receptor (G protein-coupled) activity modifying protein 2

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Synonym

CRLR activity-modifying protein 2, receptor (calcitonin) activity modifying protein 2, Receptor activity-modifying protein 2 precursor, RAMP2, receptor activity modifying protein 2

Expression Pattern

Choropleth map on BodyParts3D

Choropleth maps on 3D human body images were generated by the relative gene expression values measured by GeneChip.

Classification in 40 Organs

brain blood connective
EST cerebrum:13 cerebellum:- brain stem:- corpus callosum/glia:- pineal gland:- peripheral nerve:- spine:- retina:237.30 eye:17.60 artery/aorta:- vein:- lymphnode:- peripheral blood:- spleen:75.60 thymus:- bone marrow:- adipose:- bone:12.80 skin:9.60
GeneChip cerebrum:6.01 cerebellum:5.77 brain stem:6.17 corpus callosum/glia:5.85 pineal gland:- peripheral nerve:6.48 spine:6.06 retina:- eye:- artery/aorta:6.80 vein:6.86 lymphnode:6.54 peripheral blood:- spleen:6.38 thymus:5.25 bone marrow:5.82 adipose:7.50 bone:- skin:6.82
CAGE cerebrum:2.64 cerebellum:- brain stem:2.87 corpus callosum/glia:3.42 pineal gland:2.07 peripheral nerve:- spine:2.74 retina:- eye:- artery/aorta:3.70 vein:4.64 lymphnode:3.62 peripheral blood:- spleen:3.74 thymus:2.29 bone marrow:- adipose:4.78 bone:- skin:-
RNA-seq cerebrum:2.81 cerebellum:- brain stem:- corpus callosum/glia:- pineal gland:- peripheral nerve:- spine:- retina:- eye:- artery/aorta:- vein:- lymphnode:4.99 peripheral blood:- spleen:- thymus:- bone marrow:- adipose:6.47 bone:- skin:-
reproductive muscular alimentary liver lung urinary endo/exo-crine
EST uterus:- placenta:25.50 prostate:11.30 ovary:- testis:- heart:25.50 muscle:- esophagus:- stomach:- intestine:- colon:-     liver/hepato:-        lung:44    bladder:- kidney:- pituitary:- thyroid/parathyroid:- adrenal gland:- pancreas:26.70 breast:- salivary:-
GeneChip uterus:6.76 placenta:6.94 prostate:6.07 ovary:6.04 testis:5.73 heart:7.22 muscle:6.43 esophagus:6.48 stomach:6.50 intestine:6.69 colon:6.74 liver/hepato:6.49 lung:7.93 bladder:- kidney:6.78 pituitary:6.07 thyroid/parathyroid:6.60 adrenal gland:6.94 pancreas:6.80 breast:6.85 salivary:6.17
CAGE uterus:4.71 placenta:4.91 prostate:4.25 ovary:3.84 testis:3.14 heart:4.32 muscle:3.25 esophagus:3.96 stomach:- intestine:3.20 colon:3.05     liver/hepato:3.50    lung:5.04 bladder:3.60 kidney:3.88 pituitary:1.75 thyroid/parathyroid:3.06 adrenal gland:- pancreas:3.13 breast:4.43 salivary:3.30
RNA-seq uterus:- placenta:- prostate:4.94 ovary:4.79 testis:4.31 heart:3.84 muscle:3.32 esophagus:- stomach:- intestine:- colon:4.23     liver/hepato:2.38        lung:6.23    bladder:- kidney:4.00 pituitary:- thyroid/parathyroid:4.54 adrenal gland:6.36 pancreas:- breast:5.79 salivary:-

Gene Information

IDs

Refseq ID NM_005854
Gene ID 10266
Unigene ID Hs.514193
Probe set ID 205779_at  [HG-U133_Plus_2]
Ensembl ID ENSG00000131477
GTEx ID ENSG00000131477

Orthologous Gene

Mouse[4]  NM_019444, NM_026776
Rat[1]  NM_031646, NM_026776

Chromosomal Region

17q21.31  [40,913,212  -  40,915,055]

Gene Family (Interpro ID)

-

Link to Pubmed  (Pubmed ID)

9620797
10217420
10354609
10767413
10882736
11060459
11387328
11591721
11754963
11973435
12036966
12093471
12419522
12446722
12477932
12565884
14722252
15245870
15300632
15489334
15613468
16410241
16531504
16912219
16964401
17671114
18097473
18240029
18577758
18593822
18835256
19210874
19913121
20074556
20628086
22102369
24169318

Gene Ontology  (GO ID)

Biological Process

GO:0034333  adherens junction assembly
GO:0001525  angiogenesis
GO:0070831  basement membrane assembly
GO:0006816  calcium ion transport
GO:0006171  cAMP biosynthetic process
GO:0032870  cellular response to hormone stimulus
GO:0007565  female pregnancy
GO:0007186  G-protein coupled receptor protein signaling pathway
GO:0007507  heart development
GO:0006886  intracellular protein transport
GO:0043116  negative regulation of vascular permeability
GO:0045766  positive regulation of angiogenesis
GO:0030819  positive regulation of cAMP biosynthetic process
GO:0010628  positive regulation of gene expression
GO:0015031  protein transport
GO:0031623  receptor internalization
GO:0008217  regulation of blood pressure
GO:0008277  regulation of G-protein coupled receptor protein signaling pathway
GO:0032355  response to estradiol stimulus
GO:0001666  response to hypoxia
GO:0032570  response to progesterone stimulus
GO:0002040  sprouting angiogenesis
GO:0070830  tight junction assembly
GO:0001570  vasculogenesis

Cellular Component

GO:0009986  cell surface
GO:0005905  coated pit
GO:0005737  cytoplasm
GO:0005887  integral to plasma membrane
GO:0005764  lysosome
GO:0005886  plasma membrane
GO:0043235  receptor complex

Molecular Function

GO:0015026  coreceptor activity
GO:0005515  protein binding
GO:0008565  protein transporter activity