tryptophanyl tRNA synthetase 2, mitochondrial

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Synonym

(Mt)TrpRS, TrpRS, Tryptophan--tRNA ligase, tryptophanyl tRNA synthetase 2 (mitochondrial), WARS2

Expression Pattern

Choropleth map on BodyParts3D

Choropleth maps on 3D human body images were generated by the relative gene expression values measured by GeneChip.

Classification in 40 Organs

brain blood connective
EST cerebrum:35.60 cerebellum:25.20 brain stem:- corpus callosum/glia:- pineal gland:- peripheral nerve:- spine:112.30 retina:- eye:17.60 artery/aorta:60 vein:- lymphnode:50.60 peripheral blood:18.20 spleen:- thymus:51.50 bone marrow:19.70 adipose:40.30 bone:12.80 skin:33.60
GeneChip cerebrum:3.77 cerebellum:3.55 brain stem:3.77 corpus callosum/glia:3.63 pineal gland:- peripheral nerve:4.11 spine:3.58 retina:- eye:- artery/aorta:4.27 vein:4.13 lymphnode:4.23 peripheral blood:- spleen:3.99 thymus:4.27 bone marrow:3.84 adipose:4.13 bone:- skin:4.44
CAGE cerebrum:2.25 cerebellum:- brain stem:2.41 corpus callosum/glia:2.57 pineal gland:2.47 peripheral nerve:- spine:2.36 retina:- eye:- artery/aorta:2.70 vein:2.89 lymphnode:2.99 peripheral blood:- spleen:2.70 thymus:2.70 bone marrow:- adipose:3.25 bone:- skin:-
RNA-seq cerebrum:0.12 cerebellum:- brain stem:- corpus callosum/glia:- pineal gland:- peripheral nerve:- spine:- retina:- eye:- artery/aorta:- vein:- lymphnode:0.24 peripheral blood:- spleen:- thymus:- bone marrow:- adipose:0.89 bone:- skin:-
reproductive muscular alimentary liver lung urinary endo/exo-crine
EST uterus:36.50 placenta:25.50 prostate:56.30 ovary:37.30 testis:30.30 heart:- muscle:- esophagus:- stomach:63.70 intestine:64.80 colon:25.40     liver/hepato:-        lung:9.80    bladder:125.60 kidney:104 pituitary:- thyroid/parathyroid:- adrenal gland:- pancreas:8.90 breast:9.30 salivary:-
GeneChip uterus:4.46 placenta:4 prostate:4.58 ovary:4.57 testis:4.84 heart:4.19 muscle:4.35 esophagus:4.37 stomach:4.08 intestine:4.09 colon:4.36 liver/hepato:3.85 lung:4.04 bladder:- kidney:4.32 pituitary:4.05 thyroid/parathyroid:4.34 adrenal gland:4.37 pancreas:4.39 breast:4.31 salivary:4.05
CAGE uterus:3.16 placenta:3.04 prostate:3.10 ovary:3.07 testis:2.70 heart:2.68 muscle:2.82 esophagus:3.02 stomach:- intestine:2.95 colon:2.68     liver/hepato:2.93    lung:2.84 bladder:3.05 kidney:2.97 pituitary:2.85 thyroid/parathyroid:2.91 adrenal gland:- pancreas:3.16 breast:2.59 salivary:2.75
RNA-seq uterus:- placenta:- prostate:0.00 ovary:0.17 testis:0.53 heart:0.00 muscle:0.96 esophagus:- stomach:- intestine:- colon:1.23     liver/hepato:0.12        lung:0.25    bladder:- kidney:0.00 pituitary:- thyroid/parathyroid:0.57 adrenal gland:0.68 pancreas:- breast:0.30 salivary:-

Gene Information

IDs

Refseq ID NM_201263
Gene ID 10352
Unigene ID Hs.523506
Probe set ID 218766_s_at  [HG-U133_Plus_2]
Ensembl ID ENSG00000116874
GTEx ID ENSG00000116874

Orthologous Gene

Mouse[1]  NM_027462
Rat[1]  NM_001168641

Chromosomal Region

1p12  [119,573,839  -  119,683,294]

Gene Family (Interpro ID)

-

Link to Pubmed  (Pubmed ID)

8125298
10072595
10828066
12477932
14757836
15489334
16341674
16710414
17207965
17726052
20877624
20935629
21832049
24250222
24816145

Gene Ontology  (GO ID)

Biological Process

GO:0010467  gene expression
GO:0006418  tRNA aminoacylation for protein translation
GO:0006436  tryptophanyl-tRNA aminoacylation
GO:0001570  vasculogenesis

Cellular Component

GO:0005759  mitochondrial matrix

Molecular Function

GO:0005524  ATP binding
GO:0004830  tryptophan-tRNA ligase activity