myosin, light chain 12B, regulatory

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Synonym

MLC-B, myosin regulatory light chain MRLC2

Expression Pattern

Choropleth map on BodyParts3D

Choropleth maps on 3D human body images were generated by the relative gene expression values measured by GeneChip.

Classification in 40 Organs

brain blood connective
EST cerebrum:78.20 cerebellum:- brain stem:- corpus callosum/glia:- pineal gland:148.30 peripheral nerve:276 spine:- retina:237.30 eye:235.10 artery/aorta:89.90 vein:533.20 lymphnode:101.10 peripheral blood:127.50 spleen:37.80 thymus:12.90 bone marrow:216.50 adipose:121 bone:51.20 skin:499.20
GeneChip cerebrum:9.25 cerebellum:9.14 brain stem:9.62 corpus callosum/glia:8.78 pineal gland:- peripheral nerve:10.17 spine:9.23 retina:- eye:- artery/aorta:10.18 vein:10.26 lymphnode:10.23 peripheral blood:- spleen:10.22 thymus:10.25 bone marrow:9.96 adipose:10.35 bone:- skin:10.39
CAGE cerebrum:4.71 cerebellum:- brain stem:4.82 corpus callosum/glia:4.21 pineal gland:4.66 peripheral nerve:- spine:4.69 retina:- eye:- artery/aorta:5.62 vein:5.23 lymphnode:5.30 peripheral blood:- spleen:5.24 thymus:5.13 bone marrow:- adipose:5.33 bone:- skin:-
RNA-seq cerebrum:5.74 cerebellum:- brain stem:- corpus callosum/glia:- pineal gland:- peripheral nerve:- spine:- retina:- eye:- artery/aorta:- vein:- lymphnode:3.58 peripheral blood:- spleen:- thymus:- bone marrow:- adipose:2.57 bone:- skin:-
reproductive muscular alimentary liver lung urinary endo/exo-crine
EST uterus:191.40 placenta:178.50 prostate:112.60 ovary:111.80 testis:60.60 heart:306.50 muscle:20.10 esophagus:- stomach:361.10 intestine:129.60 colon:169.60     liver/hepato:105.60        lung:219.90    bladder:- kidney:20.80 pituitary:- thyroid/parathyroid:163.70 adrenal gland:101.60 pancreas:293.40 breast:585.50 salivary:-
GeneChip uterus:10.28 placenta:10.72 prostate:10.48 ovary:10.49 testis:10.03 heart:9.89 muscle:9.21 esophagus:10.72 stomach:10.06 intestine:10.20 colon:10.12 liver/hepato:9.83 lung:10.64 bladder:- kidney:10.67 pituitary:9.77 thyroid/parathyroid:10.65 adrenal gland:10.84 pancreas:9.70 breast:10.34 salivary:10.16
CAGE uterus:5.03 placenta:5.99 prostate:5.22 ovary:5.10 testis:5.03 heart:5.16 muscle:5.15 esophagus:5.80 stomach:- intestine:5.97 colon:5.37     liver/hepato:5.62    lung:5.84 bladder:5.21 kidney:6.10 pituitary:4.86 thyroid/parathyroid:5.73 adrenal gland:- pancreas:4.92 breast:5.37 salivary:4.92
RNA-seq uterus:- placenta:- prostate:3.16 ovary:3.62 testis:6.48 heart:2.86 muscle:0.00 esophagus:- stomach:- intestine:- colon:5.87     liver/hepato:3.38        lung:3.30    bladder:- kidney:7.63 pituitary:- thyroid/parathyroid:3.79 adrenal gland:3.51 pancreas:- breast:5.51 salivary:-

Gene Information

IDs

Refseq ID NM_001144945
Gene ID 103910
Unigene ID Hs.464472
Probe set ID 221474_at  [HG-U133_Plus_2]
Ensembl ID ENSG00000118680
GTEx ID ENSG00000118680

Orthologous Gene

Mouse[1]  NM_023402
Rat [0]  

Chromosomal Region

18p11.31  [3,261,907  -  3,278,282]

Gene Family (Interpro ID)

IPR002048  Calcium-binding EF-hand
IPR018249  EF-HAND 2

Link to Pubmed  (Pubmed ID)

10593918
11942626
12477932
14627618
15146197
15188056
15616583
15946647
17620599
19165527
19328794
19471022
19615732
19794400
20473970
20618440
20876399
21139048
21145461
21319273
21853274
21890473
21906983
21963094
21987572
22136066
22166199
22374324
22505724
22623428
22808956
23000965
23398456
23862649
24816145

Gene Ontology  (GO ID)

Biological Process

GO:0007411  axon guidance
GO:0006936  muscle contraction
GO:0008360  regulation of cell shape

Cellular Component

GO:0045177  apical part of cell
GO:0005829  cytosol
GO:0016460  myosin II complex
GO:0001725  stress fiber
GO:0030018  Z disc

Molecular Function

GO:0005509  calcium ion binding
GO:0005515  protein binding