deleted in liver cancer 1

Synonym

FLJ21120, Dlc-1, HP protein, Rho-GTPase-activating protein 7, Rho-type GTPase-activating protein 7, StARD12, START domain-containing protein 12, STARD12, p122-RhoGAP, Deleted in liver cancer 1 protein, KIAA1723, StAR-related lipid transfer protein 12, deleted in liver cancer 1, ARHGAP7, DLC-1

normal 40 tissues
cell lines, primary cells, adult tissues and fetal tissues (FANTOM5 CAGE)

Choropleth map on BodyParts3D

Choropleth maps on 3D human body images were generated by the relative gene expression values measured by GeneChip.

Classification in 40 Organs

brain

blood

connective

EST

cerebrum:79.40

cerebellum:37.80

brain stem:-

corpus callosum/glia:87.50

pineal gland:-

peripheral nerve:184

spine:336.90

retina:118.60

eye:135.20

artery/aorta:329.70

vein:66.60

lymphnode:10.10

peripheral blood:-

spleen:151.30

thymus:51.50

bone marrow:78.70

adipose:524.30

bone:115.20

skin:153.60

GeneChip

cerebrum:7.70

cerebellum:5.89

brain stem:7.79

corpus callosum/glia:7.67

pineal gland:-

peripheral nerve:7.84

spine:7.62

retina:-

eye:-

artery/aorta:8.22

vein:8.34

lymphnode:6.20

peripheral blood:-

spleen:7.97

thymus:5.35

bone marrow:5.95

adipose:8.54

bone:-

skin:7.05

CAGE

cerebrum:3.97

cerebellum:-

brain stem:4.33

corpus callosum/glia:4.31

pineal gland:3.52

peripheral nerve:-

spine:4.02

retina:-

eye:-

artery/aorta:4.57

vein:4.21

lymphnode:3.21

peripheral blood:-

spleen:4.65

thymus:1.54

bone marrow:-

adipose:5.28

bone:-

skin:-

RNA-seq

cerebrum:1.30

cerebellum:-

brain stem:-

corpus callosum/glia:-

pineal gland:-

peripheral nerve:-

spine:-

retina:-

eye:-

artery/aorta:-

vein:-

lymphnode:1.14

peripheral blood:-

spleen:-

thymus:-

bone marrow:-

adipose:2.90

bone:-

skin:-

reproductive

muscular

alimentary

liver

lung

urinary

endo/exo-crine

EST

uterus:136.70

placenta:102

prostate:78.90

ovary:149.10

testis:51.90

heart:319.30

muscle:60.30

esophagus:-

stomach:-

intestine:-

colon:25.40

liver/hepato:21.10

lung:317.70

bladder:-

kidney:62.40

pituitary:-

thyroid/parathyroid:163.70

adrenal gland:253.90

pancreas:80

breast:195.20

salivary:-

GeneChip

uterus:7.78

placenta:7.21

prostate:6.87

ovary:7.23

testis:6.59

heart:8.20

muscle:6.69

esophagus:6.54

stomach:7.75

intestine:7.13

colon:7.14

liver/hepato:7.78

lung:9.81

bladder:-

kidney:7.35

pituitary:6.13

thyroid/parathyroid:7.58

adrenal gland:7.82

pancreas:5.53

breast:8.17

salivary:5.37

CAGE

uterus:4.38

placenta:4.15

prostate:3.86

ovary:4.06

testis:3.59

heart:4.72

muscle:3.58

esophagus:4.03

stomach:-

intestine:3.92

colon:4.07

liver/hepato:4.91

lung:5.59

bladder:4.19

kidney:3.84

pituitary:3.30

thyroid/parathyroid:3.24

adrenal gland:-

pancreas:3.20

breast:5.40

salivary:2.66

RNA-seq

uterus:-

placenta:-

prostate:1.33

ovary:1.86

testis:2.01

heart:1.63

muscle:0.98

esophagus:-

stomach:-

intestine:-

colon:1.74

liver/hepato:0.02

lung:1.16

bladder:-

kidney:0.15

pituitary:-

thyroid/parathyroid:1.33

adrenal gland:1.45

pancreas:-

breast:1.72

salivary:-

IDs

Refseq ID	NM_182643
Gene ID	10395
Unigene ID	Hs.134296
Probe set ID	210762_s_at [HG-U133_Plus_2]
Ensembl ID	ENSG00000164741
GTEx ID	ENSG00000164741

Orthologous Gene

Mouse[2]	NM_001194940, NM_001194941, NM_015802, NM_178735
Rat[2]	NM_001127446, NM_001194941, NM_015802, NM_178735

Chromosomal Region

8p22 [12,940,870 - 13,373,167]

Search genes near this gene
- Between -5kb and +5kb
- Between -10kb and +10kb

Gene Family (Interpro ID)

IPR008936	Rho GTPase activation protein
IPR000198	RhoGAP

Link to Pubmed (Pubmed ID)

Gene Ontology (GO ID)

Biological Process

GO:0030036	actin cytoskeleton organization
GO:0006919	activation of caspase activity
GO:0048041	focal adhesion formation
GO:0030900	forebrain development
GO:0003007	heart morphogenesis
GO:0021575	hindbrain morphogenesis
GO:0006917	induction of apoptosis
GO:0030336	negative regulation of cell migration
GO:0008285	negative regulation of cell proliferation
GO:0035024	negative regulation of Rho protein signal transduction
GO:0051497	negative regulation of stress fiber formation
GO:0001843	neural tube closure
GO:0035307	positive regulation of protein amino acid dephosphorylation
GO:0032321	positive regulation of Rho GTPase activity
GO:0032956	regulation of actin cytoskeleton organization
GO:0008360	regulation of cell shape
GO:0051056	regulation of small GTPase mediated signal transduction
GO:0007264	small GTPase mediated signal transduction

Cellular Component

GO:0005901	caveola
GO:0005737	cytoplasm
GO:0005829	cytosol
GO:0005925	focal adhesion
GO:0005634	nucleus

Molecular Function

GO:0005515	protein binding
GO:0030675	Rac GTPase activator activity
GO:0005100	Rho GTPase activator activity
GO:0042169	SH2 domain binding

deleted in liver cancer 1

Synonym

Expression Pattern

Choropleth map on BodyParts3D

Classification in 40 Organs

Gene Information

IDs

Orthologous Gene

Chromosomal Region

Gene Family (Interpro ID)

Link to Pubmed (Pubmed ID)

Gene Ontology (GO ID)

Biological Process

Cellular Component

Molecular Function