ATPase, aminophospholipid transporter (APLT), class I, type 8A, member 1

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Synonym

Probable phospholipid-transporting ATPase IA, MGC130043, Chromaffin granule ATPase II, ATPase class I type 8A member 1, ATPIA, ATPP2, MGC26327, ATP8A1, ATPASEII, MGC130042

Expression Pattern

Choropleth map on BodyParts3D

Choropleth maps on 3D human body images were generated by the relative gene expression values measured by GeneChip.

Classification in 40 Organs

brain blood connective
EST cerebrum:115 cerebellum:50.40 brain stem:- corpus callosum/glia:175 pineal gland:148.30 peripheral nerve:122.70 spine:449.20 retina:- eye:88.20 artery/aorta:89.90 vein:- lymphnode:222.40 peripheral blood:18.20 spleen:56.70 thymus:90.20 bone marrow:98.40 adipose:40.30 bone:12.80 skin:19.20
GeneChip cerebrum:8.81 cerebellum:7.31 brain stem:8.45 corpus callosum/glia:9.52 pineal gland:- peripheral nerve:8.25 spine:8.67 retina:- eye:- artery/aorta:5.74 vein:5.16 lymphnode:7.06 peripheral blood:- spleen:7.02 thymus:7.42 bone marrow:7.14 adipose:5.70 bone:- skin:4.81
CAGE cerebrum:5.01 cerebellum:- brain stem:5.03 corpus callosum/glia:5.50 pineal gland:4.71 peripheral nerve:- spine:5.10 retina:- eye:- artery/aorta:2.92 vein:4.06 lymphnode:3.99 peripheral blood:- spleen:3.70 thymus:4.27 bone marrow:- adipose:3.15 bone:- skin:-
RNA-seq cerebrum:4.12 cerebellum:- brain stem:- corpus callosum/glia:- pineal gland:- peripheral nerve:- spine:- retina:- eye:- artery/aorta:- vein:- lymphnode:0.00 peripheral blood:- spleen:- thymus:- bone marrow:- adipose:0.50 bone:- skin:-
reproductive muscular alimentary liver lung urinary endo/exo-crine
EST uterus:9.10 placenta:10.90 prostate:78.90 ovary:- testis:8.70 heart:25.50 muscle:60.30 esophagus:342.80 stomach:21.20 intestine:32.40 colon:42.40     liver/hepato:21.10        lung:14.70    bladder:- kidney:41.60 pituitary:116 thyroid/parathyroid:163.70 adrenal gland:50.80 pancreas:71.10 breast:27.90 salivary:-
GeneChip uterus:4.81 placenta:4.07 prostate:7.74 ovary:5.75 testis:4.33 heart:6.04 muscle:8.18 esophagus:4.85 stomach:6.27 intestine:6.08 colon:5.73 liver/hepato:4.52 lung:6.90 bladder:- kidney:5.28 pituitary:6.52 thyroid/parathyroid:8.67 adrenal gland:6.73 pancreas:5.13 breast:5.04 salivary:5.67
CAGE uterus:2.88 placenta:1.80 prostate:3.43 ovary:3.44 testis:2.37 heart:3.29 muscle:3.84 esophagus:2.84 stomach:- intestine:3.80 colon:3.91     liver/hepato:1.21    lung:4.49 bladder:2.87 kidney:2.49 pituitary:3.82 thyroid/parathyroid:5.22 adrenal gland:- pancreas:4.01 breast:3.16 salivary:3.17
RNA-seq uterus:- placenta:- prostate:0.67 ovary:1.30 testis:0.00 heart:1.98 muscle:2.93 esophagus:- stomach:- intestine:- colon:0.49     liver/hepato:0.00        lung:0.00    bladder:- kidney:0.64 pituitary:- thyroid/parathyroid:1.67 adrenal gland:0.00 pancreas:- breast:0.03 salivary:-

Gene Information

IDs

Refseq ID NM_006095
Gene ID 10396
Unigene ID Hs.435052
Probe set ID 213106_at  [HG-U133_Plus_2]
Ensembl ID ENSG00000124406
GTEx ID ENSG00000124406

Orthologous Gene

Mouse[8]  NM_001038999, NM_009727
Rat[8]  NM_001038999, NM_009727

Chromosomal Region

4p13  [42,410,390  -  42,659,122]

Gene Family (Interpro ID)

IPR001757  ATPase, P-type, K/Mg/Cd/Cu/Zn/Na/Ca/Na/H-transporter
IPR006539  ATPase, P-type, phospholipid-translocating, flippase

Link to Pubmed  (Pubmed ID)

8619474
9110174
9548971
10198212
11015572
12477932
15071553
15342556
15919184
17229723
18519826
19946888
20379614
21890473
21914794
22610502
23269685

Gene Ontology  (GO ID)

Biological Process

GO:0015917  aminophospholipid transport
GO:0034220  ion transmembrane transport
GO:0045332  phospholipid translocation
GO:0055085  transmembrane transport

Cellular Component

GO:0042584  chromaffin granule membrane
GO:0005783  endoplasmic reticulum
GO:0016021  integral to membrane
GO:0005886  plasma membrane

Molecular Function

GO:0015247  aminophospholipid transporter activity
GO:0005524  ATP binding
GO:0019829  cation-transporting ATPase activity
GO:0000287  magnesium ion binding
GO:0004012  phospholipid-translocating ATPase activity
GO:0005515  protein binding