Epstein-Barr virus induced 3

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Synonym

Epstein-Barr virus induced gene 3, Interleukin-27 beta chain precursor, IL-27B, EBV-induced gene 3 protein, IL27B, Epstein-Barr virus-induced gene 3 protein, EBI3

Expression Pattern

Choropleth map on BodyParts3D

Choropleth maps on 3D human body images were generated by the relative gene expression values measured by GeneChip.

Classification in 40 Organs

brain blood connective
EST cerebrum:- cerebellum:- brain stem:- corpus callosum/glia:- pineal gland:- peripheral nerve:- spine:- retina:- eye:17.60 artery/aorta:- vein:- lymphnode:10.10 peripheral blood:- spleen:- thymus:- bone marrow:- adipose:- bone:- skin:-
GeneChip cerebrum:4.59 cerebellum:4.86 brain stem:4.61 corpus callosum/glia:4.82 pineal gland:- peripheral nerve:4.60 spine:4.67 retina:- eye:- artery/aorta:4.48 vein:4.72 lymphnode:5.44 peripheral blood:- spleen:5.13 thymus:5.22 bone marrow:4.82 adipose:4.57 bone:- skin:4.52
CAGE cerebrum:1.71 cerebellum:- brain stem:1.92 corpus callosum/glia:2.14 pineal gland:1.59 peripheral nerve:- spine:2.32 retina:- eye:- artery/aorta:1.85 vein:3.12 lymphnode:3.86 peripheral blood:- spleen:4.53 thymus:3.37 bone marrow:- adipose:2.12 bone:- skin:-
RNA-seq cerebrum:0.58 cerebellum:- brain stem:- corpus callosum/glia:- pineal gland:- peripheral nerve:- spine:- retina:- eye:- artery/aorta:- vein:- lymphnode:1.66 peripheral blood:- spleen:- thymus:- bone marrow:- adipose:1.04 bone:- skin:-
reproductive muscular alimentary liver lung urinary endo/exo-crine
EST uterus:82 placenta:535.50 prostate:- ovary:- testis:- heart:- muscle:- esophagus:- stomach:- intestine:- colon:-     liver/hepato:-        lung:-    bladder:- kidney:- pituitary:- thyroid/parathyroid:- adrenal gland:- pancreas:- breast:- salivary:-
GeneChip uterus:4.34 placenta:12.09 prostate:4 ovary:4.60 testis:4.09 heart:4.59 muscle:4.51 esophagus:4.60 stomach:4.64 intestine:4.59 colon:4.78 liver/hepato:4.65 lung:4.69 bladder:- kidney:4.45 pituitary:4.36 thyroid/parathyroid:4.34 adrenal gland:4.86 pancreas:4.85 breast:4.52 salivary:4.55
CAGE uterus:1.13 placenta:7.92 prostate:1.53 ovary:1.27 testis:1.64 heart:1.52 muscle:0.87 esophagus:1.08 stomach:- intestine:2.17 colon:1.73     liver/hepato:2.48    lung:2.06 bladder:1.32 kidney:2.20 pituitary:1.77 thyroid/parathyroid:1.09 adrenal gland:- pancreas:1.87 breast:2.34 salivary:0.83
RNA-seq uterus:- placenta:- prostate:0.70 ovary:0.40 testis:0.55 heart:0.64 muscle:0 esophagus:- stomach:- intestine:- colon:0.14     liver/hepato:1.06        lung:0.79    bladder:- kidney:0.90 pituitary:- thyroid/parathyroid:0.45 adrenal gland:2.77 pancreas:- breast:0.66 salivary:-

Gene Information

IDs

Refseq ID NM_005755
Gene ID 10148
Unigene ID Hs.501452
Probe set ID 219424_at  [HG-U133_Plus_2]
Ensembl ID ENSG00000105246
GTEx ID ENSG00000105246

Orthologous Gene

Mouse[1]  NM_015766
Rat[1]  NM_015766

Chromosomal Region

19p13.3  [4,229,540  -  4,237,515]

Gene Family (Interpro ID)

IPR003961  Fibronectin, type III
IPR008957  Fibronectin, type III-like fold

Link to Pubmed  (Pubmed ID)

934235
8551575
9342359
12121660
12477932
14743498
15057824
15170639
15231748
15489334
16189514
18167155
18336908
18784808
19556516
21285006
21931777
22343630
22438968
22836044
23154182
23562195
23619469
23845089
23898208
23904441
24376289

Gene Ontology  (GO ID)

Biological Process

GO:0019221  cytokine-mediated signaling pathway
GO:0006959  humoral immune response
GO:0046641  positive regulation of alpha-beta T cell proliferation
GO:0045078  positive regulation of interferon-gamma biosynthetic process
GO:0042088  T-helper 1 type immune response

Cellular Component

GO:0005615  extracellular space
GO:0005886  plasma membrane

Molecular Function

GO:0005125  cytokine activity
GO:0004896  cytokine receptor activity
GO:0045523  interleukin-27 receptor binding