splicing factor 3a, subunit 1, 120kDa

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Synonym

PRPF21, PRP21, Spliceosome-associated protein 114, SF3A1, Prp21, SF3a120, splicing factor 3a, subunit 1, 120kDa, Splicing factor 3 subunit 1, SAP 114, SF3A120, SAP114

Expression Pattern

Choropleth map on BodyParts3D

Choropleth maps on 3D human body images were generated by the relative gene expression values measured by GeneChip.

Classification in 40 Organs

brain blood connective
EST cerebrum:220.40 cerebellum:289.70 brain stem:- corpus callosum/glia:145.80 pineal gland:148.30 peripheral nerve:30.70 spine:112.30 retina:- eye:129.30 artery/aorta:119.90 vein:- lymphnode:161.80 peripheral blood:145.70 spleen:208 thymus:889 bone marrow:118.10 adipose:40.30 bone:243.10 skin:105.60
GeneChip cerebrum:7.37 cerebellum:7.88 brain stem:7.19 corpus callosum/glia:7.53 pineal gland:- peripheral nerve:7.72 spine:7.39 retina:- eye:- artery/aorta:7.67 vein:7.85 lymphnode:7.98 peripheral blood:- spleen:7.92 thymus:7.99 bone marrow:8.10 adipose:7.86 bone:- skin:8.09
CAGE cerebrum:4.99 cerebellum:- brain stem:4.67 corpus callosum/glia:4.82 pineal gland:5.33 peripheral nerve:- spine:4.79 retina:- eye:- artery/aorta:4.91 vein:5.32 lymphnode:5.25 peripheral blood:- spleen:5.04 thymus:5.32 bone marrow:- adipose:4.98 bone:- skin:-
RNA-seq cerebrum:3.73 cerebellum:- brain stem:- corpus callosum/glia:- pineal gland:- peripheral nerve:- spine:- retina:- eye:- artery/aorta:- vein:- lymphnode:4.43 peripheral blood:- spleen:- thymus:- bone marrow:- adipose:4.62 bone:- skin:-
reproductive muscular alimentary liver lung urinary endo/exo-crine
EST uterus:200.50 placenta:80.10 prostate:101.40 ovary:- testis:250.90 heart:51.10 muscle:80.40 esophagus:- stomach:21.20 intestine:194.40 colon:33.90     liver/hepato:168.90        lung:78.20    bladder:628.10 kidney:104 pituitary:232 thyroid/parathyroid:- adrenal gland:101.60 pancreas:17.80 breast:92.90 salivary:-
GeneChip uterus:7.79 placenta:7.44 prostate:7.86 ovary:8.08 testis:7.94 heart:7.37 muscle:7.80 esophagus:7.79 stomach:7.62 intestine:7.79 colon:7.84 liver/hepato:7.28 lung:7.83 bladder:- kidney:7.61 pituitary:7.64 thyroid/parathyroid:8.05 adrenal gland:7.43 pancreas:7.71 breast:8.21 salivary:7.70
CAGE uterus:5.03 placenta:4.76 prostate:4.94 ovary:5.17 testis:5.82 heart:4.92 muscle:4.97 esophagus:4.79 stomach:- intestine:4.70 colon:4.94     liver/hepato:4.79    lung:4.96 bladder:4.92 kidney:4.66 pituitary:4.95 thyroid/parathyroid:5.01 adrenal gland:- pancreas:4.77 breast:5.14 salivary:5.03
RNA-seq uterus:- placenta:- prostate:4.95 ovary:4.95 testis:5.40 heart:3.66 muscle:5.44 esophagus:- stomach:- intestine:- colon:4.35     liver/hepato:3.03        lung:4.19    bladder:- kidney:4.07 pituitary:- thyroid/parathyroid:4.73 adrenal gland:4.28 pancreas:- breast:4.16 salivary:-

Gene Information

IDs

Refseq ID NM_005877
Gene ID 10291
Unigene ID Hs.406277
Probe set ID 201356_at  [HG-U133_Plus_2]
Ensembl ID ENSG00000099995
GTEx ID ENSG00000099995

Orthologous Gene

Mouse[2]  NM_026175
Rat[1]  NM_001107235

Chromosomal Region

22q12.2  [30,727,979  -  30,752,936]

Gene Family (Interpro ID)

IPR000626  Ubiquitin
IPR019955  Ubiquitin supergroup

Link to Pubmed  (Pubmed ID)

7489498
8022796
8718683
9731529
9847074
10385517
10591208
10882114
10976766
11013263
11101529
11337467
11500380
11533230
11991638
12226669
12234937
12477932
15302935
15316075
15456888
15461802
15489334
15527767
15592455
15647371
15761153
16055720
16751776
17081983
17098193
17332742
17353931
17643375
18029348
18854154
19471022
19615732
19850743
20360068
20379614
20562859
20639865
21081666
21139048
21145461
21693764
21890473
21906983
22113938
22174317
22178446
22365833
22586326
22751105
22797925
22863883
22939629
22990118
23000965
23084401
23151878
23184937
23752268
23870195
24332808
24457600
24550385
24657165
24816145

Gene Ontology  (GO ID)

Biological Process

GO:0010467  gene expression
GO:0006397  mRNA processing
GO:0000389  nuclear mRNA 3'-splice site recognition
GO:0000398  nuclear mRNA splicing, via spliceosome
GO:0008380  RNA splicing

Cellular Component

GO:0071013  catalytic step 2 spliceosome
GO:0005730  nucleolus
GO:0005654  nucleoplasm
GO:0005634  nucleus
GO:0005681  spliceosomal complex
GO:0005684  U2-type spliceosomal complex

Molecular Function

GO:0005515  protein binding
GO:0003723  RNA binding