ubiquitination factor E4B (UFD2 homolog, yeast)

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Synonym

KIAA0684, Homozygously deleted in neuroblastoma 1, ubiquitination factor E4B (UFD2 homolog, yeast), HDNB1, Ubiquitin conjugation factor E4 B, UFD2, Ubiquitin fusion degradation protein 2, UBOX3, E4, UBE4B

Expression Pattern

Choropleth map on BodyParts3D

Choropleth maps on 3D human body images were generated by the relative gene expression values measured by GeneChip.

Classification in 40 Organs

brain blood connective
EST nodata
GeneChip cerebrum:7.35 cerebellum:7.52 brain stem:7.37 corpus callosum/glia:7.39 pineal gland:- peripheral nerve:7.42 spine:7.02 retina:- eye:- artery/aorta:7.28 vein:7.13 lymphnode:7.07 peripheral blood:- spleen:6.91 thymus:7.19 bone marrow:6.90 adipose:7.12 bone:- skin:7.34
CAGE cerebrum:3.75 cerebellum:- brain stem:3.93 corpus callosum/glia:4.22 pineal gland:3.59 peripheral nerve:- spine:3.48 retina:- eye:- artery/aorta:3.61 vein:3.22 lymphnode:3.48 peripheral blood:- spleen:3.41 thymus:3.53 bone marrow:- adipose:3.48 bone:- skin:-
RNA-seq cerebrum:3.40 cerebellum:- brain stem:- corpus callosum/glia:- pineal gland:- peripheral nerve:- spine:- retina:- eye:- artery/aorta:- vein:- lymphnode:3.24 peripheral blood:- spleen:- thymus:- bone marrow:- adipose:3.46 bone:- skin:-
reproductive muscular alimentary liver lung urinary endo/exo-crine
EST nodata
GeneChip uterus:7.30 placenta:7.29 prostate:7.32 ovary:7.36 testis:6.78 heart:7.34 muscle:7.77 esophagus:7.41 stomach:7.17 intestine:7.20 colon:6.98 liver/hepato:7.26 lung:6.96 bladder:- kidney:7.20 pituitary:7.43 thyroid/parathyroid:7.42 adrenal gland:7.54 pancreas:7.43 breast:7.20 salivary:7.19
CAGE uterus:3.84 placenta:3.78 prostate:3.65 ovary:3.47 testis:3.36 heart:3.45 muscle:3.19 esophagus:3.88 stomach:- intestine:3.45 colon:3.39     liver/hepato:3.37    lung:3.28 bladder:3.75 kidney:3.35 pituitary:3.67 thyroid/parathyroid:3.52 adrenal gland:- pancreas:3.90 breast:2.69 salivary:3.34
RNA-seq uterus:- placenta:- prostate:3.96 ovary:3.40 testis:3.33 heart:2.79 muscle:3.59 esophagus:- stomach:- intestine:- colon:4.08     liver/hepato:2.46        lung:2.10    bladder:- kidney:3.12 pituitary:- thyroid/parathyroid:3.77 adrenal gland:2.64 pancreas:- breast:3.57 salivary:-

Gene Information

IDs

Refseq ID NM_006048
Gene ID 10277
Unigene ID -
Probe set ID 202317_s_at  [HG-U133_Plus_2]
Ensembl ID ENSG00000130939
GTEx ID ENSG00000130939

Orthologous Gene

Mouse[4]  NM_022022
Rat[4]  NM_022022

Chromosomal Region

1p36.22  [10,092,890  -  10,241,297]

Gene Family (Interpro ID)

IPR003613  U box domain
IPR013083  Zinc finger, RING/FYVE/PHD-type

Link to Pubmed  (Pubmed ID)

9653645
9734811
10089879
10980605
11802788
12477932
12504083
12700669
14702039
14749733
15189447
15302935
15466860
15489334
16170377
16344560
16710414
16870146
17081983
17955473
18022694
18234089
18418053
18654987
18775313
19175675
19322201
19805293
19889839
20017557
20414249
20676096
20696396
21139048
21282470
21317885
21890473
21906983
21963094
21987572
22045814
22124266
22174917
22505724
22863883
22939629
22990745
23000965
23550736
24250222
24344129
24587254

Gene Ontology  (GO ID)

Biological Process

GO:0008626  induction of apoptosis by granzyme
GO:0042787  protein ubiquitination during ubiquitin-dependent protein catabolic process
GO:0009411  response to UV

Cellular Component

GO:0005737  cytoplasm
GO:0000151  ubiquitin ligase complex

Molecular Function

GO:0019899  enzyme binding
GO:0034450  ubiquitin-ubiquitin ligase activity