

pituitary:7.34

thyroid/parathyroid:7.73

adrenal gland:7.49

pancreas:7.15

breast:7.37

salivary:7.33

CAGE

uterus:3.78

placenta:3.96

prostate:3.79

ovary:3.73

testis:3.86

heart:3.77

muscle:3.34

esophagus:3.97

stomach:-

intestine:4.24

colon:4.20

liver/hepato:3.93

lung:4.00

bladder:3.46

kidney:3.97

pituitary:4.17

thyroid/parathyroid:4.15

adrenal gland:-

pancreas:4.18

breast:4.07

salivary:4.28

RNA-seq

uterus:-

placenta:-

prostate:5.39

ovary:5.58

testis:5.63

heart:3.68

muscle:3.95

esophagus:-

stomach:-

intestine:-

colon:5.03

liver/hepato:4.92

lung:4.56

bladder:-

kidney:5.59

pituitary:-

thyroid/parathyroid:6.00

adrenal gland:5.52

pancreas:-

breast:5.46

salivary:-

IDs

Refseq ID	NM_013232
Gene ID	10016
Unigene ID	-
Probe set ID	203415_at [HG-U133_Plus_2]
Ensembl ID	ENSG00000249915
GTEx ID	ENSG00000249915

Orthologous Gene

Mouse[1]	NM_011051
Rat[1]	NM_001107452

Chromosomal Region

5p15.33 [271,736 - 353,971]

Search genes near this gene
- Between -5kb and +5kb
- Between -10kb and +10kb

Gene Family (Interpro ID)

IPR002048	Calcium-binding EF-hand
IPR018249	EF-HAND 2

Link to Pubmed (Pubmed ID)

Gene Ontology (GO ID)

Biological Process

GO:0006919	activation of caspase activity
GO:0033554	cellular response to stress
GO:0006886	intracellular protein transport
GO:0051898	negative regulation of protein kinase B signaling cascade
GO:0032007	negative regulation of TOR signaling pathway
GO:0030948	negative regulation of vascular endothelial growth factor receptor signaling pathway
GO:0045766	positive regulation of angiogenesis
GO:0010595	positive regulation of endothelial cell migration
GO:0001938	positive regulation of endothelial cell proliferation
GO:0051592	response to calcium ion

Cellular Component

GO:0005737	cytoplasm
GO:0031410	cytoplasmic vesicle
GO:0005783	endoplasmic reticulum
GO:0005789	endoplasmic reticulum membrane
GO:0031965	nuclear membrane
GO:0005634	nucleus

Molecular Function

GO:0005509	calcium ion binding
GO:0048306	calcium-dependent protein binding
GO:0060090	molecular adaptor activity
GO:0005515	protein binding
GO:0046983	protein dimerization activity
GO:0042803	protein homodimerization activity

programmed cell death 6

Synonym

Expression Pattern

Choropleth map on BodyParts3D

Classification in 40 Organs

Gene Information

IDs

Orthologous Gene

Chromosomal Region

Gene Family (Interpro ID)

Link to Pubmed (Pubmed ID)

Gene Ontology (GO ID)

Biological Process

Cellular Component

Molecular Function