potassium large conductance calcium-activated channel, subfamily M, beta member 2

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Synonym

Maxi K channel subunit beta 2, KCNMB2, Slo-beta 2, Hbeta2, Hbeta3, Charybdotoxin receptor subunit beta 2, BK channel subunit beta 2, BKbeta2, Calcium-activated potassium channel subunit beta 2, K(VCA)beta 2, MGC22431

Expression Pattern

Choropleth map on BodyParts3D

Choropleth maps on 3D human body images were generated by the relative gene expression values measured by GeneChip.

Classification in 40 Organs

brain blood connective
EST cerebrum:33.20 cerebellum:- brain stem:- corpus callosum/glia:- pineal gland:- peripheral nerve:30.70 spine:- retina:237.30 eye:- artery/aorta:- vein:- lymphnode:- peripheral blood:- spleen:56.70 thymus:- bone marrow:19.70 adipose:- bone:- skin:38.40
GeneChip cerebrum:4.83 cerebellum:4.84 brain stem:4.79 corpus callosum/glia:4.63 pineal gland:- peripheral nerve:4.70 spine:4.81 retina:- eye:- artery/aorta:4.60 vein:4.93 lymphnode:4.55 peripheral blood:- spleen:4.58 thymus:4.10 bone marrow:4.83 adipose:4.54 bone:- skin:4.34
CAGE cerebrum:2.10 cerebellum:- brain stem:1.96 corpus callosum/glia:1.58 pineal gland:0.92 peripheral nerve:- spine:1.78 retina:- eye:- artery/aorta:0.79 vein:0 lymphnode:0 peripheral blood:- spleen:0.25 thymus:0 bone marrow:- adipose:0 bone:- skin:-
RNA-seq cerebrum:0.00 cerebellum:- brain stem:- corpus callosum/glia:- pineal gland:- peripheral nerve:- spine:- retina:- eye:- artery/aorta:- vein:- lymphnode:0 peripheral blood:- spleen:- thymus:- bone marrow:- adipose:0 bone:- skin:-
reproductive muscular alimentary liver lung urinary endo/exo-crine
EST uterus:27.30 placenta:7.30 prostate:11.30 ovary:74.50 testis:4.30 heart:12.80 muscle:- esophagus:- stomach:21.20 intestine:- colon:8.50     liver/hepato:10.60        lung:9.80    bladder:- kidney:83.20 pituitary:- thyroid/parathyroid:- adrenal gland:- pancreas:240.10 breast:18.60 salivary:-
GeneChip uterus:4.52 placenta:4.81 prostate:4.22 ovary:5.07 testis:4.27 heart:5.21 muscle:4.73 esophagus:4.41 stomach:4.74 intestine:4.58 colon:4.85 liver/hepato:4.87 lung:4.60 bladder:- kidney:5.15 pituitary:5.09 thyroid/parathyroid:4.61 adrenal gland:4.80 pancreas:5.17 breast:4.34 salivary:4.90
CAGE uterus:2.07 placenta:0 prostate:0.70 ovary:2.45 testis:0.98 heart:1.56 muscle:0.05 esophagus:0.33 stomach:- intestine:0.66 colon:0.38     liver/hepato:0.14    lung:1.14 bladder:0.58 kidney:1.63 pituitary:2.93 thyroid/parathyroid:1.13 adrenal gland:- pancreas:1.59 breast:0 salivary:0.36
RNA-seq uterus:- placenta:- prostate:0.22 ovary:1.33 testis:0.94 heart:0.00 muscle:0 esophagus:- stomach:- intestine:- colon:0.00     liver/hepato:0.00        lung:1.07    bladder:- kidney:1.04 pituitary:- thyroid/parathyroid:0.36 adrenal gland:0.00 pancreas:- breast:0.11 salivary:-

Gene Information

IDs

Refseq ID NM_005832
Gene ID 10242
Unigene ID Hs.478368
Probe set ID 221097_s_at  [HG-U133_Plus_2]
Ensembl ID ENSG00000197584
GTEx ID ENSG00000197584

Orthologous Gene

Mouse[2]  NM_028231
Rat[2]  NM_176861

Chromosomal Region

3q26.32  [177,990,720  -  178,562,217]

Gene Family (Interpro ID)

-

Link to Pubmed  (Pubmed ID)

8889548
10097176
10377337
10692449
10758170
10766764
10792058
11181995
11517232
12136044
12477932
12566540
14522958
15489334
16344560
16446507
17460083
17521822
19204046
19684603
20859064
21832049
22688191
23291589
23825428
24414257

Gene Ontology  (GO ID)

Biological Process

GO:0007596  blood coagulation
GO:0005513  detection of calcium ion
GO:0006813  potassium ion transport
GO:0001508  regulation of action potential
GO:0019228  regulation of action potential in neuron
GO:0019229  regulation of vasoconstriction
GO:0007268  synaptic transmission

Cellular Component

GO:0005887  integral to plasma membrane
GO:0005886  plasma membrane
GO:0008076  voltage-gated potassium channel complex

Molecular Function

GO:0015269  calcium-activated potassium channel activity
GO:0008200  ion channel inhibitor activity
GO:0015459  potassium channel regulator activity